437 research outputs found
Effects of alloying on aging and hardening processes of steel with 20% nickel
Measurements of hardness, thermal emf, and electrical resistance were used to study the effects of Co, Mo, Ti and Al contents on aging and hardening processes in Fe 20%Ni steel. It is shown that the effects of these alloying elements differ substantially. Anomalies which arise in the temperature dependence of physical properties due to the presence of cobalt and molybdenum are reduced by the inclusion of titanium and aluminum (and vice versa)
ОТ ПОВЕДЕНЧЕСКОГО АНАЛИЗА К ПОСТ-БИХЕВИОРАЛИЗМУ: ИСТОРИЯ ПАРАДИГМЫ
Article is devoted to the review of formation and decline of behavioralism paradigm in political science. The author begins the analysis with critical consideration of the scientific concepts preceding emergence of modernist empiricism within which there is a behavioral analysis. Further the researcher traces formation behaviorism in the social disciplines: formation model in psychology, release of the theory out of limits of pure psychology and transferring ideas in sociology and political science. The author analyzes inquiries to the scientific theory by behavioralism. He opens the principles of behavioralism as paradigm in political science. The author presents the conceptual and contextual factors promoting recession of popularity behavioralism in political science and submits methodological restrictions approach. The author states the main claims of critics to this research approach and explains the reasons decline this paradigm. At the same time the methodological reflection of behavioralism which has followed recession of his popularity is reflected in work. The author opens the principles of the new methodological direction – post-behavioralism and the position of modern representatives of the behavioral analysis.Статья посвящена обзору становления и упадка бихевиоралистской парадигмы в политологии. Автор начинает анализ с критического рассмотрения научных концепций, предшествующих появлению модернистского эмпиризма, в рамках которого возникает поведенческий анализ. Далее исследователь прослеживает путь становления бихевиоризма в русле обществоведческих дисциплин: формирование модели в психологии, выход теории за пределы чистой психологии и перенесение ее идей сначала в социологию, а после и в политологию. Автор анализирует гносеологические запросы бихевиорализма к научной теории и раскрывает принципы бихевиорализма как политологической парадигмы. В работе представлены концептуальные и контекстуальные факторы, способствовавшие спаду популярности бихевиорализма в политической науке, рассматриваются его методологические ограничения. Автор излагает основные претензии критиков к данному исследовательскому подходу и объясняет причины упадка данной парадигмы. Вместе с тем, в работе отражена и методологическая рефлексия бихевиорализма, последовавшая за спадом его популярности, раскрыты принципы нового направления – пост-бихевиорализма, а также изложена позиция современных представителей поведенческого анализа по некотором методологическим вопросам.
Equilibrium states and invariant measures for random dynamical systems
Random dynamical systems with countably many maps which admit countable
Markov partitions on complete metric spaces such that the resulting Markov
systems are uniformly continuous and contractive are considered. A
non-degeneracy and a consistency conditions for such systems, which admit some
proper Markov partitions of connected spaces, are introduced, and further
sufficient conditions for them are provided. It is shown that every uniformly
continuous Markov system associated with a continuous random dynamical system
is consistent if it has a dominating Markov chain. A necessary and sufficient
condition for the existence of an invariant Borel probability measure for such
a non-degenerate system with a dominating Markov chain and a finite (16) is
given. The condition is also sufficient if the non-degeneracy is weakened with
the consistency condition. A further sufficient condition for the existence of
an invariant measure for such a consistent system which involves only the
properties of the dominating Markov chain is provided. In particular, it
implies that every such a consistent system with a finite Markov partition and
a finite (16) has an invariant Borel probability measure. A bijective map
between these measures and equilibrium states associated with such a system is
established in the non-degenerate case. Some properties of the map and the
measures are given.Comment: The article is published in DCDS-A, but without the 3rd paragraph on
page 4 (the complete removal of the paragraph became the condition for the
publication in the DCDS-A after the reviewer ran out of the citation
suggestions collected in the paragraph
The Temperature-Dependent Selectivity of Potential Interaction Partners for the Small Heat Shock Protein IbpA from Acholeplasma laidlawii
© 2016, Springer Science+Business Media New York.Small heat shock proteins (sHsps) of α-crystalline type play a key role in the cell survival under stress conditions by preventing irreversible denaturation and aggregation of proteins. In contrast to most Mollicutes (mycoplasmas) where no sHsps were found, recently, some sHsp homologs were identified in the Acholeplasmataceae family, including Acholeplasma laidlawii, the only representative of Mollicutes that is known to survive in a host-free environment. Using pull-down followed by LC-MS, we identified the potential target proteins co-eluting with IbpA from the A. laidlawii cell extracts after exposition to low- and high temperatures. 308 and 464 proteins were co-eluted with IbpA from the cold- and heat-treated extracts, respectively, while only 240 of them were co-eluted with sHsp independently of the temperature. Most of potential IbpA targets were identified as enzymes involved in biosynthetic cycles and energy metabolism. We show IbpA specificity for target proteins on the incubation temperature. Significant differences between protein pools co-eluting specifically with IbpA at either 4 or 46 °C could be observed in terms of their aliphatic index, charge, molecular weight, and isoelectric point. Interestingly, only the isoelectric point distribution significantly differed between the protein pool co-eluting with IbpA under cooling (4 °C) and the entire proteome. In contrast, significant discrepancies in the distributions of aliphatic index, charge, hydropathy, molecular weight, and isoelectric point could be observed between the pool of proteins co-eluting with IbpA under heating (46 °C) and the entire proteome, indicating that there is likely a complex selective mechanism for proteins interaction with IbpA under heat shock conditions
