65 research outputs found

    A comparative study between wmms and tls for the stability analysis of the San Pedro church barrel vault by means of the finite element method

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    Stability of masonry constructions is highly conditioned by the geometric disposition of its elements due to its low tensile strength and great compressive mechanical properties. Under this framework, this paper attempts to evaluate the suitability of a wearable mobile mapping solution, equipped in a backpack and based on the well-known simultaneous location and mapping paradigm, for the structural diagnosis of historical constructions. To evaluate the suitability of this device, the structural analysis obtained is compared with a high precision terrestrial laser scanner, which is considered as ground truth. The Romanesque church of San Pedro (Becerril del Carpio, Spain) was selected as a study case. This construction, initially conceived in the XIIIth century, has experimented in the past a soil settlement promoting the leaning of the north wall, several plastic hinges in its barrel vault and a visible geometrical deformation. The comparison of both techniques was carried out at different levels: i) an evaluation of the time needed to obtain the point cloud of the church; ii) an accuracy assessment based on the comparison of a terrestrial network using artificial spheres as checkpoints and; iii) an evaluation of the discrepancies, in terms of safety factor and collapse topology, found during the advance numerical evaluation of the barrel vault by means of the finite element method. This comparison places this wearable mobile mapping solution as an interesting tool for the creation of advanced numerical simulations to evaluate the structural stability of historical constructionsJunta de Castilla y León | Ref. SA075P17FEDER | Ref. SOE1/P5/P025

    Lacasa de alto potencial redox funcional en sangre mediante evolución dirigida método de obtención y sus aplicaciones

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    La presente invención describe una lacasa de alto potencial redox obtenida mediante evolución molecular dirigida que es activa en condiciones electrofisiológicas, que resiste elevadas concentraciones de haluros, que tiene una actividad significativa a pHs neutros/alcalinos y que es activa en sangre y plasma humano. La presente invención se refiere a la secuencia aminoacídica de dicha lacasa, a la secuencia nucleotídica que codifica para dicha lacasa y células que permiten su obtención. La lacasa de la invención presenta aplicaciones en diversos sectores: nano-biotecnología, biomedicina, procesos de biorremediación, industria papelera y química fina.Peer reviewedConsejop Superior de Investigaciones CientíficasA1 Solicitud de patente con informe sobre el estado de la técnic

    Lacasa de alto potencial redox funcional en sangre mediante evolución dirigida método de obtención y sus aplicaciones

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    La presente invención describe una lacasa de alto potencial redox obtenida mediante evolución molecular dirigida que es activa en condiciones electrofisiológicas, que resiste elevadas concentraciones de haluros, que tiene una actividad significativa a pHs neutros/alcalinos y que es activa en sangre y plasma humano. La presente invención se refiere a la secuencia aminoacídica de dicha lacasa, a la secuencia nucleotídica que codifica para dicha lacasa y células que permiten su obtención. La lacasa de la invención presenta aplicaciones en diversos sectores: nano-biotecnología, biomedicina, procesos de biorremediación, industria papelera y química fina.Peer reviewedConsejop Superior de Investigaciones CientíficasB1 Patente sin examen previ

    VETTONIA PROJECT: A VIRTUAL ENVIRONMENT FOR THE EDUCATIONAL DISSEMINATION OF THE IRON AGE

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    The VETTONIA project aims to disseminate the rich heritage from the Iron Age of the western Iberian Peninsula and the archaeological investigations carried out on this topic in recent years. The project utilizes new technologies such as virtual tours, 3D models, and impressions to create interactive and stimulating ways to access the results of the most recent archaeological research. Using these resources, lectures and seminars are being given in various forums with diverse types of audiences to present the virtual tours and the rest of the dissemination initiatives. In addition, the project presents its different initiatives during the annual archaeological interventions developed in the oppidum of Ulaca (Solosancho, Ávila, Spain), with good reception by the attending public. The VETTONIA project represents a pioneering dissemination experience that takes advantage of the educational opportunities offered by new technologies. In the future, tools such as virtual tours to archaeological sites may prove essential in classroom teaching at different levels and could promote sustainable tourism in fragile natural environments such as those that constitute the major settlements of the Late Iron Age (ca. 400–50 BC)

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

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    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Earth as a Tool for Astrobiology—A European Perspective

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    Lacasa de alto potencial redox funcional en sangre mediante evolución dirigida método de obtención y sus aplicaciones

    Get PDF
    La presente invención describe una lacasa de alto potencial redox obtenida mediante evolución molecular dirigida que es activa en condiciones electrofisiológicas, que resiste elevadas concentraciones de haluros, que tiene una actividad significativa a pHs neutros/alcalinos y que es activa en sangre y plasma humano. La presente invención se refiere a la secuencia aminoacídica de dicha lacasa, a la secuencia nucleotídica que codifica para dicha lacasa y células que permiten su obtención. La lacasa de la invención presenta aplicaciones en diversos sectores: nano-biotecnología, biomedicina, procesos de biorremediación, industria papelera y química fina.Peer reviewedConsejop Superior de Investigaciones CientíficasA1 Solicitud de patente con informe sobre el estado de la técnic

    Lacasa de alto potencial redox funcional en sangre mediante evolución dirigida método de obtención y sus aplicaciones

    Get PDF
    La presente invención describe una lacasa de alto potencial redox obtenida mediante evolución molecular dirigida que es activa en condiciones electrofisiológicas, que resiste elevadas concentraciones de haluros, que tiene una actividad significativa a pHs neutros/alcalinos y que es activa en sangre y plasma humano. La presente invención se refiere a la secuencia aminoacídica de dicha lacasa, a la secuencia nucleotídica que codifica para dicha lacasa y células que permiten su obtención. La lacasa de la invención presenta aplicaciones en diversos sectores: nano-biotecnología, biomedicina, procesos de biorremediación, industria papelera y química fina.Peer reviewedConsejop Superior de Investigaciones CientíficasB1 Patente sin examen previ

    Bioelectrochemical Oxidation of Water

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    Trabajo presentado en la 65th Annual Meeting of the International Society of Electrochemistry (ISE), celebrada en Lausanne del 31 de agosto al 5 de septiembre de 2017.The electrolysis of water provides a link between electrical energy and hydrogen, a high energy density fuel and a versatile energy carrier, but the process is very expensive. Indeed, the main challenge is to reduce energy consumption for large-scale applications using efficient renewable catalysts, which can be produced at low cost. Inspired by the water oxidation process catalyzed by inorganic Cu-complexes, we present the multicopper oxidase laccase as the first ever enzyme reported able to catalyze electrooxidation of H2O to molecular oxygen. Native and laboratory evolved laccases immobilized onto low-density graphite electrodes serve as bioelectrocatalytic systems with low overpotential and a high O2 evolution ratio against H2O2 production during H2O electrolysis. Our results open a new research ground on H2O splitting as they allow overcoming serious practical limitations associated with artificial electrocatalysts used for O2 evolution nowadays.N
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