231 research outputs found

    Present-day Risk of Occasional Extreme Hydrological and Hydrogeological Events

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    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchive

    Experience of organization of the system of psychological and pedagogical professional development of teachers of higher educational institutions

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    The relevance of the researched problem is caused by the changed social and economic conditions in Russia that led to search of the paradigms of education adequate to new social and economic development of the country. The presented article is directed to drawing attention of the pedagogical public to modern forms of organization of the system of advanced training of employees of higher education. The leading approach to the research of this problem is the analysis of experience of practical activities of Russian State Vocational Pedagogical University; this approach enables to fill educational practice with new constructs and meanings. As a result of the research, the model of implementation of the system of advanced training of employees of higher education is proposed. The material of the publication can be useful while developing and projecting of programs for professional psychological and pedagogical qualification development of teachers in the system of higher education, including its network use in the space of vocational pedagogical education. © 2016 Akimova et al

    On the impact of nanometric γ’ precipitates on the tensile deformation of superelastic Co49Ni21Ga30

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    Results are presented reporting on the martensite domain variant selection and stress-induced martensite morphology in [001]-oriented superelastic Co49Ni21Ga30 shape memory alloy (SMA) single crystals under tensile load. In situ neutron diffraction, as well as in situ optical- and confocal laser scanning microscopy were conducted focusing on three differently treated samples, i.e. in the as-grown, solution-annealed and aged condition. An aging treatment performed at 350 °C promotes the precipitation of nanoprecipitates. These second phase precipitates contribute to an increase of the number of habit plane interfaces, while reducing lamellar martensite plate thickness compared to the as-grown and solution-annealed (precipitate free) samples. During tensile loading, all samples show a stress-induced formation of martensite, characterized by one single domain variant (“detwinned”) and one set of parallel habit planes in a shear band. The results clearly show that γ’ nanoprecipitates do not necessarily promote multi-variant interaction during tensile loading. Thus, reduced recoverability in Co-Ni-Ga SMAs upon aging cannot be solely attributed to this kind of interaction as has been proposed in literature so far

    Hemostasis disturbance correction using reamberin in patients with abdominal sepsis

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    The aim of our investigation was to estimate the possibility of reamberin usage for correction of hemostasis disturbances in patients with abdominal sepsis. We have analysed results of treatment in 78 patients with abdominal sepsis: 65 patients with standard complex therapy, 13 - standard therapy with addition of reamberin. We could observe differently directed disturbances of thrombocytic and coagulation parts of hemostasis. Reamberin promoted the restoration and stabilization of the equilibrium between the different parts of hemostasis, leading to the favorable outcomes in patients with sepsis.Цель исследования - оценить эффективность использования реамберина для коррекции нарушений гемостаза при абдоминальном сепсисе. Обследовано и пролечено 78 пациентов с абдоминальным сепсисом, из них 65 пациентам проведен стандартный комплекс интенсивной терапии, а у 13 пациентов в комплекс интенсивной терапии был включен реамберин. Абдоминальный сепсис вызывает разнонаправленные нарушения сосудисто-тромбоцитарного и коагуляционного звеньев гемостаза. Реамберин способствует восстановлению и стабилизации равновесия между всеми звеньями системы гемостаза, что оказывает благоприятное влияние на исход септического процесса

    Changing climate both increases and decreases European river floods

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    Climate change has led to concerns about increasing river floods resulting from the greater water-holding capacity of a warmer atmosphere1. These concerns are reinforced by evidence of increasing economic losses associated with flooding in many parts of the world, including Europe2. Any changes in river floods would have lasting implications for the design of flood protection measures and flood risk zoning. However, existing studies have been unable to identify a consistent continental-scale climatic-change signal in flood discharge observations in Europe3, because of the limited spatial coverage and number of hydrometric stations. Here we demonstrate clear regional patterns of both increases and decreases in observed river flood discharges in the past five decades in Europe, which are manifestations of a changing climate. Our results\u2014arising from the most complete database of European flooding so far\u2014suggest that: increasing autumn and winter rainfall has resulted in increasing floods in northwestern Europe; decreasing precipitation and increasing evaporation have led to decreasing floods in medium and large catchments in southern Europe; and decreasing snow cover and snowmelt, resulting from warmer temperatures, have led to decreasing floods in eastern Europe. Regional flood discharge trends in Europe range from an increase of about 11 per cent per decade to a decrease of 23 per cent. Notwithstanding the spatial and temporal heterogeneity of the observational record, the flood changes identified here are broadly consistent with climate model projections for the next century4,5, suggesting that climate-driven changes are already happening and supporting calls for the consideration of climate change in flood risk management

    11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

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    Expression of CCN family of genes in human skin in vivo and alterations by solar-simulated ultraviolet irradiation

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    The CCN family of proteins is involved in diverse biological functions such as cell growth, adhesion, migration, angiogenesis, and regulation of extracellular matrix. We have investigated expression of CCN family genes and alternations induced by solar-simulated ultraviolet irradiation in human skin in vivo. Transcripts of all six CCN genes were expressed in human skin in vivo. CCN5 was most abundantly expressed followed by CCN2>CCN3>CCN1>CCN4>CCN6. Solar-simulated ultraviolet irradiation increased mRNA expression of CCN1 and CCN2. In contrast, mRNA levels of CCN3, CCN4, CCN5, and CCN6, were reduced. Knowledge gained from this study provides the foundation to explore the functional roles of CCN gene products in cutaneous biology and responses to solar ultraviolet irradiation
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