Diagnostic ability and capacity of optical coherence tomography-angiography to detect retinal and vascular changes in patients with fibromyalgia

Background. To evaluate the neuroretina and retinal vasculature of fibromyalgia (FM) patients and calculate a linear discriminant function (LDF) to improve retinal parameters’ contribution to FM diagnosis. Methods. Fifty FM patients and 232 healthy controls underwent retinal evaluation using swept-source optical coherence tomography (SS-OCT) angiography (Triton plus; Topcon) and spectral domain OCT (SD-OCT) (Spectralis; Heidelberg). The macular (m) and peripapillary (p) retinal nerve fibre layer (RNFL) and ganglion cell layer (GCL) were assessed, as was the macular vascular density. A logistic regression analysis was performed, and an LDF was calculated to evaluate OCT’s contribution to FM diagnosis. Results. With Triton OCT, the patients presented pRNFL thinning in the temporal sector (). Spectralis OCT measurements showed decreased pRNFL in patients in the following sectors: superonasal, ; nasal, ; inferonasal, ; temporal, ; and inferotemporal, . No significant differences were observed in the macular vascular plexus between patients and controls. However, vascular density in the superior sector showed a strong inverse correlation with disease duration (r = −0.978, ). The LDF calculated for Spectralis OCT yielded an area under the ROC curve of 0.968. Conclusions. FM patients present RNFL thinning observable using SS- and SD-OCT. However, these patients show similar vascular density in the macular area to healthy controls. The LDF that combines several RNFL parameters obtained using Spectralis OCT gives this device a powerful ability to differentiate between healthy individuals and individuals with FM

Inoculum sources and Preservation in Soils of Phytophthora parasitica from Cherry Tomato in Continental Crop Areas in Southeast Spain

Inoculum sources and Preservation in Soils of Phytophthora parasitica from Cherry Tomato in Continental Crop Areas in Southeast Spai

The Large Aperture GRB Observatory

The Large Aperture GRB Observatory (LAGO) is aiming at the detection of the high energy (around 100 GeV) component of Gamma Ray Bursts, using the single particle technique in arrays of Water Cherenkov Detectors (WCD) in high mountain sites (Chacaltaya, Bolivia, 5300 m a.s.l., Pico Espejo, Venezuela, 4750 m a.s.l., Sierra Negra, Mexico, 4650 m a.s.l). WCD at high altitude offer a unique possibility of detecting low gamma fluxes in the 10 GeV - 1 TeV range. The status of the Observatory and data collected from 2007 to date will be presented.Comment: 4 pages, proceeding of 31st ICRC 200

Water Cherenkov Detectors response to a Gamma Ray Burst in the Large Aperture GRB Observatory

In order to characterise the behaviour of Water Cherenkov Detectors (WCD) under a sudden increase of 1 GeV - 1 TeV background photons from a Gamma Ray Burst (GRB), simulations were conducted and compared to data acquired by the WCD of the Large Aperture GRB Observatory (LAGO). The LAGO operates arrays of WCD at high altitude to detect GRBs using the single particle technique. The LAGO sensitivity to GRBs is derived from the reported simulations of the gamma initiated particle showers in the atmosphere and the WCD response to secondaries.Comment: 5 pages, proceeding of the 31st ICRC 200

The 2.3 GHz continuum survey of the GEM project

We present a partial-sky survey of the radio continuum at 2.3 GHz within the scope of the Galactic Emission Mapping (GEM) project, an observational program conceived and developed to reveal the large-scale properties of Galactic synchrotron radiation through a set of self-consistent surveys of the radio continuum between 408 MHz and 10 GHz. The GEM experiment uses a portable and double-shielded 5.5-m radiotelescope in altazimuthal configuration to map 60-degree-wide declination bands from different observational sites by circularly scanning the sky at zenithal angles of 30 deg from a constantly rotating platform. The observations were accomplished with a total power receiver, whose front-end High Electron Mobility Transistor (HEMT) amplifier was matched directly to a cylindrical horn at the prime focus of the parabolic reflector. The Moon was used to calibrate the antenna temperature scale and the preparation of the map required direct subtraction and destriping algorithms to remove ground contamination as the most significant source of systematic error. We used 484 hours of total intensity observations from two locations in Colombia and Brazil to yield 66% sky coverage from DEC = -51.73 deg to DEC = +34.78 deg. The zero-level uncertainty of the combined survey is 103 mK with a temperature scale error of 5% after direct correlation with the Rhodes/HartRAO survey at 2326 MHz on a T-T plot. The sky brightness distribution into regions of low and high emission in the GEM survey is consistent with the appearance of a transition region as seen in the Haslam 408 MHz and WMAP K-band surveys. Preliminary results also show that the temperature spectral index between 408 MHz and the 2.3 GHz band of the GEM survey has a weak spatial correlation with these regions; but it steepens significantly from high to low emission regions with respect to the WMAP K-band survey.Comment: 20 pages, 21 figures, 6 tables. Extensively revised and enlarged version accepted for publication in Astronomy & Astrophysics. Smaller figure

Lepton Number and Lepton Flavor Violation through Color Octet States

We discuss neutrinoless double beta decay and lepton flavor violating decays such as $\mu-> e\gamma$ in the colored seesaw scenario. In this mechanism, neutrino masses are generated at one-loop via the exchange of TeV-scale fermionic and scalar color octets. The same particles mediate lepton number and flavor violating processes. We show that within this framework a dominant color octet contribution to neutrinoless double beta decay is possible without being in conflict with constraints from lepton flavor violating processes. We furthermore compare the "direct" color octet contribution to neutrinoless double beta decay with the "indirect" contribution, namely the usual standard light Majorana neutrino exchange. For degenerate color octet fermionic states both contributions are proportional to the usual effective mass, while for non-degenerate octet fermions this feature is not present. Depending on the model parameters, either of the contributions can be dominant.Comment: 17 pages, 16 figure