1,009 research outputs found
Sports review: A content analysis of the International Review for the Sociology of Sport, the Journal of Sport and Social Issues and the Sociology of Sport Journal across 25 years
The International Review for the Sociology of Sport, the Journal of Sport and Social Issues and Sociology of Sport Journal have individually and collectively been subject to a systematic content analysis. By focusing on substantive research papers published in these three journals over a 25-year time period it is possible to identify the topics that have featured within the sociology of sport. The purpose of the study was to identify the dominant themes, sports, countries, methodological frameworks and theoretical perspectives that have appeared in the research papers published in these three journals. Using the terms, identified by the author(s), that appear in the paperâs title, abstract and/or listed as a key word, subject term or geographical term, a baseline is established to reflect on the development of the sub-discipline as represented by the content of these three journals. It is suggested that the findings illustrate what many of the more experienced practitioners in the field may have felt subjectively. On the basis of this systematic, empirical study it is now possible to identify those areas have received extensive coverage and those which are under-researched within the sociology of sport. The findings are used to inform a discussion of the role of academic journals and the recent contributions made by Michael Silk, David Andrews, Michael Atkinson and Dominic Malcolm on the past, present and future of the âsociology of sportâ
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The theory of international business: the role of economic models
This paper reviews the scope for economic modelling in international business studies. It argues for multi-level theory based on classic internalisation theory. It present a systems approach that encompasses both firm-level and industry-level analysis
Palacio de justicia de Lille â Francia
The article provides a general description of this important building, and also a more detailed discussion of particular aspects of it.
There is also a technical commentary of the structure, both in its general and particular nature, and the architectural as well as aesthetic aspects if it are considered.
The whole design has formal and structural features that are unusual and noteworthy.Se describe el conjunto total y después se especifican las par tes del edificio del Palacio de Justicia, señalando las dependencias que contiene y la función de cada una.
En una segunda parte del artĂculo se comenta tĂ©cnicamente la estructura de la obra, tambiĂ©n por partes y segĂșn su nivel, dando, a la vez, detalles arquitectĂłnicos y estĂ©ticos.
El conjunto edificado reĂșne caracterĂsticas especĂficas formales y estructurales que lo destacan y hacen digno de especial atenciĂłn y menciĂłn
Transforming growth factor- directly induces p53-up-regulated modulator of apoptosis (PUMA) during the rapid induction of apoptosis in myc-driven B-cell lymphomas
Background: TGF-ÎČ induces apoptosis in Burkitt's lymphoma cells.
Results: PUMA is a direct target gene of TGF-ÎČ signaling and is required for rapid apoptosis.
Conclusion: TGF-ÎČ-mediated direct induction of PUMA contributes to apoptosis in human and murine c-Myc-driven lymphomas.
Significance: These studies link TGF-ÎČ signaling and transcriptional activation of PUMA, two factors with critical roles in regulating B-cell survival
Edith T. Penrose: Economist of âThe Ordinary Business of Lifeâ
When Edith T. Penrose became Fritz Machlupâs student in the late-1940s, she found little in mainstream or Austrian economics to guide her as she began her explorations into the growth of the firm. While she acknowledged Kenneth Bouldingâs influence on her work, we suspect she drew on a broader tradition that includes, among others, Alfred Marshall, Frank Knight (Bouldingâs teacher), and Ronald Coase. We seek to demonstrate Penroseâs connection to this âinvisible collegeâ, particularly to Knight, and its influence on her investigation of the growth of the firm. Given mainstream economistsâ pursuit of rigor at the expense of practical relevance and their continuing inattention to Coaseâs work, we suggest Penroseâs work on the growth of the firm can be understood as part of a broader tradition represented by this âinvisible collegeâ, lending to useful new insights for business strategy and business ethics scholarship
Edith T. Penrose: Economist of "The Ordinary Business of Life"
