Study on high performance insulation thermal design criteria Quarterly progress report

Diffusion coefficients, outgassing studies, and correlation of complete system thermal model computer program predictions with 82.6 inch tank test dat

Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom.

Takayasu arteritis (TA) is an idiopathic large-vessel vasculitis affecting the aorta and its major branches. Although the disease rarely affects children, it does occur, even in infants. The objective of this study was to evaluate the clinical features, disease activity, treatment and outcome of childhood TA in a tertiary UK centre

A critical analysis of the review on antimicrobial resistance report and the infectious disease financing facility

Over the past year, two major policy initiatives have been introduced focusing on stimulating antibiotic development for human consumption. The European Investment Bank has announced the development of the Infectious Disease Financing Facility (IDFF) and the British government commissioned the Review on Antimicrobial Resistance, led by Jim O’Neill. Each constitutes a major effort by the European community to address the evolving crisis of antimicrobial resistance. Though both have similar goals, the approaches are unique and worthy of consideration. This manuscript utilizes a previously published framework for evaluation of antibiotic incentive plans to clearly identify the strengths and weaknesses of each proposal. The merits of each proposal are evaluated in how they satisfy four key objectives: 1) Improve the overall net present value (NPV) for new antibiotic projects; 2) Enable greater participation of Small to Medium Sized Enterprises (SME); 3) Encourage participation by large pharmaceutical companies; 4) Facilitate cooperation and synergy across the antibiotic market. The IDFF seeks to make forgivable loans to corporations with promising compounds, while the O’Neill group proposes a more comprehensive framework of early stage funding, along with the creation of a stable global market. Ultimately, the proposals may prove complementary and if implemented together may form a more comprehensive plan to address an impending global crisis. Substantial progress will only be made on these efforts if action is taken at an international level, therefore we recommend consideration of these efforts at the upcoming G20 summit

Spatial Variations in Galactic H I Structure on AU-Scales Toward 3C 147 Observed with the Very Long Baseline Array

This paper reports dual-epoch, Very Long Baseline Array observations of H I absorption toward 3C 147. One of these epochs (2005) represents new observations while one (1998) represents the reprocessing of previous observations to obtain higher signal-to-noise results. Significant H I opacity and column density variations, both spatially and temporally, are observed with typical variations at the level of \Delta\tau ~ 0.20 and in some cases as large as \Delta\tau ~ 0.70, corresponding to column density fluctuations of order 5 x 10^{19} cm^{-2} for an assumed 50 K spin temperature. The typical angular scale is 15 mas; while the distance to the absorbing gas is highly uncertain, the equivalent linear scale is likely to be about 10 AU. Approximately 10% of the face of the source is covered by these opacity variations, probably implying a volume filling factor for the small-scale absorbing gas of no more than about 1%. Comparing our results with earlier results toward 3C 138 (Brogan et al.), we find numerous similarities, and we conclude that small-scale absorbing gas is a ubiquitous phenomenon, albeit with a low probability of intercept on any given line of sight. Further, we compare the volumes sampled by the line of sight through the Galaxy between our two epochs and conclude that, on the basis of the motion of the Sun alone, these two volumes are likely to be substantially different. In order to place more significant constraints on the various models for the origin of these small-scale structures, more frequent sampling is required in any future observations.Comment: 16 pages with 10 figures in 24 files; AASTeX format; accepted by A

Study of cryogenic container thermodynamics during propellant transfer

Study of thermodynamic phenomena occurring during transfer of cryogenic liquids from dewar to receiver tank reveals that the basic cause of tank implosion is evaporation rate of droplets entering the tank in the early transfer phase. Analyses of the thermodynamics involved and implosion prevention techniques are included