Valores de referencia en el número de autores en las mejores publicaciones de revistas científicas en el área de las ciencias de la actividad física y del deporte

The purpose of this study is to analyze the number of authors of the articles in the sciences of physical activity and sport in the Web of Science. Ten artices with more citations of the 10 journals with the highest impact factor in 2012 (JCR), the thematic area «Sport Science» and the 10 articles with more citations of the 10 related journals were analyzed sports science, with highest impact in 2012 (JCR) of area «Hospitality Leisure sport Tourism». The most significant results indicated that: a) the average number of authors in the journals of the subject area «Sport Science», is 3-4 authors, while in the related sports science journals Area «Hospitality Leisure Sport Tourism «is between 2-3 authors. These data may serve as reference both evaluators as assessed in different criteria.El propósito del presente estudio es analizar el número de autores de los principales artículos relacionados con las ciencias de la actividad física y del deporte de la Web of Science. Para ello se analizaron los 10 artículos con mayor número de citas de las 10 revistas con mayor índice de impacto del año 2012 (JCR), del área temática “Sport Science” y los 10 artículos con mayor número de citas de las 10 revistas relacionadas con las ciencias del deporte, con mayor índice de impacto del año 2012 (JCR), del Área “Hospitality Leisure Sport Tourism”. Los resultados más significativos señalaron que: a) el número medio de autores en las revistas del área temática “Sport Science”, está entre 3-4 autores, mientas que en las revistas relacionadas con las ciencias del deporte del Área “Hospitality Leisure Sport Tourism”, se sitúa entre 2-3 autores. Estos datos pueden servir de referencia tanto a evaluadores como a evaluados en sus diferentes criterios

Evaluation of the potential of total proanthocyanidin content in feces as an intake biomarker.

Due to the health benefits associated with proanthocyanidins (PAs), it is useful to identify dietary PA biomarkers that can be determined by simple methods. Since increased levels of circulating PA metabolites are associated with increased fecal PA content, this study explores the spectrophotometric measurement of fecal PA content and its use as a biomarker of PA intake. To this end, fecal PA content was measured using an adaptation of Porter’s spectrophotometric method in samples from a preclinical study and an observational study. In the former, excretion of 250–400 mg PA polymer equivalents/100 g feces was observed during supplementation and the day after, together with a significant association (p < 0.05) between PA intake and the excretion of both intact PAs and some PA metabolites, i.e., (+)-catechin, (−)-epicatechin and syringic acid. No relationship between intake and excretion was found in the observational study, either for the entire group (mean excretion of 240 ± 226 mg PA polymer equivalents/100 g feces) or after stratification into tertiles of consumption. In conclusion, the spectrophotometric determination of total PA content in feces proved to be a valid compliance marker in a preclinical study, but it was not associated with PA intake in free-living subjects. The potential of total PA excretion in observational studies, determined in fecal samples collected the day before dietary recall or in several fecal samples from the same subject, remains to be elucidated, as does a complete validation of the method proposed here.post-print552 K

Time evolution of in vivo articular cartilage repair induced by bone marrow stimulation and scaffold implantation in rabbits

Purpose: Tissue engineering techniques were used to study cartilage repair over a 12-month period in a rabbit model. Methods: A full-depth chondral defect along with subchondral bone injury were originated in the knee joint, where a biostable porous scaffold was implanted, synthesized of poly(ethyl acrylate-co-hydroxyethyl acrylate) copolymer. Morphological evolution of cartilage repair was studied 1 and 2 weeks, and 1, 3, and 12 months after implantation by histological techniques. The 3-month group was chosen to compare cartilage repair to an additional group where scaffolds were preseeded with allogeneic chondrocytes before implantation, and also to controls, who underwent the same surgery procedure, with no scaffold implantation. Results: Neotissue growth was first observed in the deepest scaffold pores 1 week after implantation, which spread thereafter; 3 months later scaffold pores were filled mostly with cartilaginous tissue in superficial and middle zones, and with bone tissue adjacent to subchondral bone. Simultaneously, native chondrocytes at the edges of the defect started to proliferate 1 week after implantation; within a month those edges had grown centripetally and seemed to embed the scaffold, and after 3 months, hyaline-like cartilage was observed on the condylar surface. Preseeded scaffolds slightly improved tissue growth, although the quality of repair tissue was similar to non-preseeded scaffolds. Controls showed that fibrous cartilage was mainly filling the repair area 3 months after surgery. In the 12-month group, articular cartilage resembled the untreated surface. Conclusions: Scaffolds guided cartilaginous tissue growth in vivo, suggesting their importance in stress transmission to the cells for cartilage repair.This study was supported by the Spanish Ministry of Science and Innovation through MAT2010-21611-C03-00 project (including the FEDER financial support), by Conselleria de Educacion (Generalitat Valenciana, Spain) PROMETEO/2011/084 grant, and by CIBER-BBN en Bioingenieria, Biomateriales y Nanomedicina. The work of JLGR was partially supported by funds from the Generalitat Valenciana, ACOMP/2012/075 project. CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the - Instituto de Salud Carlos III with assistance from the European Regional Development Fund.Sancho-Tello Valls, M.; Forriol, F.; Gastaldi, P.; Ruiz Sauri, A.; Martín De Llano, JJ.; Novella-Maestre, E.; Antolinos Turpín, CM.... (2015). 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Combining self-assembling peptide gels with three-dimensional elastomer scaffolds