Fisher Information for Inverse Problems and Trace Class Operators
This paper provides a mathematical framework for Fisher information analysis
for inverse problems based on Gaussian noise on infinite-dimensional Hilbert
space. The covariance operator for the Gaussian noise is assumed to be trace
class, and the Jacobian of the forward operator Hilbert-Schmidt. We show that
the appropriate space for defining the Fisher information is given by the
Cameron-Martin space. This is mainly because the range space of the covariance
operator always is strictly smaller than the Hilbert space. For the Fisher
information to be well-defined, it is furthermore required that the range space
of the Jacobian is contained in the Cameron-Martin space. In order for this
condition to hold and for the Fisher information to be trace class, a
sufficient condition is formulated based on the singular values of the Jacobian
as well as of the eigenvalues of the covariance operator, together with some
regularity assumptions regarding their relative rate of convergence. An
explicit example is given regarding an electromagnetic inverse source problem
with "external" spherically isotropic noise, as well as "internal" additive
uncorrelated noise.Comment: Submitted to Journal of Mathematical Physic
Light Baryon Resonances: Restrictions and Perspectives
The problem of nucleon resonances N' with masses below the Delta is
considered. We derive bounds for the properties of such states. Some of these
are new, while others improve upon existing limits. We discuss the nature of N'
states, and their unitary partners, assuming their existence can be verified.Comment: 11 pages, 11 figur
Calculus and heat flow in metric measure spaces and applications to spaces with Ricci bounds from below
This paper is devoted to a deeper understanding of the heat flow and to the
refinement of calculus tools on metric measure spaces (X,d,m). Our main results
are:
- A general study of the relations between the Hopf-Lax semigroup and
Hamilton-Jacobi equation in metric spaces (X,d).
- The equivalence of the heat flow in L^2(X,m) generated by a suitable
Dirichlet energy and the Wasserstein gradient flow of the relative entropy
functional in the space of probability measures P(X).
- The proof of density in energy of Lipschitz functions in the Sobolev space
W^{1,2}(X,d,m).
- A fine and very general analysis of the differentiability properties of a
large class of Kantorovich potentials, in connection with the optimal transport
problem.
Our results apply in particular to spaces satisfying Ricci curvature bounds
in the sense of Lott & Villani [30] and Sturm [39,40], and require neither the
doubling property nor the validity of the local Poincar\'e inequality.Comment: Minor typos corrected and many small improvements added. Lemma 2.4,
Lemma 2.10, Prop. 5.7, Rem. 5.8, Thm. 6.3 added. Rem. 4.7, Prop. 4.8, Prop.
4.15 and Thm 4.16 augmented/reenforced. Proof of Thm. 4.16 and Lemma 9.6
simplified. Thm. 8.6 corrected. A simpler axiomatization of weak gradients,
still equivalent to all other ones, has been propose
Correlator Bank Detection of GW chirps. False-Alarm Probability, Template Density and Thresholds: Behind and Beyond the Minimal-Match Issue
The general problem of computing the false-alarm rate vs. detection-threshold
relationship for a bank of correlators is addressed, in the context of
maximum-likelihood detection of gravitational waves, with specific reference to
chirps from coalescing binary systems. Accurate (lower-bound) approximants for
the cumulative distribution of the whole-bank supremum are deduced from a class
of Bonferroni-type inequalities. The asymptotic properties of the cumulative
distribution are obtained, in the limit where the number of correlators goes to
infinity. The validity of numerical simulations made on small-size banks is
extended to banks of any size, via a gaussian-correlation inequality. The
result is used to estimate the optimum template density, yielding the best
tradeoff between computational cost and detection efficiency, in terms of
undetected potentially observable sources at a prescribed false-alarm level,
for the simplest case of Newtonian chirps.Comment: submitted to Phys. Rev.
HtrA Protease from Bacillus subtilis Suppresses the Bacterial Fouling of the Rat Skin Injuries
© 2016, Springer Science+Business Media New York.The gene of serine protease HtrA from Bacillus subtilis was cloned and recombinant protein was overexpressed in E. coli and purified. The recombinant HtrA efficiently suppressed in vitro the biofilm formation by clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis. While the model rat skin injuries treated with HtrA healed slower than in the case of chymotrypsin, their recovery was significantly faster compared with pure buffer. On the other hand, the number of bacterial CFUs on the injuries treated with HtrA solution was reduced five times in 8 days, similarly to chymotrypsin-treated ones, while only twofold reduction was observed in controls. By the way, the resident microflora content of protease-treated and control wounds remained almost similar within 4 days, with Enterococcus faecalis and S. epidermidis being the main resident microflora after the treatment. To the eighth day, the amount of staphylococcal cells was drastically reduced on HtrA- and chymotrypsin-treated wound surfaces, confirming that both proteases provide wound cleaning from pathogenic microflora. Thus, HtrA from B. subtilis significantly reduces the microbial fouling of the wound surface being thereby of interest for wound care
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