The strength of nuclear shell effects at N=126 in the r-process region

We have investigated nuclear shell effects across the magic number N=126 in the region of the r-process path. Microscopic calculations have been performed using the relativistic Hartree-Bogoliubov approach within the framework of the RMF theory for isotopic chains of rare-earth nuclei in the r-process region. The Lagrangian model NL-SV1 with the inclusion of the vector self-coupling of omega meson has been employed. The RMF results show that the shell effects at N=126 remain strong and exhibit only a slight reduction in the strength in going from the r-process path to the neutron drip line. This is in striking contrast to a systematic weakening of the shell effects at N=82 in the r-process region predicted earlier in the similar approach. In comparison the shell effects with microscopic-macroscopic mass formulae show a near constancy of shell gaps leading to strong shell effects in the region of r-process path to the drip line. A recent analysis of solar-system r-process abundances in a prompt supernova explosion model using various mass formulae including the recently introduced mass tables based upon HFB approach shows that whilst mass formulae with weak shell effects at N=126 give rise to a spread and an overproduction of nuclides near the third abundance peak at A~190, mass tables with droplet models showing stronger shell effects are able to reproduce the abundance features near the third peak appropriately. In comparison, several analyses of the second r-process peak at A~130 have required weakened shell effects at N=82. Our predictions in the RMF theory with NL-SV1, which exhibit weaker shell effects at N=82 and stronger one at N=126 in the r-process region, support the conjecture that a different nature of the shell effects at the magic numbers may be at play in r-process nucleosynthesis of heavy nuclei.Comment: 14 pages, 8 figures; submitted to Physical Review C. Part of this work was presented at Nuclear Physics in Astrophysics II, 20th International Nuclear Physics Divisional Conference of the European Physical Society, at Debrecen, Hungary, May 16-20, 200

Neutrino-induced fission of neutron-rich nuclei

We calculate neutrino-induced fission cross sections for selected nuclei with Z=84-92. We show that these reactions populate the daughter nucleus at excitation energies where shell effects are significantly washed out, effectively reducing the fission barrier. If the r-process occurs in the presence of a strong neutrino fluence, and electron neutrino average energies are sufficiently high, perhaps as a result of matter-enhanced neutrino flavor transformation, then neutrino-induced fission could lead to significant alteration in the r-process flow in slow outflow scenarios.Comment: 4 pages, three figure

Molecular Characterization of \u3ci\u3eCitrus tatter leaf virus\u3c/i\u3e Historically Associated with Meyer Lemon Trees: Complete Genome Sequence and Development of Biologically Active In Vitro Transcripts

Citrus tatter leaf virus isolated from Meyer lemon trees (CTLV-ML) from California and Florida induces bud union incompatibility of citrus trees grafted on the widely used trifoliate and trifoliate hybrid rootstocks. The complete genome sequence of CTLV-ML was determined to be 6,495 nucleotides (nts), with two overlapping open reading frames (ORFs) and a poly (A) tail at the 3′ end. The genome organization is similar to other capilloviruses, with ORF1 (nts 37 to 6,354) encoding a putative 242-kDa polyprotein which contains replication-associated domains plus a coat protein (CP), and ORF2 (nts 4,788 to 5,750), which is located within ORF1 in a different reading frame and encodes a putative movement protein. Although the proteins encoded by CTLV-ML possesses 84 to 96% amino acid sequence identity with strains of Apple stem grooving virus (ASGV), we observed two strikingly different regions in ORF1: variable region I (amino acids 532 to 570) and variable region II (amino acids 1,583 to 1,868), with only 15 to 18 and 56 to 62% identities, respectively, with the corresponding regions of ASGV strains. Conditions for a herbaceous systemic assay host were optimized in which the wildtype virus induced systemic infection in Phaseolus vulgaris cv. Light Red Kidney (LRK) bean plants at 19 or 22°C but not at higher temperatures. In vitro transcripts generated from full-length cDNA clones induced systemic symptoms on LRK bean plants similar to that of the wild-type virus. Replication of the recombinant virus was confirmed by hybridization of a 5′ positive-stranded RNA-specific probe to a genome-sized RNA and by reverse-transcription polymerase chain reaction

Phase shift experiments identifying Kramers doublets in a chaotic superconducting microwave billiard of threefold symmetry

The spectral properties of a two-dimensional microwave billiard showing threefold symmetry have been studied with a new experimental technique. This method is based on the behavior of the eigenmodes under variation of a phase shift between two input channels, which strongly depends on the symmetries of the eigenfunctions. Thereby a complete set of 108 Kramers doublets has been identified by a simple and purely experimental method. This set clearly shows Gaussian unitary ensemble statistics, although the system is time-reversal invariant.Comment: RevTex 4, 5 figure

