Respuesta fisiológica al estrés agudo en conejos alimentados con dietas enriquecidas con ácidos grasos poliinsaturados n-3

A total of 700 kits were randomly distributed in flatdeck group cages avoiding litter effect. They were fed 2 isofibrous, isoenergetic and isoproteic diets formulated with 2 different sources of fat: mixed fat (control group, C, n=350) and a supplement of salmon oil rich in polyunsaturated fatty acids (PUFAs) n-3 (PUFA group, P, n=350)

Predicting workaholism in Spain: a discrete mathematical model

At the present time one of the most 'desirable' behavioural addictions that any person could develop is workaholism, a negative psychological state characterized by working excessively and compulsively. In our society, the successful person is one who spends all of their time working. Moreover, a common pattern of company management consists of stressing and putting pressure on employees to achieve the maximum profit. This trend has increased with the economic crisis in Spain and over the world. As a consequence, the terms hard working and workaholism are easily confounded, but their effects on the companies are highly different in terms of productivity. This paper proposes a discrete mathematical model to forecast the development of workaholism in Spain in the next years. A questionnaire is used in order to measure and classify our sample in subpopulations by their level of addiction. Then, different economic scenarios are simulated. Finally, economic and social consequences of this addiction are studied and public health recommendations are suggested.De La Poza, E.; Líbano, MD.; García, I.; Jódar Sánchez, LA.; Merello Giménez, P. (2014). Predicting workaholism in Spain: a discrete mathematical model. International Journal of Computer Mathematics. 91(2):233-240. https://doi.org/10.1080/00207160.2013.783205S233240912Schou Andreassen, C., Ursin, H., & Eriksen, H. R. (2007). The relationship between strong motivation to work, «workaholism», and health. Psychology & Health, 22(5), 615-629. doi:10.1080/14768320600941814Bowling, N. A., Beehr, T. A., & Swader, W. M. (2005). Giving and receiving social support at work: The roles of personality and reciprocity. Journal of Vocational Behavior, 67(3), 476-489. doi:10.1016/j.jvb.2004.08.004Burke, R. J., & Koksal, H. (2002). Workaholism among a Sample of Turkish Managers and Professionals: An Exploratory Study. Psychological Reports, 91(1), 60-68. doi:10.2466/pr0.2002.91.1.60Burke, R. J., Oberklaid, F., & Burgess, Z. (2004). Workaholism among Australian women psychologists: antecedents and consequences. Women in Management Review, 19(5), 252-259. doi:10.1108/09649420410545971De la Poza, E., Guadalajara, N., Jódar, L., & Merello, P. (2013). Modeling Spanish anxiolytic consumption: Economic, demographic and behavioral influences. Mathematical and Computer Modelling, 57(7-8), 1619-1624. doi:10.1016/j.mcm.2011.10.020Duato, R., & Jódar, L. (2013). Mathematical modeling of the spread of divorce in Spain. Mathematical and Computer Modelling, 57(7-8), 1732-1737. doi:10.1016/j.mcm.2011.11.020Fry, L. W., & Cohen, M. P. (2008). Spiritual Leadership as a Paradigm for Organizational Transformation and Recovery from Extended Work Hours Cultures. Journal of Business Ethics, 84(S2), 265-278. doi:10.1007/s10551-008-9695-2García, I., Jódar, L., Merello, P., & Santonja, F.-J. (2011). A discrete mathematical model for addictive buying: Predicting the affected population evolution. Mathematical and Computer Modelling, 54(7-8), 1634-1637. doi:10.1016/j.mcm.2010.12.012Gustafsson, P. E., Janlert, U., Virtanen, P., & Hammarström, A. (2012). The association between long-term accumulation of temporary employment, the cortisol awakening response and circadian cortisol levels. Psychoneuroendocrinology, 37(6), 789-800. doi:10.1016/j.psyneuen.2011.09.011Hochschild, A. (1997). The Time Bind. WorkingUSA, 1(2), 21-29. doi:10.1111/j.1743-4580.1997.tb00019.xNelder, J. A., & Mead, R. (1965). A Simplex Method for Function Minimization. The Computer Journal, 7(4), 308-313. doi:10.1093/comjnl/7.4.308Ng, T. W. H., Sorensen, K. L., & Feldman, D. C. (2006). Dimensions, antecedents, and consequences of workaholism: a conceptual integration and extension. Journal of Organizational Behavior, 28(1), 111-136. doi:10.1002/job.424W.E. Oates,Confessions of a Workaholic: The Facts about Work Addiction, World Publishing Company, New York, 1971.Raafat, R. M., Chater, N., & Frith, C. (2009). Herding in humans. Trends in Cognitive Sciences, 13(10), 420-428. doi:10.1016/j.tics.2009.08.002Robinson, B. E., & Post, P. (1997). Risk of Addiction to Work and Family Functioning. Psychological Reports, 81(1), 91-95. doi:10.2466/pr0.1997.81.1.91Schaufeli, W. B., & Bakker, A. B. (2004). Job demands, job resources, and their relationship with burnout and engagement: a multi-sample study. Journal of Organizational Behavior, 25(3), 293-315. doi:10.1002/job.248Schaufeli, W. B., Bakker, A. B., & Salanova, M. (2006). The Measurement of Work Engagement With a Short Questionnaire. Educational and Psychological Measurement, 66(4), 701-716. doi:10.1177/0013164405282471Schaufeli, W. B., Taris, T. W., & van Rhenen, W. (2008). Workaholism, Burnout, and Work Engagement: Three of a Kind or Three Different Kinds of Employee Well-being? Applied Psychology, 57(2), 173-203. doi:10.1111/j.1464-0597.2007.00285.xSchaufeli, W. B., Bakker, A. B., van der Heijden, F. M. M. A., & Prins, J. T. (2009). Workaholism, burnout and well-being among junior doctors: The mediating role of role conflict. Work & Stress, 23(2), 155-172. doi:10.1080/02678370902834021Shimazu, A., Schaufeli, W. B., & Taris, T. W. (2010). How Does Workaholism Affect Worker Health and Performance? The Mediating Role of Coping. International Journal of Behavioral Medicine, 17(2), 154-160. doi:10.1007/s12529-010-9077-xSonnentag, S. (2003). Recovery, work engagement, and proactive behavior: A new look at the interface between nonwork and work. Journal of Applied Psychology, 88(3), 518-528. doi:10.1037/0021-9010.88.3.518Yaniv, G. (2011). Workaholism and marital estrangement: A rational-choice perspective. Mathematical Social Sciences, 61(2), 104-108. doi:10.1016/j.mathsocsci.2010.11.00

