230 research outputs found

    Eigenmode excitation of Alfven ion cyclotron instability

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    科研費報告書収録論文(課題番号:07558072・基盤研究(A)(2)・H7~H9/研究代表者:犬竹, 正明/高密度プラズマ源を用いた電磁流体工学試験装置の開発

    Measurement of ICRF waves in the GAMMA10 tandem mirror using reflectometers

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    科研費報告書収録論文(課題番号:07458088・基盤研究(B)(2)・H7~H8/研究代表者:犬竹, 正明/マイクロ波反射計とプローブ計測による密度および磁場揺動径方向分布の比較

    Structure of HrcQ(B)-C, a conserved component of the bacterial type III secretion systems

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    Type III secretion systems enable plant and animal bacterial pathogens to deliver virulence proteins into the cytosol of eukaryotic host cells, causing a broad spectrum of diseases including bacteremia, septicemia, typhoid fever, and bubonic plague in mammals, and localized lesions, systemic wilting, and blights in plants. In addition, type III secretion systems are also required for biogenesis of the bacterial flagellum. The HrcQ(B) protein, a component of the secretion apparatus of Pseudomonas syringae with homologues in all type III systems, has a variable N-terminal and a conserved C-terminal domain (HrcQ(B)-C). Here, we report the crystal structure of HrcQ(B)-C and show that this domain retains the ability of the full-length protein to interact with other type III components. A 3D analysis of sequence conservation patterns reveals two clusters of residues potentially involved in protein–protein interactions. Based on the analogies between HrcQ(B) and its flagellum homologues, we propose that HrcQ(B)-C participates in the formation of a C-ring-like assembly

    The Collins-Roscoe mechanism and D-spaces

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    We prove that if a space X is well ordered (αA)(\alpha A), or linearly semi-stratifiable, or elastic then X is a D-space

    We Heal as One: Interprofessional Health Collaboration During the Covid-19 Pandemic

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    A collaborative healthcare system enabled through multi-professional and interprofessional partnerships that pave the way to improved health outcomes has been the director of the Millennium Development Goals (World Health Organization, 2016). But the occurrence of the global COVID-19 pandemic challenged the healthcare system in unprecedented ways. This study explored the essence of interprofessional collaboration among medical and paramedical healthcare professionals. A phenomenological research study through photovoice was employed and analyzed using thematic analysis. Study corpus was gathered from a total of 15 participants, including three medical technologists, three nutritionists and dieticians, three radiologic technologists, three pharmacists, two nurses, and one physician. Four themes surfaced from the responses, namely: unity in diversity, paradigm shift, parallel dilemmas, and resilient optimism. Keywords: healthcare system, interprofessional collaboration, medical, healthcar

    High-density plasma production with potential confinement in the GAMMA 10 tandem mirror

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    The improvement of potential confinement was attained in the GAMMA 10 tandem mirror [Phys. Rev. Lett. 55, 939 (1985); Proceedings of the 13th International Conference on Plasma Physics and Controlled Nuclear Fusion Research, Washington, 1990 (International Atomic Energy Agency, Vienna, 1991), Vol. 2, p. 539] by axisymmetrization of heating systems for the plasma production, heating, and potential formation. A significant increase of the density and diamagnetism by the potential confinement was observed. In the previous experiment, it was difficult to increase the central cell density higher than 2.7×1018 m–3. One of the possible mechanisms is the density clamping due to the eigenmode formation of the ion–cyclotron-range of frequency (ICRF) waves in the axial direction. With high harmonic ICRF waves (RF3), the experiments to overcome this problem have been performed. In preliminary experiments with RF3 and NBI the maximum density of 4×1018 m–3 was attained

    Genomics of Aspergillus oryzae: Learning from the History of Koji Mold and Exploration of Its Future

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    At a time when the notion of microorganisms did not exist, our ancestors empirically established methods for the production of various fermentation foods: miso (bean curd seasoning) and shoyu (soy sauce), both of which have been widely used and are essential for Japanese cooking, and sake, a magical alcoholic drink consumed at a variety of ritual occasions, are typical examples. A filamentous fungus, Aspergillus oryzae, is the key organism in the production of all these traditional foods, and its solid-state cultivation (SSC) has been confirmed to be the secret for the high productivity of secretory hydrolases vital for the fermentation process. Indeed, our genome comparison and transcriptome analysis uncovered mechanisms for effective degradation of raw materials in SSC: the extracellular hydrolase genes that have been found only in the A. oryzae genome but not in A. fumigatus are highly induced during SSC but not in liquid cultivation. Also, the temperature reduction process empirically adopted in the traditional soy-sauce fermentation processes has been found to be important to keep strong expression of the A. oryzae-specific extracellular hydrolases. One of the prominent potentials of A. oryzae is that it has been successfully applied to effective degradation of biodegradable plastic. Both cutinase, responsible for the degradation of plastic, and hydrophobin, which recruits cutinase on the hydrophobic surface to enhance degradation, have been discovered in A. oryzae. Genomic analysis in concert with traditional knowledge and technology will continue to be powerful tools in the future exploration of A. oryzae
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