830 research outputs found

    The Opioid Crisis in Rural and Small Town America

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    In this brief, authors Shannon Monnat and Khary Rigg examine rural versus urban differences in opioid mortality and identify challenges for dealing with the opioid crisis in rural areas. They report that, in 2016, opioid mortality rates were higher in urban than in rural counties, particularly in the Midwest, but rates have increased more in rural than in urban counties over the past two decades. Since 2010, the share of drug overdose deaths involving prescription opioids has declined, but the share of deaths involving heroin and synthetic opioids has spiked in both rural and urban areas. The most dramatic increases in opioid deaths were in the rural Midwest, where they were 16 times higher in 2016 than in 1999, and in the rural Northeast, where they were 11.4 times higher. Prescription opioids are involved in a larger share of rural than urban drug overdose deaths, whereas heroin and synthetic opioids (such as fentanyl) account for a larger share of urban deaths. Over half of drug overdose deaths involve multiple drugs. Policy initiatives to date have been largely ineffective at addressing the opioid crisis in many of the hardest-hit rural communities, and the recent surge in fentanyl overdoes in large urban areas may be a precursor of what to expect in at-risk rural communities in the coming years. Existing interventions are unlikely to be effective without addressing the underlying social and economic factors that are plaguing the hardest-hit areas

    Rural Adolescents Are More Likely Than Their Urban Peers to Abuse Prescription Painkillers

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    U.S. media and popular culture historically portrayed drug abuse as an urban problem, but in recent years, there has been more media attention on rural drug issues. Part of this growing attention pertains to the growing epidemic of narcotic painkiller abuse in rural America. Although all areas of the country experienced increases in painkiller prescribing, abuse, and mortality over the past two decades, the increases have been most pronounced in small towns and rural areas. This rural drug epidemic requires immediate attention from policy makers and practitioners

    Tacrolimus and Mycophenolate Mofetil as Maintenance Immunosuppressants

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    The Indian Ocean tsunami: socio-economic impacts in Thailand

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    On the morning of 26 December 2004 large areas of coastal southern Thailand were transformed when a tsunami, generated by a powerful submarine earthquake in the Indian Ocean, swept ashore. Officially, there were 5395 confirmed deaths in Thailand with another 2932 people listed as missing. In February 2005 a team led by Dr Ben Horton of the University of Pennsylvania was awarded an SGER grant by the National Science Foundation to undertake exploratory research on the tsunami in Malaysia and Thailand. This report summarizes the preliminary conclusions of the social science element of the Thai fieldwork. The team undertook fieldwork in three main sites during July 2005: Koh Lanta, Koh Phi Phi and Khao Lak. We chose Koh Phi Phi as a small, tourist (backpacker)-oriented island economy with high levels of damage and casualties; Koh Lanta as a site with a significant population of fisherfolk with a long presence in the area; and Khao Lak as a mainland site with the highest number of casualties in Thailand and with a mixed tourism-fishing economy

    A review of juvenile redclaw crayfish Cherax quadricarinatus (von Martens, 1898) Aquaculture: global production practices and innovation

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    The Australian Redclaw crayfish, Cherax quadricarinatus, has been the subject of aquaculture development for more than 3 decades. Farm production from Australia and from around the world for this species has been relatively low, as suitable production technology continues to develop. The production of redclaw juveniles for the purpose of stocking to ponds for on-growing to marketable size, has been a particular constraint and new approaches to breeding and mass production of craylings have provided renewed impetus to industry expansion. This paper reviews the literature concerning redclaw juvenile production and provides a status report of current practices and innovations that may support further expansion of redclaw aquaculture

    Understanding Opioid Users’ Views on Fentanyl could help Reduce Overdoses

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    The opioid overdose crisis is a national public health emergency, made much worse in recent years by the widespread emergence of fentanyl – a highly potent synthetic opioid. This research brief summarizes the findings from their research conducted in southwestern Pennsylvania in 2017 and 2018. Results show that the majority of interviewees who use opioids are fearful of and want to avoid fentanyl and would utilize harm reduction strategies such as fentanyl test strips if they were made more widely available

    The Stories behind the Struggle: A Closer Look at First Experiences with Opioid Misuse

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    The opioid crisis is a national public health emergency. Over 47,000 people in the U.S. died of opioid overdoses in 2017. Improving our knowledge about how people first come to misuse opioids can help to inform prevention and treatment interventions. This research brief shows that opioid misuse most often begins before age 25, most people obtain the opioids they misuse from friends and family rather than a health care provider, and experimenting and coping with life stressors are the most common motivations for starting opioid misuse

    Determining suitable thermal regimes for early instar redclaw juveniles, Cherax quadricarinatus (von Martens, 1868) (Decapoda, Parastacidae), for a proposed nursery phase

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    Modern, intensified aquaculture typically involves three production phases; hatchery, nursery, and grow-out. For redclaw crayfish aquaculture however, such delineation has been ill-defined. Farming of redclaw was initiated based on the putative beneficial physical and biological attributes of the species, which suggested production methods would be relatively simple. The simple approach proved to be inefficient and only partially effective, which hindered industry development. Hatchery technology now exists to supply seed stock for grow-out, but hatchery production is variable, and the performance of hatchery reared juveniles is inconsistent. A nursery phase has been proposed between hatchery production and grow-out of approximately 3 weeks duration, sufficient to allow 2 or more moults. An important primary parameter in the proposed nursery phase is the thermal regime that will support optimum survival and growth. This study quantified the effect of temperature on the growth and survival of redclaw juveniles for a 22-day nursery phase. Temperature had a statistically significant effect on the survival of juveniles, whereby, the high temperatures were associated with high mortality, and the lower temperature treatments were associated with very low mortality. Survival was 98 to 100% for craylings held at temperatures between 18 degrees C and 22 degrees C, and between 0% and 6% for craylings at temperature treatments of 25 degrees C to 32 degrees C. Mortalities within treatments between 25 degrees C and 30 degrees C, primarily occurred from day six to day eleven, corresponding with the initiation of moulting. Change of mass of crayfish was significantly higher with increasing temperature between 18 degrees C and 22 degrees C and at individual weights that suggest they had completed a moult. This study suggests a water temperature of 22 degrees C is optimal for survival and growth in a nursery phase

    The Stories behind the Struggle: A Closer Look at First Experiences with Opioid Misuse

    Get PDF
    The opioid crisis is a national public health emergency. Over 47,000 people in the U.S. died of opioid overdoses in 2017. Improving our knowledge about how people first come to misuse opioids can help to inform prevention and treatment interventions. This research brief shows that opioid misuse most often begins before age 25, most people obtain the opioids they misuse from friends and family rather than a health care provider, and experimenting and coping with life stressors are the most common motivations for starting opioid misuse
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