Making the Business Case for Sustainable Design in the Department of Defense

Buildings are one of the largest consumers of natural resources, a major source of ecological pollution, and occasionally toxic to human health. Sustainable design is the common term associated with buildings which, during their construction, use, and eventual disposal, seek to minimize their negative impact on the environment and human health. The U.S. Green Building Council\u27s Leadership in Energy and Environmental Design (LEED) rating system helps to assess a building\u27s sustainability level. In the Federal Government\u27s push to set the example for the rest of the nation, nearly every Federal Agency has chosen to adopt the LEED assessment tool. Each of the Armed Services in the Department of Defense (DoD) has set ambitious LEED certification goals. Despite their stated goals and the clear environmental and health benefits of LEED, a common concern is that LEED-designed buildings are simply too costly to construct. However, many proponents profess that LEED-designed buildings shouldn\u27t cost significantly more than conventionally designed and constructed buildings and that the operational life-cycle cost savings rapidly compensate for any additional initial costs. Unfortunately, no comprehensive studies on initial construction costs have been performed in the DoD. Therefore, it continues to be the primary source of unit-level resistance to LEED and sustainable design. This research gathered historical cost data from 22 completed Federal construction projects and used statistical analysis to explore whether a business case could be made to support LEED using initial construction costs in the DoD. Results from the analysis were mixed. Hypothesis testing deemed there was no statistical difference in cost between LEED and conventionally designed facility construction. While on average LEED buildings were only 1.9% more expensive to construct than conventional facilities, the 9.2% standard deviation made it difficult to make a favorable business case. (94 refs.

HyperImage – Image-Oriented e-Science Networks

Images are an important source of scientific knowledge in many disciplines. E.g. you want to analyse satellite photographs or x-ray images of human livers or symbols of death in Dutch baroque paintings. You study the relevant images closely and compare details of one image with details of another. When you want to share your knowledge you will necessarily also communicate about image details. Using paper images, you can just mark up details of interest with a pencil. But with digital images you either have to make marks by employing an image manipulation software, which is not as widespread and easy to use as current text processing software is. Or you have to describe your findings verbally, such as "... above left is an interesting dark spot in picture No. 1 ... now compare it to picture No. 2 where a similar dark spot can be found nearly in the centre of the picture ..." and so on. Neither the employment of a complex image manipulation software package nor the time consuming and not very precise verbal description is satisfactory and appropriate for everyday use in science. Additionally, any technical solution to the lack of easy-to-use technology has to be Web-based in order to support collaborative research on images. The HyperImage project is concerned with the currently unsolved technical problem of establishing links between image details. Our goal is to develop a Web-based workspace that will enable scientists in any image-oriented discipline to create simple and precise links between images and image details, in a fashion similar to that which until now has been the privilege of text. The HyperImage editor permits scientists to mark details of pictures and create links between images and image details of any scale. It is programmed as a platform independent Java application and is open source (GNU Lesser General Public Licence). Any work in progress can be stored within the Hyper- Image system by an author or group of authors, or it can be exported as XML for further usage outside the HyperImage system. Currently we are testing our software prototype with our HyperImage partners from the faculties of Art History and Biology

Unambiguous identification of esters as oligomers in secondary organic aerosol formed from cyclohexene and cyclohexene/α-pinene ozonolysis

The build-up of oligomeric compounds during secondary organic aerosol (SOA) formation is subject of atmospheric research since several years. New particle formation and especially the SOA mass yield might be influenced significantly by oligomer formation. However, the chemical nature of observed oligomers and their formation pathways are still unclear. In this paper, the structural characterization of certain dimeric compounds (esters) formed during the ozonolysis of cyclohexene and cyclohexene/α-pinene mixtures are presented. The identification is based on the comparison of the mass spectra and the retention times (LC) of the oligomeric products with synthesized reference compounds. Cyclohexene is used here as a model compound for terpenes as globally most important SOA precursors, since it possesses a simpler structure than the biogenic alkenes and therefore offers the possibility to get access to reference compounds for certain of its oxidation products. In addition to cyclohexene, the formation of esters could also be observed in experiments with α-pinene as reactant

Photodissociation of Conformer-Selected Ubiquitin Ions Reveals Site-Specific Cis/Trans Isomerization of Proline Peptide Bonds

Ultraviolet photodissociation (UVPD) of gas-phase proteins has attracted increased attention in recent years. This growing interest is largely based on the fact that, in contrast to slow heating techniques such as collision induced dissociation (CID), the cleavage propensity after absorption of UV light is distributed over the entire protein sequence, which can lead to a very high sequence coverage as required in typical top-down proteomics applications. However, in the gas phase, proteins can adopt a multitude of distinct and sometimes coexisting conformations, and it is not clear how this three-dimensional structure affects the UVPD fragmentation behavior. Using ion mobility–UVPD–mass spectrometry in conjunction with molecular dynamics simulations, we provide the first experimental evidence that UVPD is sensitive to the higher order structure of gas-phase proteins. Distinct UVPD spectra were obtained for different extended conformations of 11+ ubiquitin ions. Assignment of the fragments showed that the majority of differences arise from cis/trans isomerization of one particular proline peptide bond. Seen from a broader perspective, these data highlight the potential of UVPD to be used for the structural analysis of proteins in the gas phas

Consistency of QTL for Dollar Spot Resistance Between Greenhouse and Field Inoculations, Multiple Locations, and Different Population Sizes in Creeping Bentgrass

Dollar spot caused by Sclerotinia homoeocarpa F. T. Bennett is the most economically important turf disease in North America. Previous work indicated differences among cultivars in their susceptibility to dollar spot (Bonos et al., 2003). Studies have indicated that dollar spot resistance might be quantitatively inherited (Bonos et al., 2003) but the number, location and effect of genomic regions conferring resistance is still not known. Therefore the objective of this research is to understand the effect of population size, inoculation assays, and field locations on QTL for dollar spot resistance in creeping bentgrass

Native like helices in a specially designed β peptide in the gas phase

In the natural peptides, helices are stabilized by hydrogen bonds that point backward along the sequence direction. Until now, there is only little evidence for the existence of analogous structures in oligomers of conformationally unrestricted β amino acids. We specifically designed the β peptide Ac-(β2hAla)6-LysH+ to form native like helical structures in the gas phase. The design follows the known properties of the peptide Ac-Ala6-LysH+ that forms a α helix in isolation. We perform ion-mobility mass-spectrometry and vibrational spectroscopy in the gas phase, combined with state-of-the-art density-functional theory simulations of these molecular systems in order to characterize their structure. We can show that the straightforward exchange of alanine residues for the homologous β amino acids generates a system that is generally capable of adopting native like helices with backward oriented H-bonds. By pushing the limits of theory and experiments, we show that one cannot assign a single preferred structure type due to the densely populated energy landscape and present an interpretation of the data that suggests an equilibrium of three helical structures

Going Beyond Promoting: Preparing Students to Creatively Solve Future Problems

While we cannot know what problems the future will bring, we can be almost certain that solving them will require creativity. In this article we describe how our course, a first-year undergraduate mathematics course, supports creative problem solving. Creative problem solving cannot be learned through a single experience, so we provide our students with a blend of experiences. We discuss how the course structure enables creative problem solving through class instruction, during class activities, during out of class assessments, and during in class assessments. We believe this course structure increases student comfort with solving open-ended and ill-defined problems similar to what they will encounter in the real world