1,800 research outputs found
Recommended Selective Maintenance and Rehabilitation Treatment Approach for Air Force Primary Rigid Runway Pavement Systems
The Air Force is facing the challenge to preserve the current inventory of 154 million square yards of paved airfield assets while at the same time reducing the budget by $36.2 billion between fiscal years 2015-2019. This research sought to determine a selective maintenance and rehabilitation treatment approach that allocates resources efficiently to preserve the degrading pavement assets in the financially constrained environment. Air Force pavement inspection reports from the past five years provided 4289 observed pavement distress data points for this research. The data was inputted into the pavement management software, PAVER, to calculate the Pavement Condition Index (PCI) deduct values for every pavement distress combinations. A pavement distress prioritization list was created from the 111 PCI deduct value calculations to rank the impact that different distresses have on the condition of pavement systems. The analysis led to the recommended selective maintenance and rehabilitation treatment approach of treating all medium and high severity joint seal damage with joint seal repair, repairing all pavement slabs with slab replacement that had a PCI less than 70 and with a PCI deduct greater than 10, and using all remaining resources on the Air Force recommended treatments. The recommended approach minimizes the potential of Foreign Object Damage, uses corrective measures in the form of slab replacement to repair the worst conditioned and highest priority slabs, and reduces further pavement degradation with the Air Force recommended treatments
Teaching and Learning SoTL: Preparing future faculty in a pedagogy course
The Scholarship of Teaching and Learning (SoTL) offers a way of equipping graduate students for monitoring, assessing, and reflecting on their teaching and their students’ learning in higher education. After reviewing recent literature about the ways graduate students prepare for teaching, this essay presents an example of one way SoTL can inform teaching and teacher education as part of a graduate seminar. When a SoTL approach was integrated into a course about teaching in higher education, the course itself became a faculty-graduate student collaborative project. This essay demonstrates the potent circularity of the reflective teaching practice that drives the course and inspires similar practice in its students, which in turn informs subsequent iterations of the course
Fibrosis in diabetes complications: Pathogenic mechanisms and circulating and urinary markers
Diabetes mellitus is characterized by a lack of insulin causing elevated blood glucose, often with associated insulin resistance. Over time, especially in genetically susceptible individuals, such chronic hyperglycemia can cause tissue injury. One pathological response to tissue injury is the development of fibrosis, which involves predominant extracellular matrix (ECM) accumulation. The main factors that regulate ECM in diabetes are thought to be pro-sclerotic cytokines and protease/anti-protease systems. This review will examine the key markers and regulators of tissue fibrosis in diabetes and whether their levels in biological fluids may have clinical utility
Variation of the Diameter of the Sun as Measured by the Solar Disk Sextant (SDS)
The balloon-borne Solar Disk Sextant (SDS) experiment has measured the
angular size of the Sun on seven occasions spanning the years 1992 to 2011. The
solar half-diameter -- observed in a 100-nm wide passband centred at 615 nm --
is found to vary over that period by up to 200 mas, while the typical estimated
uncertainty of each measure is 20 mas. The diameter variation is not in phase
with the solar activity cycle; thus, the measured diameter variation cannot be
explained as an observational artefact of surface activity. Other possible
instrument-related explanations for the observed variation are considered but
found unlikely, leading us to conclude that the variation is real. The SDS is
described here in detail, as is the complete analysis procedure necessary to
calibrate the instrument and allow comparison of diameter measures across
decades.Comment: 41 pages; appendix and 2 figures added plus some changes in text
based on referee's comments; to appear in MNRA
Operation of EMEP ‘supersites’ in the United Kingdom. Annual report for 2008.
As part of its commitment to the UN-ECE Convention on Long-range Transboundary Air Pollution the United Kingdom operates two ‘supersites’ reporting data to the Co-operative Programme for Monitoring and Evaluation of the Long-range Transmission of Air Pollutants in Europe (EMEP).
This report provides the annual summary for 2008, the second full calendar year of operation of the first EMEP ‘supersite’ to be established in the United Kingdom. Detailed operational reports have been submitted to Defra every 3 months, with unratified data. This annual report contains a summary of the ratified data for 2008.
