EFFECT OF WELDING PROCESS PARAMETERS ON TENSILE OF LOW CARBON STEEL 283 G.C

In this study, three welding methods are used. The purpose to investigation the effects of SMAW, SAW, and gas tungsten arc welding (GTAW) on the tensile stress of low carbon steel conforming to ASTM 283 c. 8mm thick plates are used as base material for butt welded joints. The tensile properties of the welded joints were evaluated and the results were compared by experts using the Taguchi method to design three levels of each parameter (current, voltage and displacement speed). From this research, it is found that compared to metal shielded arc welding and submerged arc welding, the pulling effect of the gas shielded welding joint of the tungsten electrode is the best. This is mainly due to the presence of The results of using analysis of variance (ANOVA) to estimate important parameters show that welding current and speed of the weld have a significant effect on tensile stress. The experimental results are in agreement with predicted results, and the maximum error is 3%

SLANTLET TRANSFORM-BASED OFDM SCHEME

Wireless digital communication is rapidly expanding resulting in a demand for systems that are reliable and have a high spectral efficiency. To fulfill these demands OFDM technology has drawn a lot of attention. In this paper a new technique is proposed to improve the performance of OFDM. The new technique is use the slantlet transform (SLT) instead Fast Fourier transform (FFT) in order to reduce the level of interference. This also will remove the need for Guard interval (GI) in the case of the FFT-OFDM and therefore improve the bandwidth efficiency of the OFDM. The SLT-OFDM is also better than wavelet packet (WP)-OFDM in the selective channel because the slantlet filter bank is less frequency selective than the traditional DWT filter bank, due to the shorter length of the filters and SLT algorithm is faster than WP algorithm. The main results obtained indicate that the performance of SLT-OFDM is better on average by 18dB in comparison with that of FFT-OFDM flat fading channels. For frequency selective fading channel the SLT-OFDM performs is better than the FFT-OFDM on the lower SNR region, while the situation will reverse with increase SNR values

C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis

It is important to understand how the disease process affects the metabolic pathways in amyotrophic lateral sclerosis and whether these pathways can be manipulated to ameliorate disease progression. To analyse the basis of the metabolic defect in amyotrophic lateral sclerosis we used a phenotypic metabolic profiling approach. Using fibroblasts and reprogrammed induced astrocytes from C9orf72 and sporadic amyotrophic lateral sclerosis cases we measured the production rate of reduced nicotinamide adenine dinucleotides (NADH) from 91 potential energy substrates simultaneously. Our screening approach identified that C9orf72 and sporadic amyotrophic lateral sclerosis induced astrocytes have distinct metabolic profiles compared to controls and displayed a loss of metabolic flexibility that was not observed in fibroblast models. This loss of metabolic flexibility, involving defects in adenosine, fructose and glycogen metabolism, as well as disruptions in the membrane transport of mitochondrial specific energy substrates, contributed to increased starvation induced toxicity in C9orf72 induced astrocytes. A reduction in glycogen metabolism was attributed to loss of glycogen phosphorylase and phosphoglucomutase at the protein level in both C9orf72 induced astrocytes and induced neurons. In addition, we found alterations in the levels of fructose metabolism enzymes and a reduction in the methylglyoxal removal enzyme GLO1 in both C9orf72 and sporadic models of disease. Our data show that metabolic flexibility is important in the CNS in times of bioenergetic stress

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Molecular Detection and Associated Risk Factors of <i>Brucella melitensis</i> in Aborted Sheep and Goats in Duhok Province, Iraq

Brucellosis in sheep and goats has a significant economic and zoonotic impact on the livestock population of Duhok province, Iraq. A total of 681 blood samples from aborted sheep and goats were collected from different flocks in seven districts of Duhok and tested using real-time polymerase chain reaction (RT-PCR). Logistic regression was used for the analysis of the potential risk factors associated with RT-PCR positivity. Results revealed an overall prevalence of 35.45% (CI = 2.57) and 23.8% 18 (CI = 0.44) in sheep and goats, respectively. A statistically significant (p = 0.004) difference in prevalence was found between the two species. RT-PCR detected more positive cases in older-aged animals (OR = 0.7164; p = 0.073). A significant difference was found in RT-PCR positivity in relation to different risk factors, including body condition, treatment taken, and abortion frequency (B. melitensis and shared a common ancestor and were genetically related to the United States of America (USA), Greece, China, and Nigeria. This study demonstrates that brucellosis is widely prevalent in the study regions. Therefore, the study suggests the implementation of preventive control measures for brucellosis

The Influence of Irrigation with Different Solutions on Apical Microleakage of Root Canals

Aims: This study aims to assess the apical microleakage of root canals after irrigation by NaOCl, EDTA, and MTAD. Materials and methods: 36 lower premolars were used in this study. Preparation of the samples was done by files of ProTaper to size F3. Samples were distributed into three experimenting groups; each one contained ten samples as follows: Group 1- samples were finally washed for five minutes with five ml of 5.25% NaOCl. Group 2- samples were finally washed for five minutes with five ml of 17% EDTA. Group 3- samples were finally washed for five minutes with five ml of MTAD. Six samples were utilized as positive and negative control groups, each one contained three samples. The samples were obturated by single cone technique except for the samples of the positive control group, which were not obturated. All the samples were incubated at 37 OC for 7 days in 100% humidity. The dye penetration method was used to assess apical leakage. Finally, data was collected and statistically analyzed. Results: MTAD group revealed the least leakage supervened by the EDTA group and the NaOCl group revealed the highest leakage. The MTAD group did not differ significantly from the EDTA group, while the NaOCl group differed significantly from MTAD and EDTA groups. A group of positive control revealed a dye leak through the whole length of the root, while a group of negative control did not reveal any dye leak. Conclusions: Under the conditions of this study, the final irrigation with MTAD or EDTA is better than the final irrigation with 5.25 % NaOCl in terms of less apical microleakage

An adaptive scalable multiuser-OFDM system for multimedia transmission over fading channels

In this paper, an adaptive scalable multiuser-OFDM system was proposed for multimedia transmission over fading channels. The proposed adaptive algorithm can adapt according to the channel status information of each user\u27s channel status. This algorithm dynamically changes according to the user\u27s channel changes; this can keep fixed QoS at the physical layer. Another predefined QoS for different sessions and services to be provided for different users. This QoS can be guaranteed by multimedia scalability. Scalability can adapt to the service requirements, in terms of transmission data rate and bandwidth. As a result, a robust multimedia transmission scheme is achieved by providing fix QoS for the end users in multiuser environment, by fixing QoS in the physical layer by the bit and power adaptation technique and also in service layer by scalability techniques. Furthermore, space diversity techniques are used to decrease the effect of frequency selective multipath effects in broadband wireless channels