Confinement in the Deconfined Phase: A numerical study with a cluster algorithm

We have previously found analytically a very unusual and unexpected form of confinement in SU(3) Yang-Mills theory. This confinement occurs in the deconfined phase of the theory. The free energy of a single static test quark diverges, even though it is contained in deconfined bulk phase and there is no QCD string present. This phenomenon occurs in cylindrical volumes with a certain choice of spatial boundary conditions. We examine numerically an effective model for the Yang-Mills theory and, using a cluster algorithm, we observe this unusual confinement. We also find a new way to determine the interface tension of domain walls separating distinct bulk phases.Comment: LaTex, 14 pages, 4 figure

Signal Transduction Pathways in the Pentameric Ligand-Gated Ion Channels

The mechanisms of allosteric action within pentameric ligand-gated ion channels (pLGICs) remain to be determined. Using crystallography, site-directed mutagenesis, and two-electrode voltage clamp measurements, we identified two functionally relevant sites in the extracellular (EC) domain of the bacterial pLGIC from Gloeobacter violaceus (GLIC). One site is at the C-loop region, where the NQN mutation (D91N, E177Q, and D178N) eliminated inter-subunit salt bridges in the open-channel GLIC structure and thereby shifted the channel activation to a higher agonist concentration. The other site is below the C-loop, where binding of the anesthetic ketamine inhibited GLIC currents in a concentration dependent manner. To understand how a perturbation signal in the EC domain, either resulting from the NQN mutation or ketamine binding, is transduced to the channel gate, we have used the Perturbation-based Markovian Transmission (PMT) model to determine dynamic responses of the GLIC channel and signaling pathways upon initial perturbations in the EC domain of GLIC. Despite the existence of many possible routes for the initial perturbation signal to reach the channel gate, the PMT model in combination with Yen's algorithm revealed that perturbation signals with the highest probability flow travel either via the β1-β2 loop or through pre-TM1. The β1-β2 loop occurs in either intra- or inter-subunit pathways, while pre-TM1 occurs exclusively in inter-subunit pathways. Residues involved in both types of pathways are well supported by previous experimental data on nAChR. The direct coupling between pre-TM1 and TM2 of the adjacent subunit adds new insight into the allosteric signaling mechanism in pLGICs. © 2013 Mowrey et al

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC

While the pentameric ligand-gated ion channel ELIC has recently provided first insight into the architecture of the family at high resolution, its detailed investigation was so far prevented by the fact that activating ligands were unknown. Here we describe a study on the functional characterization of ELIC by electrophysiology and X-ray crystallography. ELIC is activated by a class of primary amines that include the neurotransmitter GABA at high micro- to millimolar concentrations. The ligands bind to a conserved site and evoke currents that slowly desensitize over time. The protein forms cation selective channels with properties that resemble the nicotinic acetylcholine receptor. The high single channel conductance and the comparably simple functional behavior make ELIC an attractive model system to study general mechanisms of ion conduction and gating in this important family of neurotransmitter receptors

Persistent Infection and Promiscuous Recombination of Multiple Genotypes of an RNA Virus within a Single Host Generate Extensive Diversity

Recombination and reassortment of viral genomes are major processes contributing to the creation of new, emerging viruses. These processes are especially significant in long-term persistent infections where multiple viral genotypes co-replicate in a single host, generating abundant genotypic variants, some of which may possess novel host-colonizing and pathogenicity traits. In some plants, successive vegetative propagation of infected tissues and introduction of new genotypes of a virus by vector transmission allows for viral populations to increase in complexity for hundreds of years allowing co-replication and subsequent recombination of the multiple viral genotypes. Using a resequencing microarray, we examined a persistent infection by a Citrus tristeza virus (CTV) complex in citrus, a vegetatively propagated, globally important fruit crop, and found that the complex comprised three major and a number of minor genotypes. Subsequent deep sequencing analysis of the viral population confirmed the presence of the three major CTV genotypes and, in addition, revealed that the minor genotypes consisted of an extraordinarily large number of genetic variants generated by promiscuous recombination between the major genotypes. Further analysis provided evidence that some of the recombinants underwent subsequent divergence, further increasing the genotypic complexity. These data demonstrate that persistent infection of multiple viral genotypes within a host organism is sufficient to drive the large-scale production of viral genetic variants that may evolve into new and emerging viruses