Pathomorphological Changes in Poultry Pasteurellios, Pullorosis and Colibacteriosis Diseases

The organism of chicken infected with individual pathogens exhibits relatively simple patho-anatomical modifications in the presence of two or three separate bacterial pathogens. Because it is highly challenging to differentiate between mixed bacterial infections based just on clinical symptoms, pathologoanatomical examination and distinction are preferred. These disorders will be accurately diagnosed promptly and without delay if the pathologo-anatomical investigations are properly examined, and preventive measures will be consistently applied

On the temperature dependence of ballistic Coulomb drag in nanowires

We have investigated within the theory of Fermi liquid dependence of Coulomb drag current in a passive quantum wire on the applied voltage $V$ across an active wire and on the temperature $T$ for any values of $eV/k_BT$. We assume that the bottoms of the 1D minibands in both wires almost coincide with the Fermi level. We come to conclusions that 1) within a certain temperature interval the drag current can be a descending function of the temperature $T$; 2) the experimentally observed temperature dependence $T^{-0.77}$ of the drag current can be interpreted within the framework of Fermi liquid theory; 3) at relatively high applied voltages the drag current as a function of the applied voltage saturates; 4) the screening of the electron potential by metallic gate electrodes can be of importance.Comment: 7 pages, 1 figur

Rapid Non-Destructive Prediction of Water Activity in Dry-Cured Meat

Water activity (aw) describes the amount of free water available in a matrix for growth of microbiological pathogens and spoilage flora. It is used to predict the safety of food products, and has particular importance for dry-cured meat manufacturers. Results from tests on dry-cured pork (n = 83) demonstrate a high degree of correlation (R2 = 0.909) with current industry standard equipment. System accuracy at the 95% confidence interval (0.0125) is comparable with existing equipment available to industry. However, the added advantage of the microwave sensor to enable rapid and non-destructive measurement means that it could be used for day-to-day monitoring and optimization of products within the dry-cured meat value chain. This would reduce per-product operating costs and waste, in addition to facilitating recipe development (e.g., reduced salt)

Coulomb drag between ballistic one-dimensional electron systems

The presence of pronounced electronic correlations in one-dimensional systems strongly enhances Coulomb coupling and is expected to result in distinctive features in the Coulomb drag between them that are absent in the drag between two-dimensional systems. We review recent Fermi and Luttinger liquid theories of Coulomb drag between ballistic one-dimensional electron systems, and give a brief summary of the experimental work reported so far on one-dimensional drag. Both the Fermi liquid (FL) and the Luttinger liquid (LL) theory predict a maximum of the drag resistance R_D when the one-dimensional subbands of the two quantum wires are aligned and the Fermi wave vector k_F is small, and also an exponential decay of R_D with increasing inter-wire separation, both features confirmed by experimental observations. A crucial difference between the two theoretical models emerges in the temperature dependence of the drag effect. Whereas the FL theory predicts a linear temperature dependence, the LL theory promises a rich and varied dependence on temperature depending on the relative magnitudes of the energy and length scales of the systems. At higher temperatures, the drag should show a power-law dependence on temperature, R_D \~ T^x, experimentally confirmed in a narrow temperature range, where x is determined by the Luttinger liquid parameters. The spin degree of freedom plays an important role in the LL theory in predicting the features of the drag effect and is crucial for the interpretation of experimental results.Comment: 25 pages, 14 figures, to appear in Semiconductor Science and Technolog

Continuous-flow electrocoagulation (EC) process for iron removal from water: Experimental, statistical and economic study

The process of Electrocoagulation (EC), the in-situ production of coagulants by passing an electric current through sacrificial electrodes, is free of chemical additives and cost-effective. This makes it the most widely used water and wastewater treatment method. However, the literature highlights some significant drawbacks of this method including EC unit design limitations. This research therefore aimed to develop a new EC unit design using drilled plates (electrodes) to mix the solution being treated without using external mixers, this minimising power consumption. The performance of the new EC unit was validated by applying it to remove iron from water taking into account the effects of applied current density (ACD), the pH of the water (PoW), iron concentration (IC) and treatment time (TT). The effects of these parameters were optimised using the Box-Behnken model. Synthetic water samples containing different concentrations of iron (10-30 mg/l), were treated in a continuous flow, using the new EC reactor at different ACD (1.5–4.5 mA/cm2), PoW (4–10) and TT (10–50 min). The results revealed that the removal of 99.9% of iron was achieved by keeping PoW, ACD, IC and TT at 7, 3 mA/cm2, 10 mg/l and 50 min, respectively. The effects of ACD, POW, IC and TT on iron removal could be successfully simulated with R2 = 0.9788. The cost of removing iron using the proposed EC unit was 0.623 £/m3

