7,963 research outputs found
Inhibition of Shh signalling in the chick wing gives insights into digit patterning and evolution.
In an influential model of pattern formation, a gradient of Sonic hedgehog (Shh) signalling in the chick wing bud specifies cells with three antero-posterior positional values, which give rise to three morphologically different digits by a self-organizing mechanism with Turing-like properties. However, as four of the five digits of the mouse limb are morphologically similar in terms of phalangeal pattern, it has been suggested that self-organization alone could be sufficient. Here, we show that inhibition of Shh signalling at a specific stage of chick wing development results in a pattern of four digits, three of which can have the same number of phalanges. These patterning changes are dependent on a posterior extension of the apical ectodermal ridge, and this also allows the additional digit to arise from the Shh-producing cells of the polarizing region - an ability lost in ancestral theropod dinosaurs. Our analyses reveal that, if the specification of antero-posterior positional values is curtailed, self-organization can then produce several digits with the same number of phalanges. We present a model that may give important insights into how the number of digits and phalanges has diverged during the evolution of avian and mammalian limbs
Consumer choice for quality and sustainability in seafood products: empirical findings from United Kingdom
A facial expression for anxiety.
Anxiety and fear are often confounded in discussions of human emotions. However, studies of rodent defensive reactions under naturalistic conditions suggest anxiety is functionally distinct from fear. Unambiguous threats, such as predators, elicit flight from rodents (if an escape-route is available), whereas ambiguous threats (e.g., the odor of a predator) elicit risk assessment behavior, which is associated with anxiety as it is preferentially modulated by anti-anxiety drugs. However, without human evidence, it would be premature to assume that rodent-based psychological models are valid for humans. We tested the human validity of the risk assessment explanation for anxiety by presenting 8 volunteers with emotive scenarios and asking them to pose facial expressions. Photographs and videos of these expressions were shown to 40 participants who matched them to the scenarios and labeled each expression. Scenarios describing ambiguous threats were preferentially matched to the facial expression posed in response to the same scenario type. This expression consisted of two plausible environmental-scanning behaviors (eye darts and head swivels) and was labeled as anxiety, not fear. The facial expression elicited by unambiguous threat scenarios was labeled as fear. The emotion labels generated were then presented to another 18 participants who matched them back to photographs of the facial expressions. This back-matching of labels to faces also linked anxiety to the environmental-scanning face rather than fear face. Results therefore suggest that anxiety produces a distinct facial expression and that it has adaptive value in situations that are ambiguously threatening, supporting a functional, risk-assessing explanation for human anxiet
The impact of the 1783-1784 AD Laki eruption on global aerosol formation processes and cloud condensation nuclei
The 1783–1784 AD Laki flood lava eruption commenced on 8 June 1783 and released 122 Tg of sulphur dioxide gas over the course of 8 months into the upper troposphere and lower stratosphere above Iceland. Previous studies have examined the impact of the Laki eruption on sulphate aerosol and climate using general circulation models. Here, we study the impact on aerosol microphysical processes, including the nucleation of new particles and their growth to cloud condensation nuclei (CCN) using a comprehensive Global Model of Aerosol Processes (GLOMAP). Total particle concentrations in the free troposphere increase by a factor ~16 over large parts of the Northern Hemisphere in the 3 months following the onset of the eruption. Particle concentrations in the boundary layer increase by a factor 2 to 5 in regions as far away as North America, the Middle East and Asia due to long-range transport of nucleated particles. CCN concentrations (at 0.22% supersaturation) increase by a factor 65 in the upper troposphere with maximum changes in 3-month zonal mean concentrations of ~1400 cm<sup>−3</sup> at high northern latitudes. 3-month zonal mean CCN concentrations in the boundary layer at the latitude of the eruption increase by up to a factor 26, and averaged over the Northern Hemisphere, the eruption caused a factor 4 increase in CCN concentrations at low-level cloud altitude. The simulations show that the Laki eruption would have completely dominated as a source of CCN in the pre-industrial atmosphere. The model also suggests an impact of the eruption in the Southern Hemisphere, where CCN concentrations are increased by up to a factor 1.4 at 20&deg; S. Our model simulations suggest that the impact of an equivalent wintertime eruption on upper tropospheric CCN concentrations is only about one-third of that of a summertime eruption. The simulations show that the microphysical processes leading to the growth of particles to CCN sizes are fundamentally different after an eruption when compared to the unperturbed atmosphere, underlining the importance of using a fully coupled microphysics model when studying long-lasting, high-latitude eruptions
