114 research outputs found

    Characterization of spatio-temporal epidural event-related potentials for mouse models of psychiatric disorders.

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    Distinctive features in sensory event-related potentials (ERPs) are endophenotypic biomarkers of psychiatric disorders, widely studied using electroencephalographic (EEG) methods in humans and model animals. Despite the popularity and unique significance of the mouse as a model species in basic research, existing EEG methods applicable to mice are far less powerful than those available for humans and large animals. We developed a new method for multi-channel epidural ERP characterization in behaving mice with high precision, reliability and convenience and report an application to time-domain ERP feature characterization of the Sp4 hypomorphic mouse model for schizophrenia. Compared to previous methods, our spatio-temporal ERP measurement robustly improved the resolving power of key signatures characteristic of the disease model. The high performance and low cost of this technique makes it suitable for high-throughput behavioral and pharmacological studies

    Scaled Momentum Spectra in Deep Inelastic Scattering at HERA

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    Charged particle production has been studied in neutral current deep inelastic ep scattering with the ZEUS detector at HERA using an integrated luminosity of 0.44 fb?1. Distributions of scaled momenta in the Breit frame are presented for particles in the current fragmentation region. The evolution of these spectra with the photon virtuality, Q2, is described in the kinematic region 10 \u3c Q2\u3c 41000Ge V2. Next-to-leading-order and modified leading-log-approximation QCD calculations as well as predictions from Monte Carlo models are compared to the data. The results are also compared to e+e? annihilation data. The dependences of the pseudorapidity distribution of the particles on Q2 and on the energy in the p system, W, are presented and interpreted in the context of the hypothesis of limiting fragmentation

    Measurement of the t Dependence in Exclusive Photoproduction of Υ{hooked} (1S) Mesons at HERA

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    The exclusive photoproduction reaction γp→Υ{hooked} (1S)p has been studied with the ZEUS detector in ep collisions at HERA using an integrated luminosity of 468 pb -1. The measurement covers the kinematic range 6

    Search for First-generation Leptoquarks at HERA

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    A search for first-generation leptoquarks was performed in electron-proton and positron-proton collisions recorded with the ZEUS detector at HERA in 2003-2007 using an integrated luminosity of 366pb-1. Final states with an electron and jets or with missing transverse momentum and jets were analyzed, searching for resonances or other deviations from the standard model predictions. No evidence for any leptoquark signal was found. The data were combined with data previously taken at HERA, resulting in a total integrated luminosity of 498pb-1. Limits on the Yukawa coupling, λ, of leptoquarks were set as a function of the leptoquark mass for different leptoquark types within the Buchmüller-Rückl-Wyler model. Leptoquarks with a coupling λ=0.3 are excluded for masses up to 699 GeV. © 2012 American Physical Society

    Measurement of Inelastic J/ψ and ψ′ Photoproduction at HERA

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    The cross sections for inelastic photoproduction of J/ψ and ψ′ mesons have been measured in ep collisions with the ZEUS detector at HERA, using an integrated luminosity of 468 pb-1 collected in the period 1996-2007. The ψ′ to J/ψ cross section ratio was measured in the range 0.55 \u3c z \u3c 0.9 and 60 \u3c W \u3c 190 GeV as a function of W, z and pT. Here W denotes the photon-proton centre-of-mass energy, z is the fraction of the incident photon energy carried by the meson and p T is the transverse momentum of the meson with respect to the beam axis. The J/ψ cross sections were measured for 0.1 \u3c z \u3c 0.9, 60 \u3c W \u3c 240 GeV and pT \u3e 1 GeV. Theoretical predictions within the non-relativistic QCD framework including NLO colour-singlet and colour-octet contributions were compared to the data, as were predictions based on the k T-factorisation approach. © 2013 SISSA

    Search for Single-top Production in ep Collisions at HERA

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    A search for single-top production, ep→etX, has been performed with the ZEUS detector at HERA using data corresponding to an integrated luminosity of 0.37 fb -1. No evidence for top production was found, consistent with the expectation from the Standard Model. Limits were computed for single-top production via flavour changing neutral current transitions involving a neutral electroweak vector boson, γ or Z. The result was combined with a previous ZEUS result yielding a total luminosity of 0.50 fb -1. A 95% credibility level upper limit of 0.13 pb was obtained for the cross section at the centre-of-mass energy of √s=315 GeV. © 2012 Elsevier B.V

    Measurement of Beauty Production in Deep Inelastic Scattering at HERA Using Decays into Electrons

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    © The Author(s) 2011. The production of beauty quarks in ep interactions has been studied with the ZEUS detector at HERA for exchanged four-momentum squared Q2 \u3e 10 GeV2, using an integrated luminosity of 363 pb-1. The beauty events were identified using electrons from semileptonic b decays with a transverse momentum 0.9 \u3c peT \u3c 8 GeV and pseudorapidity |ηe| \u3c 1.5. Cross sections for beauty production were measured and compared with next-to-leadingorder QCD calculations. The beauty contribution to the proton structure function F2 was extracted from the doubledifferential cross section as a function of Bjorken-x and Q2

    Angular Correlations in Three-jet Events in ep Collisions at HERA

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    Three-jet production in deep inelastic ep scattering and photoproduction was investigated with the ZEUS detector at HERA using an integrated luminosity of up to 127pb-1. Measurements of differential cross sections are presented as functions of angular correlations between the three jets in the final state and the proton-beam direction. These correlations provide a stringent test of perturbative QCD and show sensitivity to the contributions from different color configurations. Fixed-order perturbative calculations assuming the values of the color factors CF, CA, and TF as derived from a variety of gauge groups were compared to the measurements to study the underlying gauge group symmetry. The measured angular correlations in the deep inelastic ep scattering and photoproduction regimes are consistent with the admixture of color configurations as predicted by SU(3) and disfavour other symmetry groups, such as SU(N) in the limit of large N. © 2012 American Physical Society

    Scaled Momentum Distributions for K \u3csub\u3eS\u3c/sub\u3e\u3csup\u3e0\u3c/sup\u3e and ∧/∧ in DIS at HERA

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    Scaled momentum distributions for the strange hadrons K S0 and ∧/∧were measured in deep inelastic ep scattering with the ZEUS detector at HERA using an integrated luminosity of 330 pb -1. The evolution of these distributions with the photon virtuality, Q 2, was studied in the kinematic region 10 \u3c Q 2 \u3c 40000 GeV 2 and 0.001 \u3c x \u3c 0.75, where x is the Bjorken scaling variable. Clear scaling violations are observed. Predictions based on different approaches to fragmentation were compared to the measurements. Leading-logarithm parton-shower Monte Carlo calculations interfaced to the Lund string fragmentation model describe the data reasonably well in the whole range measured. Nextto-leading-order QCD calculations based on fragmentation functions, FFs, extracted from e +e - data alone, fail to describe the measurements. The calculations based on FFs extracted from a global analysis including e +e -, ep and pp data give an improved description. The measurements presented in this paper have the potential to further constrain the FFs of quarks, anti-quarks and gluons yielding K S0 and ∧/∧ strange hadrons. © SISSA 2012
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