Automated Program Analysis for Novice Programmers

[EN] This paper describes how to adapt a static code analyzer to provide feedback novice programmers and their teachers. Current analyzers have been built to give feedback to experienced programmers who work on software projects or systems. The type of feedback and the type of analysis of these tools focusses on mistakes that are relevant within that context, and help with debugging software system. When teaching novice programmers this type of advice is often not particularly useful. It would be instead more useful to use these techniques to identify problem in the understanding of students of important programming concepts. This paper first explores in what respect static analyzers support the learning and teaching of programming, and what can be implemented based on existing static analysis technology. It presents an extension of static analyzer PMD to create feedback that is more valuable to novice programmers. To answer the question if these techniques are able to find conceptual mistakes that are characteristic for novice programmers make, we ran it over a number of student projects, and compared these results with publicly available mature software projects.Blok, T.; Fehnker, A. (2017). Automated Program Analysis for Novice Programmers. En Proceedings of the 3rd International Conference on Higher Education Advances. Editorial Universitat Politècnica de València. 1138-1146. https://doi.org/10.4995/HEAD17.2017.5533OCS1138114

Mathematical Modeling of the Consumption of Low Invasive Plastic Surgery Practices: The Case of Spain

Copyright © 2013 E. De la Poza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.[EN] Plastic surgery practice grows continuously among the women in Western countries due to their body image dissatisfaction, aging anxiety, and an ideal body image propagated by the media. The consumption growth is so important that plastic surgery is becoming a normal practice among women, like any other cosmetic product, with the risk of suffering psychopathology disorders in the sense that plastic surgery could be employed as an instrument to recover personal self-esteem or even happiness. Plastic surgery practice depends on economic, demographic, and social contagion factors. In this paper, a mathematical epidemiological model to forecast female plastic surgery consumption in Spain is fully constructed. Overconsumer subpopulation is predicted and simulated. Robustness of the model versus uncertain parameters is studied throughout a sensitivity analysis.The authors would like to thank the European Union since this paper has been financed throughout the Project FP7-PEOPLE-2012-ITN Grant Agreement no. 304617 (FP7Marie Curie Action, Project Multi-ITN STRIKE-Novel Methods in Computational Finance). The authors also thank the Hadhramout University of Sciences and Technology of Yemen for financing the Ph.d. grant for M. S. S. Alkasadi.De La Poza, E.; Alkasadi, MSS.; Jódar Sánchez, LA. (2013). Mathematical Modeling of the Consumption of Low Invasive Plastic Surgery Practices: The Case of Spain. Abstract and Applied Analysis. 2013:1-8. https://doi.org/10.1155/2013/169253S18201

Using Virtual Reality to promote pre-service teachers’ classroom management skills and teacher resilience: A qualitative evaluation

[EN] Many novice teachers have difficulties in selecting and applying effective classroom management strategies to prevent or diminish disruptive behaviors. Negative experiences with classroom management largely determine teacher wellbeing and early attrition. Therefore, more in-training opportunities are needed to prepare prospective teachers to manage complex classroom practices effectively. A Virtual Reality-environment seems promising in developing classroom management skills and promoting teacher resilience; however, its potential is influenced by students’ perceptions towards this technology. This study describes four pre-service teachers’ and six school-based teacher educators’ experiences with and perceptions towards the use of a Virtual Reality learning environment to train classroom management skills and promote teacher resilience. Responses of semi-structured interviews reflect five themes: software- and equipment-related issues; feedback cues; realism and authenticity; instructor proficiency; and added value for teacher training. Results show that, for most themes, pre-service teachers and school-based teacher educators raised similar remarks and/or suggestions for improvement; however, they differed in their perceptions towards the added value of Virtual Reality to teacher training curricula. Our study highlights teachers’ needs for highly authentic and realistic simulations aligned with real-life classrooms and presents recommendations to augment the immersive experience needed for teachers to develop effective CMS and become more resilient.Mouw, J.; Fokkens-Bruinsma, M.; Verheij, G. (2020). Using Virtual Reality to promote pre-service teachers’ classroom management skills and teacher resilience: A qualitative evaluation. En 6th International Conference on Higher Education Advances (HEAd'20). Editorial Universitat Politècnica de València. (30-05-2020):325-332. https://doi.org/10.4995/HEAd20.2020.11049OCS32533230-05-202

Facebook usage by students in higher education

[EN] In this paper I measure first year student Facebook usage as part of a broader PhD study into the influence of social media usage on the success of students in higher education. A total of 906 students were asked to complete 3 surveys on Facebook usage with their peers, for two consecutive years (2011-2012 and 2012-2013). The different purposes for Facebook usage, in addition to whether or not students used (self-created) Facebook-groups, were measured and the relationship between the use of pages compared to the purpose of Facebook usage. This resulted in significant correlations between the purpose of Facebook usage and the use of different pages, as well as correlations between the purpose and use of different pages. This study hereby explores the variation in student Facebook usage and provides valuable insight into the potential value of Facebook for students in an educational setting, without the interference of teachers. It is also the next logical step in revising existing integration and engagement theories that predict student successin higher education in contemporary society.Wesseling, N. (2015). Facebook usage by students in higher education. En 1ST INTERNATIONAL CONFERENCE ON HIGHER EDUCATION ADVANCES (HEAD' 15). Editorial Universitat Politècnica de València. 593-599. https://doi.org/10.4995/HEAd15.2015.395OCS59359

A proposal to analyse the progress and difficulties of Higher Education teacher training