The EMEP ‘supersite’ is located in central southern Scotland at Auchencorth (3.2oW, 55.8oN), a remote rural moorland site ~20 km south-west of Edinburgh. Monitoring operations started formally on 1 June 2006.
In addition to measurements made specifically under this contract, the Centre for Ecology & Hydrology also acts as local site operator for measurements made under other UK monitoring networks: the Automated Urban and Rural Network (AURN), the UK Eutrophication and Acidification Network (UKEAP), the UK Hydrocarbons Network, and the UK Heavy Metals Rural Network. Some measurements were also made under the auspices of the ‘Air Pollution Deposition Processes’ contract. All these associated networks are funded by Defra.
This report summarises the measurements made between January and December 2008, and presents summary statistics on average concentrations.
The site is dominated by winds from the south-west, but wind direction data highlight potential sources of airborne pollutants (power stations, conurbations).
The average diurnal patterns of gases and particles are consistent with those expected for a remote rural site.
The frequency distributions are presented for data where there was good data capture throughout the whole period. Some components (e.g. black carbon) show log-normal frequency distributions, while other components (e.g. ozone) have more nearly normal frequency distributions.
A case study is presented for a period in June 2008, showing the influence of regional air pollutants at this remote rural site.
All the data reported under the contract are shown graphically in the Appendix
Interference with the germination and growth of Ulvazoospores by quorum-sensing molecules from Ulva-associated epiphytic bacteria
Ulva zoospores preferentially settle on N-acylhomoserine
lactone (AHL) producing marine bacterial
biofilms. To investigate whether AHL signal molecules
also affect the success and rate of zoospore germination
in addition to zoospore attraction, the epiphytic
bacteria associated with mature Ulva linza were characterized
and bacterial isolates representative of this
community tested for the ability to produce AHLs. Two
of these AHL-producing isolates, Sulfitobacter spp.
376 and Shewanella spp. 79, were transformed with
plasmids expressing the Bacillus spp. AHL lactonase
gene aiiA to generate AHL-deficient variants. The germination
and growth of U. linza zoospores was studied
in the presence of these AHL-deficient strains and
their AHL-producing counterparts. This revealed that
the AHLs produced by Sulfitobacter spp. and
Shewanella spp. or the bacterial products they regulate
have a negative impact on both zoospore germination
and the early growth of the Ulva germling.
Further experiments with Escherichia coli biofilms
expressing recombinant AHL synthases and synthetic
AHLs provide data to demonstrate that zoospores
germinated and grown in the absence of AHLs were
significantly longer than those germinated in the presence
of AHLs. These results reveal an additional role
for AHLs per se in the interactive relationships
between marine bacteria and Ulva zoospores
The economic benefits of increased levels of nursing care in the hospital setting
Aim: To assess the economic impact of increased nursing hours of care on health outcomes in adult teaching hospitals in Perth, Western Australia. Background: Advancing technology and increased availability of treatment interventions are increasing demand for health care while the downturn in world economies has increased demand for greater efficiency. Nurse managers must balance nurse staffing to optimize care and provide efficiencies. Design: This longitudinal study involved the retrospective analysis of a cohort of multi-day stay patients admitted to adult teaching hospitals. Methods: Hospital morbidity and staffing data from September 2000 until June 2004, obtained in 2010 from a previous study, were used to analyse nursing-sensitive outcomes pre- and post-implementation of the Nurse Hours per Patient Day staffing method, which remains in place today. The cost of the intervention comprised increased nursing hours following implementation of the staffing method. Results: The number of nursing-sensitive outcomes was 1357 less than expected post-implementation and included 155 fewer \u27failure to rescue\u27 events. The 1202 other nursing-sensitive outcomes prevented were \u27surgical wound infection\u27, \u27pulmonary failure\u27, \u27ulcer, gastritis\u27, \u27upper gastrointestinal bleed\u27, and \u27cardiac arrest\u27. One outcome, pneumonia, showed an increase of 493. Analysis of life years gained was based on the failure to rescue events prevented and the total life years gained was 1088. The cost per life year gained was AUD$8907. Conclusion: The implementation of the Nurse Hours per Patient Day staffing method was cost-effective when compared with thresholds of interventions commonly accepted in Australia
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