32 research outputs found
The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres
Get PDFINCENP acts as a protein scaffold that integrates the functions of two crucial mitotic kinases, Aurora B and Polo, at centromeres of mitotic chromosomes
The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres
Get PDFINCENP acts as a protein scaffold that integrates the functions of two crucial mitotic kinases, Aurora B and Polo, at centromeres of mitotic chromosomes
The cellular geography of Aurora kinases
Get PDFAurora is the name given to a family of highly conserved protein kinases with essential roles in
many aspects of cell division. Yeasts have a single Aurora kinase, whereas mammals have three:
Aurora A, B and C. During mitosis, Aurora kinases regulate the structure and function of the cytoskeleton and chromosomes and the interactions between these two at the kinetochore.
They also regulate signalling by the spindle-assembly checkpoint pathway and cytokinesis.
Perturbation of Aurora kinase expression or function might lead to cancer
Chromatin-associated Protein Phosphatase I Regulates Aurora-B and Histone H3 Phosphorylation
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Informing the Pedagogical Practice of Interreligious Education: Critical Social Science Directions
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