Improvement and implementation of a national individual care plan in paediatric palliative care: a study protocol

INTRODUCTION: Paediatric palliative care (PPC) is care for children with life-threatening or life-limiting conditions, and can involve complex high-tech care, which can last for months or years. In 2015, the National Individual Care Plan (ICP) for PPC was developed and has shown to be successful. The ICP can be seen as an instrument to facilitate coordination, quality and continuity of PPC. However, in practice, an ICP is often completed too late and for too few children. We aim to improve the coordination, quality and continuity of care for every child with a life-threatening or life-limiting condition and his/her family by further developing and implementing the ICP in the Netherlands. METHODS AND ANALYSIS: To evaluate the original ICP, ICP 1.0, interviews and questionnaires will be held among parents of children who have or have had an ICP 1.0 and healthcare professionals (HCPs) who used ICP 1.0. Based on the results, ICP 1.0 will be further developed. An implementation strategy will be written and the renewed ICP, ICP 2.0, will be nationally tested in an implementation period of approximately 7 months. During the implementation period, ICP 2.0 will be used for all children who are registered with Children’s Palliative Care teams. After the implementation period, ICP 2.0 will be evaluated using interviews and questionnaires among parents of children who received ICP 2.0 and HPCs who worked with ICP 2.0. Based on these results, ICP 2.0 will be further optimised into the final version: ICP 3.0. ETHICS AND DISSEMINATION: This study received ethical approval. The ICP 3.0 will be disseminated through the Dutch Centre of Expertise in Children’s Palliative Care, to ensure wide availability for the general public and HCPs within PPC. Additionally, we aim to publish study results in open-access, peer-reviewed journals and to present results at national and international scientific meetings

Effecten van het rapen van oesters in de Waddenzee op de benthosgemeenschap en vogelpopulatie

Eind 2009 en begin 2010 zijn er door de Provincie Fryslân een 18-tal vergunningen verleend voor het experimenteel commercieel handmatig rapen van oesters voor een periode van 4 jaar. Omdat oesterrapen een nieuwe activiteit is in de Waddenzee is nog niet bekend of deze activiteit negatieve effecten heeft op Natura 2000 instandhoudingsdoelstellingen. Het gaat dan met name om habitattype H1140-A (Slik- en zandplaten, getijdengebieden) en verschillende vogelsoorten die foerageren op mossel- en oesterbanken

Application of biostimulant products and biological control agents in sustainable viticulture: A review

Current and continuing climate change in the Anthropocene epoch requires sustainable agricultural practices. Additionally, due to changing consumer preferences, organic approaches to cultivation are gaining popularity. The global market for organic grapes, grape products, and wine is growing. Biostimulant and biocontrol products are often applied in organic vineyards and can reduce the synthetic fertilizer, pesticide, and fungicide requirements of a vineyard. Plant growth promotion following application is also observed under a variety of challenging conditions associated with global warming. This paper reviews different groups of biostimulants and their effects on viticulture, including microorganisms, protein hydrolysates, humic acids, pyrogenic materials, and seaweed extracts. Of special interest are biostimulants with utility in protecting plants against the effects of climate change, including drought and heat stress. While many beneficial effects have been reported following the application of these materials, most studies lack a mechanistic explanation, and important parameters are often undefined (e.g., soil characteristics and nutrient availability). We recommend an increased study of the underlying mechanisms of these products to enable the selection of proper biostimulants, application methods, and dosage in viticulture. A detailed understanding of processes dictating beneficial effects in vineyards following application may allow for biostimulants with increased efficacy, uptake, and sustainability.KJ wishes to acknowledge financial support (3710473400); MS-M thanks to RTI2018-099417-B-I00 (Spanish Ministry of Science, Innovation and Universities cofunded with EU FEDER funds); JB wish to acknowledge the Conselho Nacional de Desenvolvimento Científico e Tecnológico/Brasil (CNPQ process number 309477/2021-2); RO-H is supported by the Ramón y Cajal program from the MICINN (RYC-2017 22032), PAIDI 2020 (Ref. 20_00323), AEI GGOO 2020 (GOPC-CA-20-0001), “José Castillejo” program from the “Ministerio de Universidades” (CAS21/00125) and PID2019-106004RA-I00/AEI/10.13039/501100011033. SM and GT thanks to Ministerio de Ciencia e Innovación (grant PID2020-114330GB-100). PAIDI2020 from Junta de Andalucía, grant P18-RT-1401 to SM, MD, and GT is also acknowledged. GT acknowledge the support of the publication fee by the CSIC Open Access Publication Support Initiative through its Unit of Information Resources for Research (URICI)