[EN] Some of the problems raised by the combination of porous scaffolds and self-assembling peptide (SAP) gels as constructs for tissue engineering applications are addressed for the first time. Scaffolds of poly(- ethyl acrylate) and the SAP gel RAD16-I were employed. The in situ gelation of the SAP gel inside the pores of the scaffolds was studied. The scaffold-cum-gel constructs were characterized morphologically, physicochemically and mechanically. The possibility of incorporating an active molecule (bovine serum albumin, taken here as a model molecule for others) in the gel within the scaffold’s pores was assessed, and the kinetics of its release in phosphate-buffered saline was followed. Cell seeding and colonization of these constructs were preliminarily studied with L929 fibroblasts and subsequently checked with sheep adipose-tissue-derived stem cells intended for further preclinical studies. Static (conventional) and dynamically assisted seedings were compared for bare scaffolds and the scaffold-cum-gel constructs. The SAP gel inside the pores of the scaffold significantly improved the uniformity and density of cell colonization of the three-dimensional (3-D) structure. These constructs could be of use in different advanced tissue engineering applications, where, apart from a cell-friendly extracellular matrix -like aqueous environment, a larger-scale 3-D structure able to keep the cells in a specific place, give mechanical support and/or conduct spatially the tissue growth could be required.The authors acknowledge funding through the European Commission FP7 project RECATABI (NMP3-SL-2009-229239), and from the Spanish Ministerio de Ciencia e Innovacion through projects MAT2011-28791-C03-02 and -03. Dr. J.C. Chachques (Hopital Europeen Georges Pompidou, Paris) is thanked for providing the ASCs employed in this study. MMP acknowledges support of CIBER-BBN initiative, financed by Institut de Salud Carlos III (Spain) with the assistance of the European Regional Development Fund.Vallés Lluch, A.; Arnal Pastor, MP.; Martínez Ramos, C.; Vilariño Feltrer, G.; Vikingsson, L.; Castells Sala, C.; Semino, CE.... (2013). Combining self-assembling peptide gels with three-dimensional elastomer scaffolds. Acta Biomaterialia. 9(12):9451-9460. https://doi.org/10.1016/j.actbio.2013.07.038S9451946091

Reference values in the number of authors in the best publications of scientifc journals in the area of physical activity and sport sciences

El propósito del presente estudio es analizar el número de autores de los principales artículos relacionados con las ciencias de la actividad física y del deporte de la Web of Science. Para ello se analizaron los 10 artículos con mayor número de citas de las 10 revistas con mayor índice de impacto del año 2012 (JCR), del área temática “Sport Science” y los 10 artículos con mayor número de citas de las 10 revistas relacionadas con las ciencias del deporte, con mayor índice de impacto del año 2012 (JCR), del Área “Hospitality Leisure Sport Tourism”. Los resultados más signifcativos señalaron que: a) el número medio de autores en las revistas del área temática “Sport Science”, está entre 3-4 autores, mientas que en las revistas relacionadas con las ciencias del deporte del Área “Hospitality Leisure Sport Tourism”, se sitúa entre 2-3 autores. Estos datos pueden servir de referencia tanto a evaluadores como a evaluados en sus diferentes criterios.Abstract: Te purpose of this study is to analyze the number of authors of the articles in the sciences of physical activity and sport in the Web of Science. Ten artices with more citations of the 10 journals with the highest impact factor in 2012 (JCR), the thematic area «Sport Science» and the 10 articles with more citations of the 10 related journals were analyzed sports science, with highest impact in 2012 (JCR) of area «Hospitality Leisure sport Tourism». Te most signifcant results indicated that: a) the average number of authors in the journals of the subject area «Sport Science», is 3-4 authors, while in the related sports science journals Area «Hospitality Leisure Sport Tourism «is between 2-3 authors. Tese data may serve as reference both evaluators as assessed in diferent criteria

Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition