Experimental studies on twinjet afterbody-nozzle system of combat aircraft configurations

This report highlights the progress of the work carried out in the above project including the statement of expenditure for presentation at AR&DB annual symposium-201

Three Phase Active Shunt Power Filter with Simple Control in PSIM Simulation

Generally the electrical system used by many consumer and industry usually uses passive filter and capacitor bank to compensate, harmonics and reactive power absorbed by the loads .The passive filter and capacitor bank make harmonic resonance with input impedance so that magnitude of harmonic current increased with harmonic frequency generated by nonlinear load. In this paper a simple active filter with PSIM simulation model used, the reference current generated by simple method of power synchronous detection and gate pulses generated by the use of modulated hysteresis current controller. The proposed model compensates current harmonics, and it  does power factor correction. The active filter designed in PSIM software and control of active filter is done in Simulink environment. PSIM and MATLAB software is linked by Sim coupler. The capacitor voltage is maintained constant by using PI controller. Simulation results with PSIM software shows that the designed active filter is very effective in harmonic elimination and power factor correction Keywords: : Active filter, Modulated Hysteresis current control, power synchronous detection (PSD),current harmonics, Pulse Width Modulation, , PSIM software

Ethnomedicinal Plants Survey and Documentation Related to Paliyar Community

The present study is mainly focused on the ethnomedico botany of the tribe Paliyars a dominant ethnic group inhabiting the Western Ghats (Off Shoots) of Sirumalai Hills, Dindigul district. Tamil Nadu. In the present study the focus is on survey, documentation and enumeration of the medicinal plants practiced by the tribal Paliyars, As an outcome of the present investigations 30 plants have been identified and documented. The life style of the Paliyar was also studied

A Study on Urinary Bacterial and Fungal Isolates and their Antimicrobial Susceptibility Pattern from Patients Undergoing Invasive Urological OP Diagnostic Procedures including Cystoscopy and Urodynamic Study

OBJECTIVES: To isolate and identify the bacterial and fungal causative agents for post procedure of urinary tract infection in patients undergoing cystoscopy and urodynamic (UD) evaluation in a prospective survey. To study the association of ompT virulent gene for E.coli with significant colony counts. The tolerability and acceptance of and UD studies by patients have not been thoroughly documented. It would be helpful to be able to give such information to patients before performing these procedures. METHODS: A total of 200 patients seen as outpatients for Cystoscopy and Urodynamic studies to evaluate various indications were studied. A midstream urine sample was taken before,third day and seventh after the procedures and semiquantitative culture was employed for colony counts. Detection of virulent gene ompT for E.coli by conventional PCR. Patients were given a uestionnaire that inquired about the presence of lower urinary tract symptoms after the procedures. RESULTS: Of the 200 patients analyzed (Cystoscopy100, UD studies 100), 9 patients (4.5%) developed significant bacteriuria .E.coli (40.9%) was the commonest isolated organism. ompT gene was negative for E.coli with significant colony counts. Only 2 patients (2%) with significant bacteriuria symptoms. The association between patients who had symptoms with significant growth and underlying condition after the procedure (n = 2) was significant (P<0.05). ompT gene. CONCLUSIONS: Cystoscopy and Urodynamic studies are safe, well-tolerated procedures. The antibiotics for the transieint infection of these procedures is unnecessary, unless specific indications are present

A Survey of the Ethnomedicinal Flora of the Sirumalai Hills, Dindugul District, India

The present study is mainly focused on the ethnomedico botany of the tribe Paliyars a dominant ethnic group inhabiting the Western Ghats (Off Shoots) of Sirumalai Hills, Dindigul district, Tamil Nadu. In the present study the focus is on survey, documentation and enumeration of the medicinal plants practiced by the tribal Paliyars. As an outcome of the present investigations 25 plants have been identified and documented

Nutritional assessment and bioactive potential of Sargassum polycystum C. Agardh (Brown Seaweed)

492-498The phytochemical screening, nutritional composition and bioactive potential of Sargassum polycystum (Brown Seaweed) were investigated. The bioactive compounds of Sargassum polycystum showed significant activity against four human pathogens, namely, Bacillus subtilis, Escherichia coli, Staphylococcus aureus, and Klebsiella pneumoniae. The biochemical composition of Sargassum polycystum exhibited high nutritional potential of protein (14.2%), carbohydrate (25.0%), lipid (7.6%), fiber (21.3%), and ash (29.0%) than that in terrestrial plants and animal products. The Sargassum polycystum could be providing more opportunities for discovering new drugs which may be used as a source of healthy food for human regular diet

Scientific Validation of Ovulation Inducing, Gonodotrophic Releasing,and Anti-Oxidant Activities of Sambirani Poo Kuligai.

