53 research outputs found
Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming
Tex19.1 Inhibits the N-End Rule Pathway and Maintains Acetylated SMC3 Cohesin and Sister Chromatid Cohesion in Oocytes
Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
Second trimester amniotic fluid bisphenol A concentration is associated with decreased birth weight in term infants
Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway
Arrest at the diplotene stage of meiotic prophase I is delayed by progesterone but is not required for primordial follicle formation in mice
Bisphenol A in eggs causes development-specific liver molecular reprogramming in two generations of rainbow trout
Urinary bisphenol A and semen quality, the LIFE Study
Bisphenol A (BPA), a high-production volume industrial chemical found in several consumer products, has been negatively associated with sperm quality. This study aimed to estimate the association between BPA and 35 measures of semen quality among reproductive aged men recruited from 16 counties in Michigan and Texas, 2005–2009. Of 501 enrolled males, 418 (83.4%) provided a urine sample and at least one semen sample. Linear and logistic regression models assessed the association between urinary BPA levels and individual semen quality endpoints. Generalized Estimating Equations were used to account for repeated measures of semen quality and adjusted models accounted for 11 a priori covariates. Geometric mean total urinary BPA concentration among participants was 0.55 ng/mL (95% CI 0.49–0.63). A negative relation between BPA and DNA fragmentation was the sole significant finding in adjusted linear regression (β=−0.0544, p=0.035) and suggestive of less sperm DNA damage
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