Evaluation of in vitro antifungal activity of potassium bicarbonate on Rhizoctonia solani AG 4 HG-I, Sclerotinia sclerotiorum and Trichoderma sp.

The effect of increased concentrations of potassium bicarbonate (KHCO3) as a possible alternative to synthetic fungicides for controlling Rhizoctonia solani AG 4 HG-I and Sclerotinia sclerotiorum was evaluated in vitro, in this study. In addition, the effect of potassium bicarbonate on Trichoderma sp., a natural antagonist on R. solani AG 4 HG-I and S. sclerotiorum was determined. Potassium bicarbonate substantially inhibited (P<0.05) the growth of the three fungal strains. Mycelial growth of R. solani AG 4 HG-I significantly decreased as the concentration of bicarbonate increased, especially at concentrations greater than 200 mM. Similarly, mycelial growth of both S. sclerotiorum and Trichoderma sp. dramatically reduced in increasing concentrations of KHCO3. Mycelial growth of either fungi was completely inhibited when exposed to 100 mM bicarbonate. In addition, KHCO3 concentrations higher than 10 mM caused significant (P<0.05) reduction of the sclerotium formation of S. sclerotiorum. Also, sclerotium germination and de novo sclerotium formation were significantly inhibited as the concentrations of KHCO3 increased. As a result, it was concluded that potassium bicarbonate was an alternative chemical agent for  controlling R. solani AG 4 HG-I and S. sclerotiorum. Also, KHCO3 was found to have negative effects on Trichoderma sp.Key words: Antifungal effect, KHCO3, soil borne pathogens, sclerotium germination

Comparison of prognostic scores and surgical approaches to treat spinal metastatic tumors: A review of 57 cases

Surgical treatment of metastatic spinal cord compression with or without neural deficit is controversial. Karnofsky and Tokuhashi scores have been proposed for prognosis of spinal metastasis. Here, we conducted a retrospective analysis of Karnofsky and modified Tokuhashi scores in 57 consecutive patients undergoing surgery for secondary spinal metastases to evaluate the value of these scores in aiding decision making for surgery. Comparison of preoperative Karnofsky and modified Tokuhashi scores with the type of the surgical approach for each patient revealed that both scores not only reliably estimate life expectancy, but also objectively improved surgical decisions. When the general status of the patient is poor (i.e., Karnofsky score less than 40% or modified Tokuhashi score of 5 or greater), palliative treatments and radiotherapy, rather than surgery, should be considered

Ubiquitous molecular substrates for associative learning and activity-dependent neuronal facilitation.

Recent evidence suggests that many of the molecular cascades and substrates that contribute to learning-related forms of neuronal plasticity may be conserved across ostensibly disparate model systems. Notably, the facilitation of neuronal excitability and synaptic transmission that contribute to associative learning in Aplysia and Hermissenda, as well as associative LTP in hippocampal CA1 cells, all require (or are enhanced by) the convergence of a transient elevation in intracellular Ca2+ with transmitter binding to metabotropic cell-surface receptors. This temporal convergence of Ca2+ and G-protein-stimulated second-messenger cascades synergistically stimulates several classes of serine/threonine protein kinases, which in turn modulate receptor function or cell excitability through the phosphorylation of ion channels. We present a summary of the biophysical and molecular constituents of neuronal and synaptic facilitation in each of these three model systems. Although specific components of the underlying molecular cascades differ across these three systems, fundamental aspects of these cascades are widely conserved, leading to the conclusion that the conceptual semblance of these superficially disparate systems is far greater than is generally acknowledged. We suggest that the elucidation of mechanistic similarities between different systems will ultimately fulfill the goal of the model systems approach, that is, the description of critical and ubiquitous features of neuronal and synaptic events that contribute to memory induction

The opinions of middle school mathematics teachers on the integration of mathematics course and social issues

The purpose of this study is to examine the opinions of middle school mathematics teachers on the integration of mathematics course and social issues. For this purpose, qualitative research method was used in this study. As for determining the participants of the research, criterion sampling among purposeful sampling methods was used. Being a middle school mathematics teacher as an occupation was considered as a criterion for determining the participants. The participants of the research consist of 13 middle school mathematics teachers in Turkey. So as to collect the research data, the semi-structured interview form created by the researchers was used. The data analysis was performed according to the content analysis, and Nvivo 10 program was used for the analysis. As a result of this study, the themes of the situation and methods of the integration of mathematics course and social issues, the attainment of democratic values in mathematics course and the ways of its attainment, gaining awareness of social justice and equality in mathematics course and the ways of its gaining, the activities performed by teachers for social issues in mathematics course and the teachers’ suggestions for the integration of mathematics course and social issues were reached and the results were discussed within this frame. © 2018 Eurasian Society of Educational Research. All rights reserved

Ultrasonographic Evaluation Of Sciatic Nerves In Patients With Spinal Cord Injury

Study design: Cross-sectional, controlled study. Objective: To evaluate the sciatic nerves of subjects with spinal cord injury (SCI) by using ultrasound (US) imaging and to explore whether US measurements are associated with clinical and electrophysiological findings. Setting: National Rehabilitation Center in Ankara, Turkey. Methods: Fifteen SCI subjects (12 male (M), 3 female (F)) and 23 (16 M, 7 F) healthy controls were included in the study. After clinical assessment of the subjects, lower limb nerve conduction studies and US imaging of the sciatic nerves were performed. Cross-sectional area (CSA) values of the sciatic nerves were correlated with the clinical and electrophysiologic data. Results: Mean CSA values were lower in the patient group when compared with the control group (P=0.042). Reduced compound motor action potentials regarding tibial and peroneal nerves were observed in the patient group (P=0.003 and P=0.005, respectively). US measurements did not correlate with the electrophysiological findings. However, sciatic nerve CSA values were positively correlated with body mass index in the control (r = 0.534, P < 0.05) and patient (r=0.482, P < 0.05) groups. Conclusion: Sciatic nerves seem to be smaller in subjects with SCI. Together with our electrophysiological data, this preliminary finding could possibly be attributed to primary axonal loss.WoSScopu