Synthesis, Modification and Optical Characterization of Co-Cr Layered Double Hydroxide

 Cobalt and chromium based layered double hydroxides (LDHs) have been successfully synthesized by the co-precipitation method at a constant pH of 10. The intercalation of stearic acid (C18H36O2) into CoCr-LDH and preparation of their polymer nanocomposites using two different methods were studied in the paper. The obtained samples were characterized before and after modification by X-ray diffractometry (XRD) and Ultraviolet visible (UV-Vis) spectroscopy. It has been shown that different reaction temperature profoundly affects the band-gaps of inorganic and composite structures.Three optical band gap values (Eg1, Eg2 and Eg3) for the samples obtained before and after modification. Two optical band gap values were estimated in polymer/LDH nanocomposites. The high-value band gaps for CoCr-LDH(100°C)- NBR and CoCr-LDH(100°C)-SA- NBR were determined to be 5.9 eV and 5.7 eV, respectively. The low-value band gaps for CoCr-LDH(100°C)-NBR and CoCr-LDH(100°C)-SA- NBR were determined to be 4.1 eV and 3.25 eV, respectively

Caspase Inhibition with XIAP as an Adjunct to AAV Vector Gene-Replacement Therapy: Improving Efficacy and Prolonging the Treatment Window

AAV-mediated gene therapy in the rd10 mouse, with retinal degeneration caused by mutation in the rod cyclic guanosine monophosphate phosphodiesterase β-subunit (PDEβ) gene, produces significant, but transient, rescue of photoreceptor structure and function. This study evaluates the ability of AAV-mediated delivery of X-linked inhibitor of apoptosis (XIAP) to enhance and prolong the efficacy of PDEβ gene-replacement therapy.Rd10 mice were bred and housed in darkness. Two groups of animals were generated: Group 1 received sub-retinal AAV5-XIAP or AAV5-GFP at postnatal age (P) 4 or 21 days; Group 2 received sub-retinal AAV5-XIAP plus AAV5- PDEβ, AAV5-GFP plus AAV5- PDEβ, or AAV- PDEβ alone at age P4 or P21. Animals were maintained for an additional 4 weeks in darkness before being moved to a cyclic-light environment. A subset of animals from Group 1 received a second sub-retinal injection of AAV8-733-PDEβ two weeks after being moved to the light. Histology, immunohistochemistry, Western blots, and electroretinograms were performed at different times after moving to the light.Injection of AAV5-XIAP alone at P4 and 21 resulted in significant slowing of light-induced retinal degeneration, as measured by outer nuclear thickness and cell counts, but did not result in improved outer segment structure and rhodopsin localization. In contrast, co-injection of AAV5-XIAP and AAV5-PDEβ resulted in increased levels of rescue and decreased rates of retinal degeneration compared to treatment with AAV5-PDEβ alone. Mice treated with AAV5-XIAP at P4, but not P21, remained responsive to subsequent rescue by AAV8-733-PDEβ when injected two weeks after moving to a light-cycling environment.Adjunctive treatment with the anti-apoptotic gene XIAP confers additive protective effect to gene-replacement therapy with AAV5-PDEβ in the rd10 mouse. In addition, AAV5-XIAP, when given early, can increase the age at which gene-replacement therapy remains effective, thus effectively prolonging the window of opportunity for therapeutic intervention

Effective mass and peculiarity of optical properties of Cadmium Sulfide nanoparticles

X-ray diffraction data, electron microscope and optical properties of cadmium sulfide nanoparticles were analyzed. It is shown that the value of the reduced effective mass of charge carriers in nanoparticles differs from bulk crystals. Changes of effective mass and "red shift" in values of band gap are explained by the occurrence of additional electronic potential in nanoparticles