De ontwikkeling van niet beviste sublitorale mosselbanken 2009 - 2012

In de Nederlandse kustwateren vindt mosselzaadvisserij en mosselkweek plaats. Deze wateren herbergen echter belangrijke natuurwaarden en de meeste wateren zijn derhalve aangewezen als natuurgebied, wat Nederland verplicht om er voor te zorgen dat de natuurwaarden in deze gebieden in stand blijven. Verbetering van de kwaliteit is vooral mogelijk ten aanzien van bodemfauna en de vorming van biogene structuren met mossels (en de daaraan geassocieerde biodiversiteit). Het is in de Waddenzee echter niet goed bekend hoe gesloten (i.e. onbeviste) sublitorale mosselzaadbanken zich ontwikkelen in de tijd en welke specifieke natuurwaarden ze herbergen. Om hier inzicht in te verkrijgen is een monitorprogramma, welke loopt van 2010 t/m 2013, opgesteld waarin gesloten sublitorale mosselbanken gevolgd worden

Toestand vis en visserij in de zoete Rijkswateren. Deel II: Methoden

Sinds 2013 worden al deze monitoringprogramma’s jaarlijks in één rapportage gebundeld. Dit rapport bevat de gebruikte methodieken van de verschillende vis-monitoringsprogramma’s in de zoete Rijkswatere

Degradation of haloaromatic compounds

An ever increasing number of halogenated organic compounds has been produced by industry in the last few decades. These compounds are employed as biocides, for synthetic polymers, as solvents, and as synthetic intermediates. Production figures are often incomplete, and total production has frequently to be extrapolated from estimates for individual countries. Compounds of this type as a rule are highly persistent against biodegradation and belong, as "recalcitrant" chemicals, to the class of so-called xenobiotics. This term is used to characterise chemical substances which have no or limited structural analogy to natural compounds for which degradation pathways have evolved over billions of years. Xenobiotics frequently have some common features. e.g. high octanol/water partitioning coefficients and low water solubility which makes for a high accumulation ratio in the biosphere (bioaccumulation potential). Recalcitrant compounds therefore are found accumulated in mammals, especially in fat tissue, animal milk supplies and also in human milk. Highly sophisticated analytical techniques have been developed for the detection of organochlorines at the trace and ultratrace level

Biophysical interactions in tropical agroforestry systems

sequential systems, simultaneous systems Abstract. The rate and extent to which biophysical resources are captured and utilized by the components of an agroforestry system are determined by the nature and intensity of interac-tions between the components. The net effect of these interactions is often determined by the influence of the tree component on the other component(s) and/or on the overall system, and is expressed in terms of such quantifiable responses as soil fertility changes, microclimate modification, resource (water, nutrients, and light) availability and utilization, pest and disease incidence, and allelopathy. The paper reviews such manifestations of biophysical interactions in major simultaneous (e.g., hedgerow intercropping and trees on croplands) and sequential (e.g., planted tree fallows) agroforestry systems. In hedgerow intercropping (HI), the hedge/crop interactions are dominated by soil fertility improvement and competition for growth resources. Higher crop yields in HI than in sole cropping are noted mostly in inherently fertile soils in humid and subhumid tropics, and are caused by large fertility improvement relative to the effects of competition. But, yield increases are rare in semiarid tropics and infertile acid soils because fertility improvement does not offse