558 research outputs found
Effect of hydroalcoholic Zingiber extract on creatinine and blood urea nitrogen (BUN) of mice.
چکیده: زمینه و هدف: اکثر جمعیت جهان به خصوص در کشورهای در حال توسعه، برای احتیاجات اساسی بهداشتی خود از داروهای گیاهی استفاده می کنند. زنجبیل (Zingiber officinale Roscoe) یک چاشنی غذایی می باشد که از دو هزار سال پیش به عنوان دارو در طب چینی، پزشکی سنتی ایران و طب اسلامی استفاده شده است. از آنجایی که افزایش اوره سرم و سطوح کرآتینین در آزمایش های کلینیکی بیانگر نارسایی کلیوی می باشد، این مطالعه با هدف بررسی تأثیر عصاره هیدروالکلی زنجبیل بر نیتروژن اوره خون و کرآتینین به منظور ارزیابی عملکرد کلیه انجام شد. روش بررسی: در یک مطالعه تجربی عصاره هیدروالکلی زنجبیل به صورت یک روز در میان در یک دوره 20 روزه با دوزهای 10، 20 و 40 میلی گرم بر کیلوگرم در 48 ساعت به صورت داخل صفاقی به موشهای نر آزمایشگاهی تزریق شد. سپس خونگیری با استفاده از روش پانکسیون سینوس چشمی انجام و میزان نیتروژن اوره خون (BUN) و کراتینین اندازه گیری شد. داده ها با استفاده از آزمون های آنالیز واریانس یک طرفه و کروسکال والیس تجزیه و تحلیل شد. یافته ها: میانگین غلظت BUN در گروه کنترل 89/3±68/37 و در گروههای دریافت کننده 10، 20 و 40 میلی گرم بر کیلوگرم در 48 ساعت زنجبیل به ترتیب 38/11±54/21 (05/0
The protective effect of garlic extract on diabetic nephropathy
Diabetes causes significant changes in urine and serum constituents such as albumin, creatinine, urea nitrogen, and glycated hemoglobin. Garlic extract, however, has been shown to restore all of these biochemicals, and cause histopathological changes. Administration of garlic extract or metformin, or their combinations has also been demonstrated to have both curative and protective effects against gentamicin nephrotoxicity. These findings can potentiate the clinical use of combinations of metformin and garlic extract in the prevention of diabetic nephropathy
Hyperuricemia aggravates IgA nephropathy
It is well documented that hyperuricemia is an independent risk factor for IgA nephropathy, and appropriate treatment by allopurinol is a reasonable modality in the patients. We believe that, this drug should routinely be included to the treatment of patients with IgA nephropathy. In this regard, to better understand the allopurinol kidney protective properties in IgA nephropathy, clinical studies are suggested
A Comparative Study of Different Phase Detrending Algorithms for Scintillation Monitoring
Rapid and sudden fluctuations of phase and amplitude in Global Navigation Satellite System (GNSS) signals due to diffraction of the ionosphere phase components when signals passing through small-scale irregularities (less than hundreds meters) are commonly so-called ionospheric scintillation. The aim of the paper is to analyze the implementation and compare the performance of different phase detrending algorithms to improve scintillation monitoring. Three different phase detrending methods, namely, three cascaded second-order high pass filters, six order Butterworth filter conducted by cascading six first-order high pass Butterworth filters, and Fast Iterative Filter (FIF) are considered in this paper. The study exploits real GNSS signals (GPS L1, Galileo E1b) affected by significant phase scintillation effects, collected in early September 2017 at Brazilian Centro de Radioastronomia e Astrofisica Mackenzie (CRAAM) monitoring station and at Adventdalen (Svalbard, Norway) research station. In this study, a software defined radio (SDR) based GNSS receiver is used to process GNSS signals and to implement the aforementioned detrending algorithms
Dynamics of levitated nanospheres: towards the strong coupling regime
The use of levitated nanospheres represents a new paradigm for the
optomechanical cooling of a small mechanical oscillator, with the prospect of
realising quantum oscillators with unprecedentedly high quality factors. We
investigate the dynamics of this system, especially in the so-called
self-trapping regimes, where one or more optical fields simultaneously trap and
cool the mechanical oscillator. The determining characteristic of this regime
is that both the mechanical frequency and single-photon
optomechanical coupling strength parameters are a function of the optical
field intensities, in contrast to usual set-ups where and are
constant for the given system. We also measure the characteristic transverse
and axial trapping frequencies of different sized silica nanospheres in a
simple optical standing wave potential, for spheres of radii \,nm,
illustrating a protocol for loading single nanospheres into a standing wave
optical trap that would be formed by an optical cavity. We use this data to
confirm the dependence of the effective optomechanical coupling strength on
sphere radius for levitated nanospheres in an optical cavity and discuss the
prospects for reaching regimes of strong light-matter coupling. Theoretical
semiclassical and quantum displacement noise spectra show that for larger
nanospheres with \,nm a range of interesting and novel dynamical
regimes can be accessed. These include simultaneous hybridization of the two
optical modes with the mechanical modes and parameter regimes where the system
is bistable. We show that here, in contrast to typical single-optical mode
optomechanical systems, bistabilities are independent of intracavity intensity
and can occur for very weak laser driving amplitudes
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