1,769 research outputs found
Simulation of the White Dwarf -- White Dwarf galactic background in the LISA data
LISA (Laser Interferometer Space Antenna) is a proposed space mission, which
will use coherent laser beams exchanged between three remote spacecraft to
detect and study low-frequency cosmic gravitational radiation. In the low-part
of its frequency band, the LISA strain sensitivity will be dominated by the
incoherent superposition of hundreds of millions of gravitational wave signals
radiated by inspiraling white-dwarf binaries present in our own galaxy. In
order to estimate the magnitude of the LISA response to this background, we
have simulated a synthesized population that recently appeared in the
literature. We find the amplitude of the galactic white-dwarf binary background
in the LISA data to be modulated in time, reaching a minimum equal to about
twice that of the LISA noise for a period of about two months around the time
when the Sun-LISA direction is roughly oriented towards the Autumn equinox.
Since the galactic white-dwarfs background will be observed by LISA not as a
stationary but rather as a cyclostationary random process with a period of one
year, we summarize the theory of cyclostationary random processes and present
the corresponding generalized spectral method needed to characterize such
process. We find that, by measuring the generalized spectral components of the
white-dwarf background, LISA will be able to infer properties of the
distribution of the white-dwarfs binary systems present in our Galaxy.Comment: 14 pages and 6 figures. Submitted to Classical and Quantum Gravity
(Proceedings of GWDAW9
Observation of a Free-Shercliff-Layer Instability in Cylindrical Geometry
We report on observations of a free-Shercliff-layer instability in a
Taylor-Couette experiment using a liquid metal over a wide range of Reynolds
numbers, . The free Shercliff layer is formed by imposing a
sufficiently strong axial magnetic field across a pair of differentially
rotating axial endcap rings. This layer is destabilized by a hydrodynamic
Kelvin-Helmholtz-type instability, characterized by velocity fluctuations in
the plane. The instability appears with an Elsasser number above
unity, and saturates with an azimuthal mode number which increases with the
Elsasser number. Measurements of the structure agree well with 2D global linear
mode analyses and 3D global nonlinear simulations. These observations have
implications for a range of rotating MHD systems in which similar shear layers
may be produced.Comment: 5 pages, 4 figure
Novel self-assembled morphologies from isotropic interactions
We present results from particle simulations with isotropic medium range
interactions in two dimensions. At low temperature novel types of aggregated
structures appear. We show that these structures can be explained by
spontaneous symmetry breaking in analytic solutions to an adaptation of the
spherical spin model. We predict the critical particle number where the
symmetry breaking occurs and show that the resulting phase diagram agrees well
with results from particle simulations.Comment: 4 pages, 4 figure
Spontal-N: A Corpus of Interactional Spoken Norwegian
Spontal-N is a corpus of spontaneous, interactional Norwegian. To our knowledge, it is the first corpus of Norwegian in which the majority of speakers have spent significant parts of their lives in Sweden, and in which the recorded speech displays varying degrees of interference from Swedish. The corpus consists of studio quality audio- and video-recordings of four 30-minute free conversations between acquaintances, and a manual orthographic transcription of the entire material. On basis of the orthographic transcriptions, we automatically annotated approximately 50 percent of the material on the phoneme level, by means of a forced alignment between the acoustic signal and pronunciations listed in a dictionary. Approximately seven percent of the automatic transcription was manually corrected. Taking the manual correction as a gold standard, we evaluated several sources of pronunciation variants for the automatic transcription. Spontal-N is intended as a general purpose speech resource that is also suitable for investigating phonetic detail
Turbulence and jet-driven zonal flows: Secondary circulation in rotating fluids due to asymmetric forcing
We report on experiments and modeling on a rotating confined liquid that is forced by circumferential jets coaxial with the rotation axis, wherein system-scale secondary flows are observed to emerge. The jets are evenly divided in number between inlets and outlets and have zero net mass transport. For low forcing strengths the sign of this flow depends on the sign of a sloped end cap, which simulates a planetary ÎČ plane. For increased forcing strengths the secondary flow direction is insensitive to the slope sign, and instead appears to be dominated by an asymmetry in the forcing mechanism, namely, the difference in radial divergence between the inlet and outlet jet profiles. This asymmetry yields a net radial velocity that is affected by the Coriolis force, inducing secondary zonal flow
Risk of adverse events in patients prescribed longâterm opioids: a cohort study in the UK Clinical Practice Research Datalink
Background
Longâterm opioid prescribing for musculoskeletal pain is controversial due to uncertainty regarding effectiveness and safety. This study examined the risks of a range of adverse events in a large cohort of patients prescribed longâterm opioids using the UK Clinical Practice Research Datalink.
