Wavelet-based methodology for [15O]-H20 PET brain activation assessment

[Abstract] AMI International Conference 2003, September 21-27, Madrid, Spain: "High Resolution Molecular Imaging: from Basic Science to Clinical Applications"Statistical parametric mapping (SPM) is a voxel-byvoxel analysis method commonly used for the detection of brain activation patterns. An alternative approach is the use of multiscale information by means of wavelet analysis. In this study, we have compared the detection of brain activations using conventional SPM and a statistical wavelet analysis in a set of realistic simulated [15O]-H20 positron emission tomography (PET) phantomsPublicad

Effect of different interpolation methods on the accuracy of the reconstruction of spiral k-space trajectories in MRI

[Poster] 4th European Molecular Imaging Meeting, Barcelona, Spain, May 27 - 30, 2009This work is supported in part by the projects CdTeaM (CeniT-ingenio 2010), Ministerio de Ciencia e innovación, and Ciber Cb07/09/0031 CiberSaM, Ministerio de Sanidad y Consumo.Publicad

FDG-PET studies of the effect of MDMA in rat brain

[Abstract] The 10th International Conference on Functional Mapping of the Human Brain, June 13-17, 2004, Budapest, HungaryAlterations of the human brain due to MDMA use are a focus of ongoing research. MDMA abuse produces both short and long-term effects on brain; MDMA-induced functional alterations of the serotonergic system are reported to alter local energy metabolism of cortical and subcortical structures. Presently, there are no FDG-PET experimental studies reported in animals. The aim of this study is to assess these brain glucose metabolism changes after a single dose of MDMA in rats by using FDG-PETPublicad

Detection of small murine lung tumours by FDG-PET

[Abstract] AMI International Conference 2003, September 21 - 27, Madrid, Spain: "High Resolution Molecular Imaging: from Basic Science to Clinical Applications"The functional information provided by 2-deoxy-2- [18F]fluoro-D-Glucose (FDG) positron emission tomography (PET) is commonly used to detect primary tumours and metastases in clinical studies. The aim of this work is to assess the possibilities of FDG-PET studies to detect small lung tumour lesions in mice, using a dedicated small animal PET scannerPublicad

Fat composition assessment by 1H and 13C spectroscopy in mice

Proceeding of: 17th Scientific Meeting, International Society for Magnetic Resonance in Medicine, 18-24 April, 2009, Honolulu, Hawai, US

A new algorithm for ring artifact reduction in cone-beam computed tomography: preliminary results

[Abstract] 22nd International Congress and Exhibition, Barcelona, Spain, June 25-28, 2008In this work we present a new method for ring artifact compensation, suitable for cone beam data. Starting from the idea of Sijbers et al., we have developed an improved procedure that operates on the projection data before the reconstruction and does not require interpolations, thus avoiding image degradation and reducing the computational burden. Results on phantoms and rodent studies are presentedPublicad

Optimization of 2-DEOXY-2-[18F] FLUORO-D-GLUCOSE positron emission tomography thorax imaging of laboratory small animals

[Abstract] AMI Annual Conference 2005, March 18-23, Orlando, FloridaThe search of oncologic lesions in thorax may be hindered by the high uptake of organs such as the heart or back muscles that prevent the proper visualization of neighbor organs. The aim of this study is to analyze to what extent glucose metabolism can be modulated to obtain an optimal thorax image in micePublicad