[EN] This article presents an ongoing research study whose purpose is to describe and analyse the progress and difficulties participants face in a university teacher training programme offered by the University of Seville. The training programme and the different parts of the research strategy are described.This study is part of a larger research project entitled Pedagogical training of university teachers. Progress and obstacles in a training programme focusing on improving teaching practice (EDU2016- 75604-P), financed by the Ministry of Economy and Competitiveness 2016 R&D fund.http://ocs.editorial.upv.es/index.php/HEAD/HEAD18Hamed Al-Lal, S.; Pineda Alfonso, JA.; Pérez Rodríguez, N.; Navarro-Medina, E.; Duarte Piña, O. (2018). A proposal to analyse the progress and difficulties of Higher Education teacher training. Editorial Universitat Politècnica de València. 979-987. https://doi.org/10.4995/HEAD18.2018.8130OCS97998

Modelling the propagation of adult male muscle dysmorphia in Spain: economic, emotional and social drivers

This is an author's accepted manuscript of an article published in: “Applied Economics"; Volume 47, Issue 12, 2015; copyright Taylor & Francis; available online at: http://dx.doi.org/10.1080/00036846.2013.870657Males aged over 40 do more gym practice to improve their body image as a way of reinforcing their personal self-esteem and sexual appeal. Cases when self-image becomes an obsession may result in a body dysmorphic disorder named ‘muscle dysmorphia’ (MD). The combination of psychological, environmental and biological drivers determines the appearance and development of this disorder. In this article, we developed a discrete population mathematical model to forecast the rate of prevalence of males who are noncompetitive bodybuilders at risk of suffering MD in Spain in forthcoming years. Economic, emotional, sociological and psychological motivations were taken into account to quantify the dynamic behaviour of Spanish noncompetitive bodybuilders. The impact of the unemployment is reflected in the construction of two coefficients, αu and α21, which explain subpopulation transits due to the economy. Sociological influences, such as human herding and social propagation, were also considered. Our results predict an increase in Spanish noncompetitive bodybuilders suffering MD from 1% in 2011 to around 11% in 2015. Our model can be applied to any other western country where data are available and to another study period when the hypotheses are applicable.De La Poza, E.; Jódar Sánchez, LA.; Alkasadi, M. (2015). Modelling the propagation of adult male muscle dysmorphia in Spain: economic, emotional and social drivers. Applied Economics. 47(12):1159-1169. https://doi.org/10.1080/00036846.2013.870657S115911694712Blashfield, R. K., Sprock, J., & Fuller, A. K. (1990). Suggested guidelines for including or excluding categories in the DSM-IV. Comprehensive Psychiatry, 31(1), 15-19. doi:10.1016/0010-440x(90)90049-xBoyda, D., & Shevlin, M. (2011). Childhood victimisation as a predictor of muscle dysmorphia in adult male bodybuilders. The Irish Journal of Psychology, 32(3-4), 105-115. doi:10.1080/03033910.2011.616289Brown, J., & Graham, D. (2008). Body Satisfaction in Gym-active Males: An Exploration of Sexuality, Gender, and Narcissism. Sex Roles, 59(1-2), 94-106. doi:10.1007/s11199-008-9416-4Brown, J. T. (2005). Anabolic Steroids: What Should the Emergency Physician Know? Emergency Medicine Clinics of North America, 23(3), 815-826. doi:10.1016/j.emc.2005.03.012Chaney, M. P. (2008). Muscle Dysmorphia, Self-esteem, and Loneliness among Gay and Bisexual