The study of anti Oxidant activities of sambirani poo kuligai, SAMBIRANI POO KULIGAI possessing ovulation inducing activities in many ways by inducing ovulation and maintains the hormone level have not been scientifically explored till now. So this is a right time to explore the nature of the drugs by using advanced research methodologies and techniques. To meet the Global Standard, this is a wonderful opportunity for validating Siddha medicinal preparation scientifically. Hence validating the efficacy of SAMBIRANI POO KULIGAI through my work will be an eye opener for this women society. Keeping in mind in building a strong nation, the research surely bears a valuable impact with it.The trial drug for the study Sambirani Poo Kuligai (SPK) from the literature “Agasthiyar Paripuranam 400” published by Rathna Nayaker and Sons for evaluation of ovulation inducing activity was done and the results boosted and promised to fill the women society for a safe medicinethe Sambirani Poo Kuligai is an excellent poly- herbal medicine in the treatment for anovulatory conditions like PCOS and the effect may be attributed to the elevation of the ovulation stimulatory hormones in animal models, Thus, this current analysis authenticates that Sambirani Poo Kuligai has impressive ovulogenic activity over PCOS (Soothaga vayu) in female, which exemplifies the intelligence of the Siddha literature to reach globally for the welfare of women society

Dynamic modelling reveals the separable contributions to achieving correct spindle orientation in a noisy system

The mechanisms by which the mammalian mitotic spindle is guided to a predefined orientation through microtubule-cortex interactions have recently received considerable interest, but there has been no dynamic model that describes spindle movements toward the preferred axis in human cells. Here, we develop a dynamic model based on stochastic activity of cues anisotropically positioned around the cortex of the mitotic cell and we show that the mitotic spindle does not reach equilibrium before chromosome segregation. Our model successfully captures the characteristic experimental behavior of noisy spindle rotation dynamics in human epithelial cells, including a weak underlying bias in the direction of rotation, suppression of motion close to the alignment axis, and the effect of the aspect ratio of the interphase cell shape in defining the final alignment axis. We predict that the force exerted per cue has a value that minimizes the deviation of the spindle from the predefined axis. The model has allowed us to systematically explore the parameter space around experimentally relevant configurations, and predict the mechanistic function of a number of established regulators of spindle orientation, highlighting how physical modeling of a noisy system can lead to functional biological understanding. We provide key insights into measurable parameters in live cells that can help distinguish between mechanisms of microtubule and cortical-cue interactions that jointly control the final orientation of the spindle.This work was supported by Cancer Research UKThis is the author accepted manuscript. The final version is available from Elsevier via http://dx.doi.org/10.1016/j.bpj.2015.08.01

Opportunities and challenges for deep learning in cell dynamics research

With the growth of artificial intelligence (AI), there has been an increase in the adoption of computer vision and deep learning (DL) techniques for the evaluation of microscopy images and movies. This adoption has not only addressed hurdles in quantitative analysis of dynamic cell biological processes, but it has also started supporting advances in drug development, precision medicine and genome-phenome mapping. Here we survey existing AI-based techniques and tools, and open-source datasets, with a specific focus on the computational tasks of segmentation, classification, and tracking of cellular and subcellular structures and dynamics. We summarise long-standing challenges in microscopy video analysis from the computational perspective and review emerging research frontiers and innovative applications for deep learning-guided automation for cell dynamics research

Base pressure fluctuations on typical missile configuration in presence of base cavity.

Pressure fluctuations in the base region of a typical missile configuration at a freestream Mach number of 0.7 are examined experimentally in the presence and absence of a base cavity. The objective was to characterize the pressure fluctuations and explain the influence of base cavities on their behavior. Experiments include unsteady pressure measurements at six azimuthal locations. Substantial variation in the characteristics of pressure fluctuations is noticed along the azimuthal direction due to the asymmetry of the model. The base cavities are seen to enhance the base pressure and reduce the root mean square of the pressure fluctuations. Higher-order moments show diminishing trend as the length of the base cavity is increased. Spectra in the absence of cavity exhibit three types of narrow-band tones based on the Strouhal number. Type I tones disapper from the spectra for small-length cavities, whereas type II tones get suppressed. On the other hand, for the large-length cavities, type I tones get enhanced, whereas type II tones disappear. Autocorrelation and cross-correlation plots exhibit a large-amplitude, low-frequency oscillation that exists even after large separation times for the larger-length cavities, and virtually no such oscillations are visible for the small-length-cavity models