8 research outputs found
Physicochemical characterization and structural evaluation of a specific 2:1 cocrystal of naproxen-nicotinamide
研究科: 千葉大学大学院医学薬学府学位:千大院医薬博甲第薬148号博士(薬学)千葉大
第1301回千葉医学会例会・臓器制御外科学教室談話会
In house GI-tract-specific database enriched with genes involved in GI-tract development, morphogenesis and acid secretion. Protein name, Symbol, Accession number (no.), Organism and Biological role (when associated) are shown. (XLSX 24 kb
Supplemental Materials: Risks and Benefits of Consumption of Great Lakes Fish
Background: Beneficial effects of fish consumption on early cognitive development and cardiovascular health have been attributed to the omega-3 fatty acids in fish and fish oils, but toxic chemicals in fish may adversely affect these health outcomes. Risk–benefit assessments of fish consumption have frequently focused on methylmercury and omega-3 fatty acids, not persistent pollutants such as polychlorinated biphenyls, and none have evaluated Great Lakes fish consumption.
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jectives: The risks and benefits of fish consumption have been established primarily for marine fish. Here, we examine whether sufficient data are available to evaluate the risks and benefits of eating freshwater fish from the Great Lakes.
Methods: We used a scoping review to integrate information from multiple state, provincial, and federal agency sources regarding the contaminants and omega-3 fatty acids in Great Lakes fish and fish consumers, consumption rates and fish consumption advisories, and health effects of contaminants and omega-3 fatty acids.
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ata synthesis: Great Lakes fish contain persistent contaminants—many of which have documented adverse health effects —that accumulate in humans consuming them. In contrast, data are sparse on omega-3 fatty acids in the fish and their consumers. Moreover, few studies have documented the social and cultural benefits of Great Lakes fish consumption, particularly for subsistence fishers and native communities. At this time, federal and state/provincial governments provide fish consumption advisories based solely on risk.
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onclusions: Our knowledge of Great Lakes fish has critical gaps, particularly regarding the benefits of consumption. A risk–benefit analysis requires more information than is currently available on the concentration of omega-3 fatty acids in Great Lakes fish and their absorption by fish eaters in addition to more information on the social, cultural, and health consequences of changes in the amount of fish consumed
Additional file 4: of The transcriptome of metamorphosing flatfish
Annotation of the head transcriptome. Contig ID, transcript name, number of GOs and their description and enzymatic codes are shown for each contig. (XLSX 4280 mb
Additional file 2: of The transcriptome of metamorphosing flatfish
Annotation of the skin transcriptome. Contig ID, transcript name, number of GOs and their description and enzymatic codes are shown for each contig. (XLSX 3090 kb
Additional file 8: of The transcriptome of metamorphosing flatfish
Significantly overrepresented Biological Process GO terms identified for the head transcriptome (FDR < 0.05). (DOC 116 kb
Additional file 2: of Intergenic disease-associated regions are abundant in novel transcripts
Supplementary figures and Tables S1 to S9. (DOCX 4403 kb