Men. International Journal of Men’s Health, 7(2), 157-170. doi:10.3149/jmh.0702.157Choi, P. Y. L. (2002). Muscle dysmorphia: a new syndrome in weightlifters * Commentary. British Journal of Sports Medicine, 36(5), 375-376. doi:10.1136/bjsm.36.5.375Christakis, N. A., & Fowler, J. H. (2007). The Spread of Obesity in a Large Social Network over 32 Years. New England Journal of Medicine, 357(4), 370-379. doi:10.1056/nejmsa066082Cohane, G. H., & Pope, H. G. (2001). Body image in boys: A review of the literature. International Journal of Eating Disorders, 29(4), 373-379. doi:10.1002/eat.1033Duato, R., & Jódar, L. (2013). Mathematical modeling of the spread of divorce in Spain. Mathematical and Computer Modelling, 57(7-8), 1732-1737. doi:10.1016/j.mcm.2011.11.020Eide, E. R., & Ronan, N. (2001). Is participation in high school athletics an investment or a consumption good? Economics of Education Review, 20(5), 431-442. doi:10.1016/s0272-7757(00)00033-9Farrell, L., & Shields, M. A. (2002). Investigating the economic and demographic determinants of sporting participation in England. Journal of the Royal Statistical Society: Series A (Statistics in Society), 165(2), 335-348. doi:10.1111/1467-985x.00626French, S. A., Story, M., Downes, B., Resnick, M. D., & Blum, R. W. (1995). Frequent dieting among adolescents: psychosocial and health behavior correlates. American Journal of Public Health, 85(5), 695-701. doi:10.2105/ajph.85.5.695García, I., Jódar, L., Merello, P., & Santonja, F.-J. (2011). A discrete mathematical model for addictive buying: Predicting the affected population evolution. Mathematical and Computer Modelling, 54(7-8), 1634-1637. doi:10.1016/j.mcm.2010.12.012González-Martí, I., Bustos, J. G. F., Jordán, O. R. C., & Mayville, S. B. (2012). Validation of a Spanish version of the Muscle Appearance Satisfaction Scale: Escala de Satisfacción Muscular. Body Image, 9(4), 517-523. doi:10.1016/j.bodyim.2012.05.002Greenberg, J. L., Markowitz, S., Petronko, M. R., Taylor, C. E., Wilhelm, S., & Wilson, G. T. (2010). Cognitive-Behavioral Therapy for Adolescent Body Dysmorphic Disorder. Cognitive and Behavioral Practice, 17(3), 248-258. doi:10.1016/j.cbpra.2010.02.002Hildebrandt, T., Schlundt, D., Langenbucher, J., & Chung, T. (2006). Presence of muscle dysmorphia symptomology among male weightlifters. Comprehensive Psychiatry, 47(2), 127-135. doi:10.1016/j.comppsych.2005.06.001Hitzeroth, V., Wessels, C., Zungu-Dirwayi, N., Oosthuizen, P., & Stein, D. J. (2001). Muscle dysmorphia: A South African sample. Psychiatry and Clinical Neurosciences, 55(5), 521-523. doi:10.1046/j.1440-1819.2001.00899.xHONEKOPP, J., RUDOLPH, U., BEIER, L., LIEBERT, A., & MULLER, C. (2007). Physical attractiveness of face and body as indicators of physical fitness in men. Evolution and Human Behavior, 28(2), 106-111. doi:10.1016/j.evolhumbehav.2006.09.001Humphreys, B. R., & Ruseski, J. E. (2011). An Economic Analysis of Participation and Time Spent in Physical Activity. The B.E. Journal of Economic Analysis & Policy, 11(1). doi:10.2202/1935-1682.2522Kanayama, G. (2006). Body Image and Attitudes Toward Male Roles in Anabolic-Androgenic Steroid Users. American Journal of Psychiatry, 163(4), 697. doi:10.1176/appi.ajp.163.4.697Keery, H., van den Berg, P., & Thompson, J. K. (2004). An evaluation of the Tripartite Influence Model of body dissatisfaction and eating disturbance with adolescent girls. Body Image, 1(3), 237-251. doi:10.1016/j.bodyim.2004.03.001Mosley, P. E. (2009). Bigorexia: bodybuilding and muscle dysmorphia. European Eating Disorders Review, 17(3), 191-198. doi:10.1002/erv.897Murray, S. B., Rieger, E., Touyz, S. W., & De