572 research outputs found
Pro-p groups with few normal subgroups
Motivated by the study of pro-p groups With finite coclass, we consider the class of pro-p groups with few normal subgroups. This is not a well defined class and we offer several different definitions and study the connections between them. Furthermore, we propose a definition of periodicity for pro-p groups, thus, providing a general framework for some periodic patterns that have already been observed in the existing literature. We then focus oil examples and show that strikingly all the interesting examples not only have few normal Subgroups, but in addition have periodicity in the lattice of normal subgroups. (C) 2008 Elsevier Inc. All rights reserved
Time-sensitive autonomous architectures
Autonomous and software-defined vehicles (ASDVs) feature highly complex systems, coupling safety-critical and non-critical components such as infotainment. These systems require the highest connectivity, both inside the vehicle and with the outside world. An effective solution for network communication lies in Time-Sensitive Networking (TSN) which enables high-bandwidth and low-latency communications in a mixed-criticality environment. In this work, we present Time-Sensitive Autonomous Architectures (TSAA) to enable TSN in ASDVs. The software architecture is based on a hypervisor providing strong isolation and virtual access to TSN for virtual machines (VMs). TSAA latest iteration includes an autonomous car controlled by two Xilinx accelerators and a multiport TSN switch. We discuss the engineering challenges and the performance evaluation of the project demonstrator. In addition, we propose a Proof-of-Concept design of virtualized TSN to enable multiple VMs executing on a single board taking advantage of the inherent guarantees offered by TSN
Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity
To the Editor,
So far, little attention has been paid to the link between immunosenescence and the dramatic mortality rate of coronavirus disease 2019 (COVID-19) in older age groups. Indeed, the number of cases of COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is very low among children and teenagers, in contrast to the increased frequency in adults and the elderly, who are also more at risk of developing very serious symptoms and death (Guan et al. 2020; Wu and McGoogan 2020). As shown in Fig. 1, a similar epidemiological profile was observed during previous coronavirus (severe acute respiratory syndrome coronavirus 1, SARS-CoV-1, and Middle east respiratory syndrome coronavirus, MERS-CoV) outbreaks (Jia et al. 2009; Salamatbakhsh et al. 2019). Notably, the same trend was also noted during West Nile virus and, with some exceptions in very young children, Ebolavirus outbreaks (Bower et al. 2016; Hayes et al. 2005). Likely this phenomenon is multifactorial. For instance, in elderly individuals with severe COVID-19, associated comorbidities are much more prevalent (Guan et al. 2020). In addition, the progressive accumulation of senescent cells during life may play a role in the vulnerability of old people to COVID-19, resulting in reduced functionality of the organs, such as the lungs, and facilitating conditions for the development of fibrosis. Moreover, senescent cells can generate a pro-inflammatory environment, referred to as SASP (for senescence-associated secretory phenotype), which includes many inflammatory cytokines (e.g., interleukin-6) and contributes to the basal hyperinflammatory status characteristic of the old person. This hyperinflammatory status might influence the expression of ACE2, CD147, cyclophilins, CD26, and other CoV-associated molecules in human tissues, thus favoring viral entry (Radzikowska et al. 2020). It likely also constitutes an already unbalanced pro-inflammatory background, on which the development of an exacerbated inflammatory response and acute respiratory distress syndrome may be facilitated upon SARS-CoV-2 infection
The usefulness of Moynihan questionnaire in the evaluation of knowledge on healthy diet of patients undergoing cardiology rehabilitation
BACKGROUND: The aim of study was to test the usefulness of Moynihan questionnaire in the evaluation of knowledge on healthy diet of patients undergoing cardiology rehabilitation. METHODS: We enrolled 51 patients (pts): 41 men and 10 women, mean age 67.97 +/-11.2 years. The case study included: 21 pts that underwent coronary bypass surgery, 16 pts replaced plastic tube, 14 pts had surgery for the other reasons. All pts underwent nutritional investigation by a dietitian. Anthropometric and biochemical parameters were detected and, by the end, the Moynihan questionnaire was administrated. Pts underwent nutritional coaching, and questionnaire and dietary assessment were rechecked after 3 months. RESULTS: At baseline, the mean Questionnaire score was 22.4 +/- 3.2 points, decreased to 20.6 +/-3.1 points after 3 months (p<0.05). A detailed analysis of the questions showed that the major informations gaps were related to consumption of fruits and vegetables, consumption of fat and salt. In addition pts have acquired more general knowledge about food composition. CONCLUSIONS: The Moynihan questionnaire is an useful instrument of evaluation of dietary knowledge even in selected patients population. In the present study involving patients after cardiac surgery the main difficulties were related to high age of pts, the low cultural level and, mainly, to the post-surgery stress. However, an increase of correct answers as well as an increased knowledge about food composition were detected after educational intervention performed by the dietitian
Silagem de soja no enriquecimento de dietas compostas por silagem de ponta de cana-de-açúcar. 1 - Consumo de nutrientes.
Conduziu-se o estudo com o objetivo de avaliar o desempenho de ovinos alimentados com dietas compostas por silagem da ponta de cana-de-açúcar enriquecida com silagem de soja. Foram utilizados 24 cordeiros da raça Morada Nova com idade média de 75 dias e peso vivo médio de 16,98 kg ± 2,62 kg. Avaliaram-se as seguintes dietas: T1= 20% de silagem da ponta de cana + 80% de concentrado; T2= 20% de silagem da ponta de cana + 30% de silagem de soja + 50% de concentrado; T3= 20% de silagem da ponta de cana + 60% de silagem de soja + 20% de concentrado. O delineamento experimental foi o de blocos completos casualizados, com oito repetições. Foram avaliados os consumos de matéria seca, proteína bruta, nitrogênio contido na fibra em detergente neutro (nFDN) e na fibra em detergente ácido (nFDA). Dietas compostas por silagem de ponta de cana-de-açúcar enriquecida com silagem de soja + concentrado proporcionam maior consumo de nutrientes. A utilização de silagem de soja para enriquecer o teor protéico de dietas compostas por silagem de ponta de cana-de-açúcar fica na dependência do custo para aquisição de concentrado protéico ou produção de proteína na propriedade por meio da ensilagem da planta de soja
Influence of steps on the tilting and adsorption dynamics of ordered Pn films on vicinal Ag(111) surfaces
Here we present a structural study of pentacene (Pn) thin films on vicinal
Ag(111) surfaces by He atom diffraction measurements and density functional
theory (DFT) calculations supplemented with van der Waals (vdW) interactions.
Our He atom diffraction results suggest initial adsorption at the step edges
evidenced by initial slow specular reflection intensity decay rate as a
function of Pn deposition time. In parallel with the experimental findings, our
DFT+vdW calculations predict the step edges as the most stable adsorption site
on the surface. An isolated molecule adsorbs as tilted on the step edge with a
binding energy of 1.4 eV. In addition, a complete monolayer (ML) with
pentacenes flat on the terraces and tilted only at the step edges is found to
be more stable than one with all lying flat or tilted molecules, which in turn
influences multilayers. Hence our results suggest that step edges can trap Pn
molecules and act as nucleation sites for the growth of ordered thin films with
a crystal structure similar to that of bulk Pn.Comment: 4 pages, 4 figures, 1 tabl
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