Experimental evidence for vibrational resonance and enhanced signal transmission in Chua's circuit

We consider a single Chua's circuit and a system of a unidirectionally coupled n-Chua's circuits driven by a biharmonic signal with two widely different frequencies \omega and \Omega, where \Omega >> \omega. We show experimental evidence for vibrational resonance in the single Chua's circuit and undamped signal propagation of a low-frequency signal in the system of n-coupled Chua's circuits where only the first circuit is driven by the biharmonic signal. In the single circuit, we illustrate the mechanism of vibrational resonance and the influence of the biharmonic signal parameters on the resonance. In the n(= 75)-coupled Chua's circuits enhanced propagation of low-frequency signal is found to occur for a wide range of values of the amplitude of the high-frequency input signal and coupling parameter. The response amplitude of the ith circuit increases with i and attains a saturation. Moreover, the unidirectional coupling is found to act as a low-pass filter.Comment: 15 pages, 12 figures, Accepted for Publication in International Journal of Bifurcation and Chao

Structural determinants for NF-Y/DNA interaction at the CCAAT box

The recently determined crystal structures of the sequence-specific transcription factor NF-Y have illuminated the structural mechanism underlying transcription at the CCAAT box. NF-Y is a trimeric protein complex composed by the NF-YA, NF-YB, and NF-YC subunits. NF-YB and NF-YC contain a histone-like domain and assemble on a head-to-tail fashion to form a dimer, which provides the structural scaffold for the DNA sugar-phosphate backbone binding (mimicking the nucleosome H2A/H2B\ue2\u80\u93DNA assembly) and for the interaction with NF-YA. The NF-YA subunit hosts two structurally extended \uce\ub1-helices; one is involved in NF-YB/NF-YC binding and the other inserts deeply into the DNA minor groove, providing exquisite sequence-specificity for recognition and binding of the CCAAT box. The analysis of these structural data is expected to serve as a powerful guide for future experiments aimed at understanding the role of post-translational modification at NF-Y regulation sites and to unravel the three-dimensional architecture of higher order complexes formed between NF-Y and other transcription factors that act synergistically for transcription activation. Moreover, these structures represent an excellent starting point to challenge the formation of a stable hybrid nucleosome between NF-Y and core histone proteins, and to rationalize the fine molecular details associated with the wide combinatorial association of plant NF-Y subunits

Lesiones de partes blandas por fricción

La lesión por fricción es una lesión de partes blandas que dentro de su rareza se encuentra más frecuentemente en el contexto de los accidentes de tráfico. Las fuerzas tangenciales se transmiten des del asfalto, ruedas de los vehículos a tejido celular subcutáneo conduciendo a un gran deslizamiento del mismo sobre la fascia muscular. El movimiento anormal provoca la rotura de vasos linfáticos y vasculares conduciendo una colección serohemática. Las situaciones más frecuentemente encontrada son aquellas las cuales contienen masas musculares grandes. Normalmente es una lesión de larga evolución e infradiagnosticada en sus estados iniciales. Se presenta como una tumoración fría, dolorosa e incapacitante con piel adyacente intacta o con petequías. Se diagnostica con exploración física y pruebas complementarias, como ecografía. El tratamiento teniendo en cuenta diferentes ítems puede consistir en medida conservadoras o llegar a procedimientos quirúrgicos. En la literatura no se pone de manifiesto variabilidad en los resultados de diferentes procedimientos terapéuticos.Injury by friction is an injury of soft parts that although not frequent it is not unusual in the context of the traffic accidents. The tangential forces are transmitted from the asphalt and the wheels of the vehicles to the cellular subcutaneous fabric, producing a big sliding on the muscular fascia. The abnormal movement breaks the lymphatic and vascular glasses leading to a serohematic collection. The most usual situations are that ones which contain muscular big masses. Normally it is an injury of long evolution and infradiagnosticated in its initial conditions. The skin appears as a cold, painful tumor and disabling with adjacent skin intact or with petechiae. It is diagnosed by physical exploration and with additional tests, like ultrasound scan. The treatment, considering different items, can consist on conservative measures or even surgical procedures. In the literature variability is not revealed in the results of different therapeutic procedures.Peer ReviewedAward-winnin