la Garza García Lic, Y. (2010). Muscle dysmorphia and the DSM-V conundrum: Where does it belong? A review paper. International Journal of Eating Disorders, 43(6), 483-491. doi:10.1002/eat.20828Nieuwoudt, J. E., Zhou, S., Coutts, R. A., & Booker, R. (2012). Muscle dysmorphia: Current research and potential classification as a disorder. Psychology of Sport and Exercise, 13(5), 569-577. doi:10.1016/j.psychsport.2012.03.006Olivardia, R. (2001). Mirror, Mirror on the Wall, Who’s the Largest of Them All? The Features and Phenomenology of Muscle Dysmorphia. Harvard Review of Psychiatry, 9(5), 254-259. doi:10.1080/hrp.9.5.254.259Olivardia, R., Pope, H. G., & Hudson, J. I. (2000). Muscle Dysmorphia in Male Weightlifters: A Case-Control Study. American Journal of Psychiatry, 157(8), 1291-1296. doi:10.1176/appi.ajp.157.8.1291Phillips, K. A. (2009)Understanding Body Dysmorphic Disorder an Essential Guide, 49, Oxford University Press, New York, NY.Phillips, K. A., Wilhelm, S., Koran, L. M., Didie, E. R., Fallon, B. A., Feusner, J., & Stein, D. J. (2010). Body dysmorphic disorder: some key issues for DSM-V. Depression and Anxiety, 27(6), 573-591. doi:10.1002/da.20709Pompper, D. (2010). Masculinities, the Metrosexual, and Media Images: Across Dimensions of Age and Ethnicity. Sex Roles, 63(9-10), 682-696. doi:10.1007/s11199-010-9870-7Pope, H. G., Gruber, A. J., Choi, P., Olivardia, R., & Phillips, K. A. (1997). Muscle Dysmorphia: An Underrecognized Form of Body Dysmorphic Disorder. Psychosomatics, 38(6), 548-557. doi:10.1016/s0033-3182(97)71400-2Pope, H. G., Gruber, A. J., Mangweth, B., Bureau, B., deCol, C., Jouvent, R., & Hudson, J. I. (2000). Body Image Perception Among Men in Three Countries. American Journal of Psychiatry, 157(8), 1297-1301. doi:10.1176/appi.ajp.157.8.1297Kanayama, G., Brower, K. J., Wood, R. I., Hudson, J. I., & Pope, H. G. (2009). Issues for DSM-V: Clarifying the Diagnostic Criteria for Anabolic-Androgenic Steroid Dependence. American Journal of Psychiatry, 166(6), 642-645. doi:10.1176/appi.ajp.2009.08111699Pope, H. G., Katz, D. L., & Hudson, J. I. (1993). Anorexia nervosa and «reverse anorexia» among 108 male bodybuilders. Comprehensive Psychiatry, 34(6), 406-409. doi:10.1016/0010-440x(93)90066-dPopkin, B. M. (2003). The Nutrition Transition in the Developing World. Development Policy Review, 21(5-6), 581-597. doi:10.1111/j.1467-8659.2003.00225.xRaafat, R. M., Chater, N., & Frith, C. (2009). Herding in humans. Trends in Cognitive Sciences, 13(10), 420-428. doi:10.1016/j.tics.2009.08.002RICCIARDELLI, L. A., & McCABE, M. P. (2003). Sociocultural and individual influences on muscle gain and weight loss strategies among adolescent boys and girls. Psychology in the Schools, 40(2), 209-224. doi:10.1002/pits.10075Silver, M. D. (2001). Use of Ergogenic Aids by Athletes. Journal of the American Academy of Orthopaedic Surgeons, 9(1), 61-70. doi:10.5435/00124635-200101000-00007Smolak, L., Levine, M. P., & Schermer, F. (1999). Parental input and weight concerns among elementary school children. International Journal of Eating Disorders, 25(3), 263-271. doi:10.1002/(sici)1098-108x(199904)25:33.0.co;2-vVarangis, E., Lanzieri, N., Hildebrandt, T., & Feldman, M. (2012). Gay male attraction toward muscular men: Does mating context matter? Body Image, 9(2), 270-278. doi:10.1016/j.bodyim.2012.01.003Catherine Walker, D., Anderson, D. A., & Hildebrandt, T. (2009). Body checking behaviors in men. 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Exploring the impact of cumulative testing on academic performance of undergraduate students in Spain