Choice experiments for quality and sustainability in seafood products: empirical findings from United Kingdom
Observations of ozone production in a dissipating tropical convective cell during TC4
From 13 July–9 August 2007, 25 ozonesondes were launched from Las Tablas, Panama as part of the Tropical Composition, Cloud, and Climate Coupling (TC4) mission. On 5 August, a strong convective cell formed in the Gulf of Panama. World Wide Lightning Location Network (WWLLN) data indicated 563 flashes (09:00–17:00 UTC) in the Gulf. NO2 data from the Ozone Monitoring Instrument (OMI) show enhancements, suggesting lightning production of NOx. At 15:05 UTC, an ozonesonde ascended into the southern edge of the now dissipating convective cell as it moved west across the Azuero Peninsula. The balloon oscillated from 2.5–5.1 km five times (15:12–17:00 UTC), providing a unique examination of ozone (O3) photochemistry on the edge of a convective cell. Ozone increased at a rate of 1.6–4.6 ppbv/hr between the first and last ascent, resulting cell wide in an increase of (2.1–2.5)×106 moles of O3. This estimate agrees to within a factor of two of our estimates of photochemical lightning O3 production from the WWLLN flashes, from the radar-inferred lightning flash data, and from the OMI NO2 data (1.2, 1.0, and 1.7×106 moles, respectively), though all estimates have large uncertainties. Examination of DC-8 in situ and lidar O3 data gathered around the Gulf that day suggests 70–97% of the O3 change occurred in 2.5–5.1 km layer. A photochemical box model initialized with nearby TC4 aircraft trace gas data suggests these O3 production rates are possible with our present understanding of photochemistry
Fe I Oscillator Strengths for the Gaia-ESO Survey
The Gaia-ESO Public Spectroscopic Survey (GES) is conducting a large-scale
study of multi-element chemical abundances of some 100 000 stars in the Milky
Way with the ultimate aim of quantifying the formation history and evolution of
young, mature and ancient Galactic populations. However, in preparing for the
analysis of GES spectra, it has been noted that atomic oscillator strengths of
important Fe I lines required to correctly model stellar line intensities are
missing from the atomic database. Here, we present new experimental oscillator
strengths derived from branching fractions and level lifetimes, for 142
transitions of Fe I between 3526 {\AA} and 10864 {\AA}, of which at least 38
are urgently needed by GES. We also assess the impact of these new data on
solar spectral synthesis and demonstrate that for 36 lines that appear
unblended in the Sun, Fe abundance measurements yield a small line-by-line
scatter (0.08 dex) with a mean abundance of 7.44 dex in good agreement with
recent publications.Comment: Accepted for publication in Mon. Not. R. Astron. So
Divergence in Dialogue
Copyright: 2014 Healey et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This work was supported by the Economic and Social Research Council (ESRC; http://www.esrc.ac.uk/) through the DynDial project (Dynamics of Conversational Dialogue, RES-062-23-0962) and the Engineering and Physical Sciences Research Council (EPSRC; http://www.epsrc.ac.uk/) through the RISER
project (Robust Incremental Semantic Resources for Dialogue, EP/J010383/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript
Atomic and Molecular Data for Optical Stellar Spectroscopy
High-precision spectroscopy of large stellar samples plays a crucial role for
several topical issues in astrophysics. Examples include studying the chemical
structure and evolution of the Milky Way galaxy, tracing the origin of chemical
elements, and characterizing planetary host stars. Data are accumulating from
instruments that obtain high-quality spectra of stars in the ultraviolet,
optical and infrared wavelength regions on a routine basis. These instruments
are located at ground-based 2- to 10-m class telescopes around the world, in
addition to the spectrographs with unique capabilities available at the Hubble
Space Telescope. The interpretation of these spectra requires high-quality
transition data for numerous species, in particular neutral and singly ionized
atoms, and di- or triatomic molecules. We rely heavily on the continuous
efforts of laboratory astrophysics groups that produce and improve the relevant
experimental and theoretical atomic and molecular data. The compilation of the
best available data is facilitated by databases and electronic infrastructures
such as the NIST Atomic Spectra Database, the VALD database, or the Virtual
Atomic and Molecular Data Centre (VAMDC). We illustrate the current status of
atomic data for optical stellar spectra with the example of the Gaia-ESO Public
Spectroscopic Survey. Data sources for 35 chemical elements were reviewed in an
effort to construct a line list for a homogeneous abundance analysis of up to
100000 stars.Comment: Published 30 April 2015 in Physica Script
Energy Flow in Acoustic Black Holes
We present the results of an analysis of superradiant energy flow due to
scalar fields incident on an acoustic black hole. In addition to providing
independent confirmation of the recent results in [5], we determine in detail
the profile of energy flow everywhere outside the horizon. We confirm
explicitly that in a suitable frame the energy flow is inward at the horizon
and outward at infinity, as expected on physical grounds.Comment: 8 pages, 9 figures, Comments added to discussion of energy flow and
introductory section abbreviate
- …