Operational leeway in the work situations: Do ergonomic risk assessment tools consider operational leeway for job analysis?

Our study shows that information on operational leeway is limited in the originator articles of the ergonomic risk assessment tools for prevention of musculoskeletal disorders (MSDs). The tools\u27 underlying theoretical models do not consider the indicators of operational leeway, and they cannot determine the sufficiency of the situational operational leeway in a work situation. Consequently, regulation of the activity, which ensures the performance goals and the individual\u27s health, has been overlooked. The lack of literature on the indicators of situational operational leeway is one of the reasons for this deficit. Defining the indicators for this concept would be an innovation in the approach of MSDs risk prevention. Developing empirically the concept of situational operational leeway in the risk assessment tools would help to progress in the current approach of MSDs prevention. This study therefore proposes the indicators of the situational operational leeway to increase the representativeness and reliability of the risk assessment tools for MSDs

Antitumour responses induced by short-term pretreatment with tumour cells.

The injection (s.c. or i.p.) of 10(6) live or lethally irradiated methylcholanthrene-induced fibrosarcoma cells into CBA/Ca mice one or 2 days before i.v. challenge with the same tumour inhibited the formation of artificial lung tumour metastases. In addition, it also frequently enhanced the cytostatic effect of peritoneal exudate cells on monolayers of the same tumour. The effects on lung tumour metastasis were not noted if X-irradiated tumour was injected i.v., or if s.c. administration was delayed until one day after i.v. challenge. Similar effects on tumour growth were also observed in C3Hf/Bu mice and (CBA/Ca x A/HeJ) F1 hybrids which were pretreated (s.c.) with tumour shortly before i.v. challenge with the same tumour. Further studies in CBA/Ca mice suggested that the protective effect was tumour-specific, for the growth of i.v. injected tumour was not significantly inhibited by pretreatement with a number of other MC-induced or spontaneous tumours from the same and different strains

The influence of HIV infection on the age dependence of squamous cell carcinoma of the skin in South Africa

BACKGROUND. Cancer incidence typically increases with age, but it is not known whether ethnic characteristics influence the age dependence of squamous cell carcinoma of the skin (SCC). OBJECTIVES. (i) To determine the age dependence of SCC in the black African, coloured and white population groups of South Africa (SA); and (ii) to show whether any differences in the rate of change of age dependence could be influenced by diversity in behaviour and lifestyle, especially with regard to the prevalence of HIV infection, rather than by a fundamental variation in cancer biology between the populations. METHODS. Linear regression analysis was applied to the logarithm of the age-specific incidence rates for SCC v. the logarithm of age between 35 and 74 years. The slopes of the regression (age exponent) were compared for each subset of gender, population group and year of diagnosis (between 2000 and 2010). RESULTS. The most notable feature was the low value of the age exponent in both male and female black African compared with the white and coloured populations. This finding could be explained in part by the difference in the prevalence of HIV infection in the black African population group compared with the white and coloured population groups. CONCLUSIONS. The prevalence of HIV infection in black Africans in SA tends to decrease the apparent age component in SCC compared with the white and coloured population groups. Other factors relating to lifestyle and behaviour that differ between the population groups are also likely to influence the age component in SCC.The National Research Foundation of South Africa and the South African Medical Research Council.http://www.samj.org.zaam2017Geography, Geoinformatics and Meteorolog

Genomic plasticity and rapid host switching can promote the evolution of generalism : a case study in the zoonotic pathogen Campylobacter

This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) grant BB/I02464X/1, the Medical Research Council (MRC) grants MR/M501608/1 and MR/L015080/1, and the Wellcome Trust grant 088786/C/09/Z. GM was supported by a NISCHR Health Research Fellowship (HF-14–13).Peer reviewedPublisher PD

Pulsed beams as field probes for precision measurement

We describe a technique for mapping the spatial variation of static electric, static magnetic, and rf magnetic fields using a pulsed atomic or molecular beam. The method is demonstrated using a beam designed to measure the electric dipole moment of the electron. We present maps of the interaction region, showing sensitivity to (i) electric field variation of 1.5 V/cm at 3.3 kV/cm with a spatial resolution of 15 mm; (ii) magnetic field variation of 5 nT with 25 mm resolution; (iii) radio-frequency magnetic field amplitude with 15 mm resolution. This new diagnostic technique is very powerful in the context of high-precision atomic and molecular physics experiments, where pulsed beams have not hitherto found widespread application.Comment: 6 pages, 12 figures. Figures heavily compressed to comply with arxiv's antediluvian file-size polic

Ecological studies on Ixodes (Afrixodes) matopi Spickett, Keirans, Norval & Clifford, 1980 (Acarina: Ixodidae)

Ixodes (Afrixodes) matopi occurs in association with the klipspringer (Oreotragus oreotragus) in rocky areas in Zimbabwe. The adult ticks are specific parasites of this antelope and the immature stages feed on klipspringers, hyraxes (Procavia capensis and Heterohyrax brucei) and red rock hares (Pronolagus crassicaudatus). Adults are active only in the wet season and prior to feeding are found on bushes growing adjacent to rocks. The ticks aggregate on twigs which have been marked with the secretions of the pre-orbital glands of klipspringers. Larvae are evident in greatest numbers in the latter part of the wet season and nymphs in the cool dry season. Unfed larvae and nymphs occur predominantly on mats of humid leaf litter in the cracks and gaps between rocks, and both show well defined patterns of daily activity.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

Solar ultraviolet radiation in Africa : a systematic review and critical evaluation of the health risks and use of photoprotection

Most information on the harmful health effects of solar ultraviolet radiation (UVR) has been obtained in populations in which the majority has fair skin. Here a systematic review of evidence on diseases related to solar UVR in Africa was undertaken, and the appropriateness of effective photoprotection for these people considered. There are few population-based studies on UV-induced skin cancers (melanoma, squamous and basal cell carcinomas) in Africa, although limited reports indicated that they occur, even in people with deeply pigmented skin. The incidence of melanoma is particularly high in the white population living in the Western Cape of South Africa and has increased significantly in recent years. Cataract is extremely common in people of all skin colours and is a frequent cause of blindness, particularly in the elderly. For both skin cancer and cataract, the proportion of the disease risk that is attributable to exposure to solar UVR in African populations, and therefore the health burden caused by UV irradiation is unclear. There was little published information on the use of sun protection in Africa. The potential disease burden attributable to solar UVR exposure of Africans is high, although accurate data to quantify this are sparse. Information is required on the incidence, prevalence and mortality for the range of UVrelated diseases in different populations living throughout Africa. Photoprotection is clearly required, at least for those subpopulations at particularly high risk, but may be limited by cost and cultural acceptability.www.rsc.org/ppsam2016Geography, Geoinformatics and Meteorolog