Citizens contributing in landscape in the Netherlands

With the continuing loss of landscape elements and open space, landscape management is gaining importance in tandem with the design of acceptable private and voluntary financing arrangements. Here, we analyze the awareness, involvement, socio-demographic characteristics and the contribution of citizens regarding the landscape. The contribution of citizens has been classified into three fields of activities. Data analysis is based on a survey among 1.060 inhabitants in and around three designated peri-urban areas in the Netherlands. The results show that these areas are well known, albeit on a limited scale. Most of the stated willingness of the inhabitants to contribute to the landscape has been related with their socio-demographic characteristics and to a less extent with their involvement with the landscape. To increase the willingness of citizens to contribute to the landscape the communication strategy may be improved

Exotic Rickettsiae in Ixodes ricinus: fact or artifact?

Several pathogenic Rickettsia species can be transmitted via Ixodes ricinus ticks to humans and animals. Surveys of I. ricinus for the presence of Rickettsiae using part of its 16S rRNA gene yield a plethora of new and different Rickettsia sequences. Interpreting these data is sometimes difficult and presenting these findings as new or potentially pathogenic Rickettsiae should be done with caution: a recent report suggested presence of a known human pathogen, R. australis, in questing I. ricinus ticks in Europe. A refined analysis of these results revealed that R. helvetica was most likely to be misinterpreted as R. australis. Evidence in the literature is accumulating that rickettsial DNA sequences found in tick lysates can also be derived from other sources than viable, pathogenic Rickettsiae. For example, from endosymbionts, environmental contamination or even horizontal gene transfer

Social goals and gains of adolescent bullying and aggression:A meta-analysis

There is a long-standing debate on the goals that underlie adolescent socially coercive behaviors, such as bullying, relational aggression, and instrumental aggression. Knowledge about these goals is critical for the development of effective interventions. Bridging evolutionary and social-cognitive perspectives, we propose and substantiate a Social Goals and Gains Model of Adolescent Bullying and Aggression. The model holds that adolescents who hold agentic goals (i.e., getting ahead of others), rather than communal goals (i.e., getting along with others), engage in more bullying and aggression. Engaging in bullying and aggression, in turn, may lead adolescents to gain popularity but lose likeability. To substantiate this model, we meta-analyzed data of 164,143 adolescents (age range: 8–20 years), from 148 independent samples, with Meta-Analytic Structural Equation Modeling (MASEM). Our results both support and refine our model. As hypothesized, adolescents’ agentic goals were associated with higher levels of bullying and aggression. Bullying and aggression, in turn, were associated with higher popularity but lower likeability. However, there was no significant association between adolescents’ communal goals and bullying or aggression. These findings suggest that socially coercive behaviors, such as bullying and aggression, can be fueled by agentic goals and potentially lead to gains in popularity but losses in likeability. This suggests that intervention programs could reduce bullying and aggression by changing the means through which adolescents pursue agentic goals.</p

Brand and generic use of inhalation medication and frequency of switching in children and adults : a population-based cohort study

BACKGROUND: The expiration of patents of brand inhalation medications and the ongoing pressure on healthcare budgets resulted in a growing market for generics. AIM: To study the use of brand and generic inhalation medication and the frequency of switching between brand and generic and between devices. In addition, we investigated whether switching affected adherence. METHODS: From dispensing data from the Dutch PHARMO Database Network a cohort aged ≥ 5 years, using ≥ 1 year of inhalation medication between 2003 and 2012 was selected. Switching was defined as changing from brand to generic or vice versa. In addition, we studied change in aerosol delivery device type (e.g., DPI, pMDI, and nebulizers). Adherence was calculated using the medication possession ratio (MPR). RESULTS: The total cohort comprised 70,053 patients with 1,604,488 dispensations. Per calendar year, 5% switched between brand and generic inhalation medication and 5% switched between devices. Median MPRs over the first 12 months ranged between 33 and 55%. Median MPR over the total period was lower after switch from brand to generic and vice versa for formoterol (44.5 vs. 42.1 and 63.5 vs. 53.8) and beclomethasone (93.8 vs. 59.8 and 81.3 vs. 55.9). CONCLUSION: Per year, switching between brand and generic inhalation medication was limited to 5% of the patients, switching between device types was observed in 5% as well. Adherence to both generic and brand inhalation medication was low. Effect of switching on adherence was contradictory; depending on time period, medication and type, and direction of switching. Further research on reasons for switching and potential impact on clinical outcomes is warranted