The final publication is available at Springer via http://dx.doi.org/10.1007/s11092-014-9208-zFrequent testing provides opportunities for students to receive regular feedback and to increase their motivation. It also provides the instructor with valuable information on how course progresses, thus making it possible to solve the problems encountered before it is too late. Frequent tests with noncumulative contents have been widely analysed in the literature with inconclusive results. However, cumulative testing methods have hardly been reported in higher education courses. This paper analyses the effect of applying an assessment method based on frequent and cumulative tests on student performance. Our results show that, when applied to a microeconomics course, students who were assessed by a frequent, cumulative testing approach largely outperformed those assessed with a single final exam.Doménech I De Soria, J.; Blázquez Soriano, MD.; De La Poza, E.; Muñoz Miquel, A. (2015). Exploring the impact of cumulative testing on academic performance of undergraduate students in Spain. Educational Assessment, Evaluation and Accountability. 27(2):153-169. https://doi.org/10.1007/s11092-014-9208-zS153169272Adelman, HS, & Taylor, L. (1990). Intrinsic motivation and school misbehaviour some intervention implications. Journal of Learning Disabilities, 23, 541–550.Biggs, J, & Tang, C. (2007). Teaching for quality learning at university 3rd edn. Open University Press.Boston, C. (2002). The concept of formative assessment. Practical Assessment Research & Evaluation 8.Brown, GA, Bull, J, Pendlebury, M. (1997). Assessing Student Learning in Higher Education, 1st edn. Routledge.Cano, MD. (2011). Students’ involvement in continuous assessment methodologies: a case study for a distributed information systems course. IEEE Transactions on Education, 54, 442–451.Casem, ML (2006). Active learning is not enough. Journal of College Science Teaching, 35.Chen, J, & Lin, TF. (2008). Class attendance and exam performance a randomized experiment. The Journal of Economic Education, 39, 213–227.Chickering, AW, & Gamson, ZF. (1987). Seven principles for good practice in undergraduate education. American Association for Higher Education Bulletin, 39, 3–7.Crooks, TJ. (1988). The impact of classroom evaluation practices on students. Review of Educational Research, 58, 438–481.De Paola, M, & Scoppa, V. (2011). Frequency of examinations and student achievement in a randomized experiment. Economics of Education Review, 30, 1416–1429.Deck, W. (1998). The effects of frequency of testing on college students in a principles of marketing course, PhD thesis, Virginia Polytechnic Institute and State University. Virginia: Blacksburg.Dempster, FN. (1991). Synthesis of research on reviews and tests. Educational Leadership, 48, 71–76.Dochy, F. (2008). The Edumetric Quality of New Modes of Assessment: Some Issues and Prospects. Assessment, Learning and Judgement in Higher Education. 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BRIVA-LIFE–A multicenter retrospective study of the long-term use of brivaracetam in clinical practice