Methods
Patients with musculoskeletal conditions starting a new longâterm opioid episode (defined as â„3 opioid prescriptions within 90 days) between 2002 and 2012 were included. Primary outcomes: major trauma and intentional overdose (any). Secondary outcomes: addiction (any), falls, accidental poisoning, attempted suicide/selfâharm, gastrointestinal pathology and bleeding, and iron deficiency anaemia. âControlâ outcomes (unrelated to opioid use): incident eczema and psoriasis.
Results
A total of 98,140 new longâterm opioids users (median age 61, 41% male) were followed for (median) 3.4 years. Major trauma risk increased from 285 per 10,000 personâyears without longâterm opioids to 369/10,000 for a longâterm opioid episode (<20 mg MED), 382/10,000 (20â50 mg MED), and 424/10,000 (â„50 mg MED). Adjusted hazard ratios were 1.09 (95% CI; 1.04, 1.14 for <20 mg MED vs. not being in an episode of longâterm prescribing), 1.24 (95% CI; 1.16, 1.32: 20â50 mg MED) and 1.34 (95% CI; 1.20, 1.50: â„50 mg MED). Significant doseâdependent increases in the risk of overdose (any type), addiction, falls, accidental poisoning, gastrointestinal pathology, and iron deficiency anaemia were also found.
Conclusions
Patients prescribed longâterm opioids are vulnerable to doseâdependent serious adverse events. Opioid prescribing should be reviewed before longâterm use becomes established, and periodically thereafter to ensure that patients are not being exposed to increased risk of harm, which is not balanced by therapeutic benefit.
Significance
Longâterm opioid use is associated with serious adverse events such as major trauma, addiction and overdose. The risk increases with higher opioid doses. Opioid prescribing should be reviewed before longâterm use becomes established, and periodically thereafter to assess ongoing effectiveness
Localized phase contrast imaging at the Wendelstein 7-X stellarator
In its basic form, phase contrast imaging (PCI) provides line-integrated measurements of electron density fluctuations in plasmas. As turbulent fluctuations in magnetically confined plasmas have wave vectors almost perpendicular to the background magnetic field, the signals scattered by fluctuations from different parts of the PCI line-of-sight (LoS) are spatially separated in focal planes of the plasma. This allows localized PCI measurements by placing a mask in such a plane, to only permit signals from specific parts of the LoS to reach the PCI detectors. The present paper describes modeling and design of localization masks for the PCI system at the Wendelstein 7-X (W7-X) stellarator as well as the first results obtained using the masks in the recent long-pulse W7-X experimental campaign. During this project, we have extended the theory describing the mask response within the Fraunhofer diffraction model. As a novel development, we show from first principles that the mask response is determined by the fraction of power of the scattered beam spots that passes the mask. These insights have been used to select the W7-X mask design, consisting of a circular cutout, allowing the unscattered beam spot to pass the mask, with wedges covering a fixed angular range outside the central cutout. In the recent W7-X experimental campaign, the masks have verified the location of the main turbulence features observed by the PCI system and provided new information about the location of short-wavelength magnetohydrodynamic modes
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