A mechanism explaining the metamorphoses of KAM islands in nonhyperbolic chaotic scattering

In the context of nonhyperbolic chaotic scattering, it has been shown that the evolution of the KAM islands exhibits four abrupt metamorphoses that strongly affect the predictability of Hamiltonian systems. It has been suggested that these metamorphoses are related to significant changes in the structure of the KAM islands. However, previous research has not provided an explanation of the mechanisms underlying the metamorphoses. Here, we show that they occur due to the formation of a homoclinic or heteroclinic tangle that breaks the internal structure of the main KAM island. We obtain similar qualitative results in a two-dimensional Hamiltonian system and a two-dimensional area-preserving map. The equivalence of the results obtained in both systems suggests that the same four metamorphoses play an important role in conservative systems

Extracting Hα\alpha flux from photometric data in the J-PLUS survey

We present the main steps that will be taken to extract H$\alpha$ emission flux from Javalambre Photometric Local Universe Survey (J-PLUS) photometric data. For galaxies with $z\lesssim0.015$, the H$\alpha$+[NII] emission is covered by the J-PLUS narrow-band filter $F660$. We explore three different methods to extract the H$\alpha$ + [NII] flux from J-PLUS photometric data: a combination of a broad-band and a narrow-band filter ($r'$ and $F660$), two broad-band and a narrow-band one ($r'$, $i'$ and $F660$), and a SED-fitting based method using 8 photometric points. To test these methodologies, we simulated J-PLUS data from a sample of 7511 SDSS spectra with measured H$\alpha$ flux. Based on the same sample, we derive two empirical relations to correct the derived H$\alpha$+[NII] flux from dust extinction and [NII] contamination. We find that the only unbiased method is the SED fitting based one. The combination of two filters underestimates the measurements of the H$\alpha$ + [NII] flux by a 28%, while the three filters method by a 9%. We study the error budget of the SED-fitting based method and find that, in addition to the photometric error, our measurements have a systematic uncertainty of a 4.3%. Several sources contribute to this uncertainty: differences between our measurement procedure and the one used to derive the spectroscopic values, the use of simple stellar populations as templates, and the intrinsic errors of the spectra, which were not taken into account. Apart from that, the empirical corrections for dust extinction and [NII] contamination add an extra uncertainty of 14%. Given the J-PLUS photometric system, the best methodology to extract H$\alpha$ + [NII] flux is the SED-fitting based one. Using this method, we are able to recover reliable H$\alpha$ fluxes for thousands of nearby galaxies in a robust and homogeneous way.Comment: 11 pages, 14 figures. Minor changes to match the published versio

Assessment of the potential energy hypersurfaces in thymine within multiconfigurational theory: CASSCF vs. CASPT2

The present study provides new insights into the topography of the potential energy hypersurfaces (PEHs) of the thymine nucleobase in order to rationalize its main ultrafast photochemical decay paths by employing two methodologies based on the complete active space self-consistent field (CASSCF) and the complete active space second-order perturbation theory (CASPT2) methods: (i) CASSCF optimized structures and energies corrected with the CASPT2 method at the CASSCF geometries and (ii) CASPT2 optimized geometries and energies. A direct comparison between these strategies is drawn, yielding qualitatively similar results within a static framework. A number of analyses are performed to assess the accuracy of these different computational strategies under study based on a variety of numerical thresholds and optimization methods. Several basis sets and active spaces have also been calibrated to understand to what extent they can influence the resulting geometries and subsequent interpretation of the photochemical decay channels. The study shows small discrepancies between CASSCF and CASPT2 PEHs, displaying a shallow planar or twisted 1(ππ*) minimum, respectively, and thus featuring a qualitatively similar scenario for supporting the ultrafast bi-exponential deactivation registered in thymine upon UV-light exposure. A deeper knowledge of the PEHs at different levels of theory provides useful insight into its correct characterization and subsequent interpretation of the experimental observations. The discrepancies displayed by the different methods studied here are then discussed and framed within their potential consequences in on-the-fly non-adiabatic molecular dynamics simulations, where qualitatively diverse outcomes are expected