When Edith T. Penrose became Fritz Machlupâs student in the late-1940s, she found little in mainstream or Austrian economics to guide her as she began her explorations into the growth of the firm. While she acknowledged Kenneth Bouldingâs influence on her work, we suspect she drew on a broader tradition that includes, among others, Alfred Marshall, Frank Knight (Bouldingâs teacher), and Ronald Coase. We seek to demonstrate Penroseâs connection to this âinvisible collegeâ, particularly to Knight, and its influence on her investigation of the growth of the firm. Given mainstream economistsâ pursuit of rigor at the expense of practical relevance and their continuing inattention to Coaseâs work, we suggest Penroseâs work on the growth of the firm can be understood as part of a broader tradition represented by this âinvisible collegeâ, leading to useful new insights for business strategy and business ethics scholarship
Discourse and identity in a corpus of lesbian erotica
This article uses corpus linguistic methodologies to explore representations of lesbian desires and identities in a corpus of lesbian erotica from the 1980s and 1990s. We provide a critical examination of the ways in which âlesbian gender,â power, and desire are represented, (re-)produced, and enacted, often in ways that challenge hegemonic discourses of gender and sexuality. By examining word frequencies and collocations, we critically analyze some of the themes, processes, and patterns of representation in the texts. Although rooted in linguistics, we hope this article provides an accessible, interdisciplinary, and timely contribution toward developing understandings of discursive practices surrounding gender and sexuality
Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells
Epstein-Barr virus (EBV) is implicated in the pathogenesis of multiple human tumours of lymphoid and epithelial origin. The virus infects and immortalizes B cells establishing a persistent latent infection characterized by varying patterns of EBV latent gene expression (latency 0, I, II and III). The CDK1 activator, Response Gene to Complement-32 (RGC-32, C13ORF15), is overexpressed in colon, breast and ovarian cancer tissues and we have detected selective high-level RGC-32 protein expression in EBV-immortalized latency III cells. Significantly, we show that overexpression of RGC-32 in B cells is sufficient to disrupt G2 cell-cycle arrest consistent with activation of CDK1, implicating RGC-32 in the EBV transformation process. Surprisingly, RGC-32 mRNA is expressed at high levels in latency I Burkitt's lymphoma (BL) cells and in some EBV-negative BL cell-lines, although RGC-32 protein expression is not detectable. We show that RGC-32 mRNA expression is elevated in latency I cells due to transcriptional activation by high levels of the differentially expressed RUNX1c transcription factor. We found that proteosomal degradation or blocked cytoplasmic export of the RGC-32 message were not responsible for the lack of RGC-32 protein expression in latency I cells. Significantly, analysis of the ribosomal association of the RGC-32 mRNA in latency I and latency III cells revealed that RGC-32 transcripts were associated with multiple ribosomes in both cell-types implicating post-initiation translational repression mechanisms in the block to RGC-32 protein production in latency I cells. In summary, our results are the first to demonstrate RGC-32 protein upregulation in cells transformed by a human tumour virus and to identify post-initiation translational mechanisms as an expression control point for this key cell-cycle regulator
Salt-inducible kinases (SIKs) regulate TGFÎČ-mediated transcriptional and apoptotic responses
Anisotropic Colossal Magnetoresistance Effects in Fe_{1-x}Cu_xCr_2S_4
A detailed study of the electronic transport and magnetic properties of
FeCuCrS () on single crystals is presented. The
resistivity is investigated for K in magnetic fields up to
14 Tesla and under hydrostatic pressure up to 16 kbar. In addition
magnetization and ferromagnetic resonance (FMR) measurements were performed.
FMR and magnetization data reveal a pronounced magnetic anisotropy, which
develops below the Curie temperature, , and increases strongly
towards lower temperatures. Increasing the Cu concentration reduces this
effect. At temperatures below 35 K the magnetoresistance, , exhibits a strong dependence on the direction of the
magnetic field, probably due to an enhanced anisotropy. Applying the field
along the hard axis leads to a change of sign and a strong increase of the
absolute value of the magnetoresistance. On the other hand the
magnetoresistance remains positive down to lower temperatures, exhibiting a
smeared out maximum with the magnetic field applied along the easy axis. The
results are discussed in the ionic picture using a triple-exchange model for
electron hopping as well as a half-metal utilizing a band picture.Comment: some typos correcte
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