A note on minimal resolutions of vector-spread Borel ideals

We consider vector-spread Borel ideals. We show that these ideals have linear quotients and thereby we determine the graded Betti numbers and the bigraded Poincaré series. A characterization of the extremal Betti numbers of such a class of ideals is given. Finally, we classify all Cohen-Macaulay vector-spread Borel ideals

Optimization of a Green Extraction of Polyphenols from Sweet Cherry (Prunus avium L.) Pulp

This work focused on the optimization of the ultrasound (US) extraction of polyphenols from sweet cherry pulp by monitoring cyanidin-3O-rutinoside, quercetin-3O-rutinoside, and trans-3-O-coumaroylquinic acid, representing the main anthocyanin, flavonol, and hydroxycinnamate, respectively, identified in the extracts through chromatographic analyses (HPLC-DAD), as output variables. The optimization was performed following a two-level central composite design and the influence of the selected independent variables (i.e., extraction time and solid to solvent ratio) was checked through the response surface methodology. The maximum recovery of the phenolic compounds was obtained at 3 min and 0.25 g/mL in water/ethanol (1:1, v/v) at a set temperature (25 °C), sonication power (100 W), and sonication frequency (37 kHz). Subsequent validation experiments proved the effectiveness and reliability of the gathered mathematical models in defining the best ultrasound-assisted extraction conditions

Olive sound: A sustainable radical innovation

Olive Sound is the acronym of a Horizon 2020 European Project aimed at the development of a high-flow oil extraction plant, the Sono-Heat-Exchanger, which combines ultrasound and heat exchange in order to break, through a radical innovation model in the oil mill, the historical paradigm that sees as inversely correlated the oil yield and the content of bio-phenols. These compounds are biologically active molecules that transform the product, extra virgin olive oil, from a mere condiment into a functional food. The primary objective of the project, financially supported by the European Union through the “Fast Track to Innovation” program, is the development of a product “ready for the market” (TRL 9) capable of making the involved companies more competitive while increasing the competitiveness of European extra virgin olive oil in the international context

Hemp: An Alternative Source for Various Industries and an Emerging Tool for Functional Food and Pharmaceutical Sectors

Hemp is a high-value crop that originated in Central Asia and is a historic but emerging cultivated plant. It may be grown for fiber, food, paper making, textiles, and therapeutic reasons. In the 21st century, market interest in hemp and its products has notably increased because seed portions can be utilized in the agri-food business, the woody component of the stem can be used in green buildings, the outer layer of the stems can be used in the textile industry, and the extraction of bioactive components from roots can play a vital role in the pharmacological industries. Hemp has recently been demonstrated to be a viable alternative for economies built on synthetic materials by the food, pharmaceutical, textiles, paper, building, and energy industries, among others. As a result, the goal of this study is to assemble the significant advancements in hemp, as well as to identify research gaps and research direction opportunities. The hemp plant will be provided more encouragement to be grown and be used. Many applications of hemp may be pushed to the next level for both producing a green environment and profit. A strong vision and a well-defined plan will pave the path for the discovery of new technologies and concepts

‘Malvasia nera di Brindisi/Lecce’ grapevine cultivar (Vitis vinifera L.) originated from ‘Negroamaro’ and ‘Malvasia bianca lunga’

‘Malvasia nera di Brindisi’ and ‘Malvasia nera di Lecce’ are two of the few Malvasias with black berries and belong to the Apulian ampelographic assortment (South Italy). Their presumed synonymy has been recently ascertained with SSR markers and therefore these two black 'Malvasias' can be considered as an unique variety. We discovered that this cultivar is the cross between ‘Malvasia bianca lunga’ alias ‘Malvasia del Chianti’ and ‘Negroamaro’ by using 42 nuclear SSR. Both parents belong to the Apulian varietal resources, since centuries. So far, ‘Malvasia nera di Brindisi/Lecce’ origin has been obscure; now we may assert that this cultivar was born right in Apulia. Three sets of chloroplast SSR loci were used to determine the female and the male parent: 6 ccmp loci, already used in previous pedigree studies, 15 ccSSR loci and 2 NTCP loci, derived from tobacco. The second set of loci was sequenced in order to compare the length of the markers with the reference species where they were originally obtained: in 4 cases no microsatellite motives were detected and in other 4 cases the perfect repetition found in tobacco was not maintained in grape. Unfortunately, the three sets of markers failed to show any polymorphism. A detailed comparison of the black Malvasia morphology with its two parents showed a closer similarity to ‘Negroamaro’. Also the anthocyanin profile is in agreement with that of the black parent; its varietal aroma presents interesting levels of free and bound 2-phenylethanol, responsible for rose flavor, and of bound linalool compounds.

Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury.

Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocardial function, yet exact mechanisms remain unclear. Impaired autophagy leads to heart failure and mitophagy is important for mitigating ischemia/reperfusion injury. This study aims to investigate whether the beneficial effects of therapeutic hypothermia are due to preserved autophagy and mitophagy. Under general anesthesia, the left anterior descending coronary artery of 19 female farm pigs was occluded for 90 minutes with consecutive reperfusion. 30 minutes after reperfusion, we performed pericardial irrigation with warm or cold saline for 60 minutes. Myocardial tissue analysis was performed one and four weeks after infarction. Therapeutic hypothermia induced a significant increase in autophagic flux, mitophagy, mitochondrial mass and function in the myocardium after infarction. Cell stress, apoptosis, inflammation as well as fibrosis were reduced, with significant preservation of systolic and diastolic function four weeks post infarction. We found similar biochemical changes in human samples undergoing open chest surgery under hypothermic conditions when compared to the warm. These results suggest that autophagic flux and mitophagy are important mechanisms implicated in cardiomyocyte recovery after myocardial infarction under hypothermic conditions. New therapeutic strategies targeting these pathways directly could lead to improvements in prevention of heart failure

Improved Cu2O/AZO Heterojunction by Inserting a Thin ZnO Interlayer Grown by Pulsed Laser Deposition

Cu2O/ZnO:Al (AZO) and Cu2O/ZnO/AZO heterojunctions have been deposited on glass substrates by a unique three-step pulsed laser deposition process. The structural, optical, and electrical properties of the oxide films were investigated before their implementation in the final device. X-ray diffraction analysis indicated that the materials were highly crystallized along the c-axis. All films were highly transparent in the visible region with enhanced electrical properties. Atomic force and scanning electron microscopies showed that the insertion of a ZnO layer between the Cu2O and AZO films in the heterojunction enhanced the average grain size and surface roughness. The heterojunctions exhibited remarkable diode behavior and good rectifying character with low leakage current under reverse bias. The presence of the ZnO interlayer film significantly reduced the parasitic and leakage currents across the barrier, improved the quality of the heterostructure, made the energy band between AZO and Cu2O layers smoother, and eliminated the possibility of interface recombination, leading to much longer electron lifetime

Is the dependence on the temperature of the friction important in stress triggering phenomena? The case of the 2000 Iceland seismic sequence

We perform numerical experiments by using a mass–spring fault model subject to an external coseismic stress perturbation due to a remote seismic event happening on another fault, the causative fault. In particular, the aim of this study is to investigate the instantaneous fault interaction and possible triggering that happens when a fault perturbed by a stress change fails before the so–called unperturbed instability. As a realistic example we focus our attention on the instantaneous dynamic triggering phenomena occurred during the 17 June 2000 south Iceland seismic sequence in the South Iceland Seismic Zone (SISZ, Reykjanes Peninsula). The main event (Ms 6.6) was followed by three large events within a few tens of seconds (8, 26 and 30 s, respectively) located in a neighborhood of several tens of km. Among them the 26 s event was the best constrained (Bizzarri and Belardinelli, 2008). In the present study, conditions to simulate the instantaneous dynamic triggering connected to the former three events, have been investigated using the simple 1–D spring–slider analogue model representing a fault governed by the rate– and state–dependent friction laws. In previous studies suitable constitutive parameters of the modeled fault which allow the instantaneous triggering of the three events, have been found (Antonioli et al., 2006) and, furthermore, it was also shown how the dynamics of the 26 s event strongly depends on the assumed constitutive law and stress conditions (Bizzarri and Belardinelli, 2008) by considering the Dieterich–Ruina (DR henceforth) and the Ruina–Dieterich (RD henceforth) governing laws. In this context take place the present study original contribution that is to better understand if the conditions of instantaneous dynamic triggering (focusing on the case of the 26 s triggered event) provide any significant differences if modeled with a different rate– and state–dependent governing equation, the Chester and Higgs law (CH henceforth; see Chester and Higgs, 1992; Bizzarri, 2010b; Bizzarri, 2010c) which accounts for the thermal effect for frictional heating which may occur during seismic sliding