Objectives: Evaluate long-term effectiveness and tolerability of brivaracetam in clinical practice in patients with focal epilepsy. Materials and Methods: This was a multicenter retrospective study. Patients aged =16 years were started on brivaracetam from November 2016 to June 2017 and followed over 1 year. Data were obtained from medical records at 3, 6 and 12 months after treatment initiation for evaluation of safety- and seizure-related outcomes. Results: A total of 575 patients were included in analyses; most had been treated with =4 lifetime antiepileptic drugs. Target dosage was achieved by 30.6% of patients on the first day. Analysis of primary variables at 12 months revealed that mean reduction in seizure frequency was 36.0%, 39.7% of patients were =50% responders and 17.5% were seizure-free. Seizure-freedom was achieved by 37.5% of patients aged =65 years. Incidence of adverse events (AEs) and psychiatric AEs (PAEs) was 39.8% and 14.3%, respectively, and discontinuation due to these was 8.9% and 3.7%, respectively. Somnolence, irritability, and dizziness were the most frequently reported AEs. At baseline, 228 (39.7%) patients were being treated with levetiracetam; most switched to brivaracetam (dose ratio 1:10-15). Among those who switched because of PAEs (n = 53), 9 (17%) reported PAEs on brivaracetam, and 3 (5.7%) discontinued because of PAEs. Tolerability was not highly affected among patients with learning disability or psychiatric comorbidity. Conclusions: In a large population of patients with predominantly drug-resistant epilepsy, brivaracetam was effective and well-tolerated; no unexpected AEs occurred over 1 year, and the incidence of PAEs was lower compared with levetiracetam