1,998 research outputs found

    The Relationship of Streptococcus Fecalis to Psoriasis

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    MINT (STEM) MENTORING IN BAVARIA: TESTING A FUNCTIONAL MODEL OF MENTORING

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    This research project develops an understanding of the MINT (STEM) mentoring programs geared to – and currently offered to – female students at Bavarian Universities of Applied Sciences. Using survey responses from mentors, mentees, and program managers, a functional model of mentoring was tested, exploring the understanding and support – or lacking support - of these MINT mentoring programs in their organizational and societal context were explored. Furthermore, the matching process, the perceived factors that might contribute to success of mentoring, and the development and growth of individuals in the mentor-mentee relationship and the organization overall, were assessed. Lastly, the perceived need for female mentors in these mentoring programs were examined. Development and growth of the mentors and the organization’s programs are perceived, but the same does not hold true for the mentees. Recommendations to enhance the program and to augment mentee growth and development are explored

    Peran Kategori Produk Sebagai Pemoderasi Citra Negara Asal Pada Ekuitas Merek

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    Brand is very important for marketers as the identity for the product to be marketed in order to be distinguished from other products. Moreover, the current competition for the market not only occur between companies locally or nationally but already global as well. Country of origin is often listed together with the provision that the brand is expected to improve the equity of the brand. However, information about the country of origin is not always going to be able to increase brand equity. Still happens practically and theoretically gab about the influence of the country of origin on brand equity. Specify the country of origin was able to reduce the brand equity. The absence of studies to determine whether or not to inform the country of origin, especially for Indonesian products in order to compete in the era of globalization makes this study important. This research was conducted in order to determine consumer preference for a particular brand of product categories are associated strongly with the state of Indonesia (batik) and and is not associated strongly with Indonesia (lap top). So it can be used as a reference for marketers Indonesia to determine whether or not to inform important country of origin for their products. Research will be carried out by a questionnaire survey as a data collector. The sampling technique used purposive sampling by taking 150x2 respondents. Analysis of data to determine the moderating role of product categories on the influence of the image of the country of origin of brand equity to do with the sub-group analysis using the chow test

    Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire

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    BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used for mass drug administration programs for lymphatic filariasis (LF) outside of sub-Saharan Africa. Triple-drug therapy has not been previously tested in LF-uninfected individuals from Africa. This study evaluated the pharmacokinetics (PK), safety, and efficacy of triple-drug therapy in people with and without Wuchereria bancrofti infection in West Africa.MethodsIn this open-label cohort study, treatment-naïve microfilaremic (>50 mf/mL, n = 32) and uninfected (circulating filarial antigen negative, n = 24) adults residing in Agboville district, Côte d’Ivoire, were treated with a single dose of IVM plus DEC plus ALB, and evaluated for adverse events (AEs) until 7 days post treatment. Drug levels were assessed by liquid chromatography and mass spectrometry. Persons responsible for assessing AEs were blinded to participants’ infection status.FindingsThere was no difference in AUC0-inf or Cmax between LF-infected and uninfected participants (P>0.05 for all comparisons). All subjects experienced mild AEs; 28% and 25% of infected and uninfected participants experienced grade 2 AEs, respectively. There were no severe or serious adverse events. Only fever (16 of 32 versus 4 of 24, PConclusionsModerate to heavy W. bancrofti infection did not affect PK parameters for IVM, DEC or ALB following a single co-administered dose of these drugs compared to uninfected individuals. The drugs were well tolerated. This study confirmed the efficacy of the triple-drug therapy for clearing W. bancrofti Mf and has added important information to support the use of this regimen in LF elimination programs in areas of Africa without co-endemic onchocerciasis or loiasis.Trial registrationClinicalTrials.gov NCT02845713.</div

    A Critical Examination of Contemporary Legal Issues Important to College Presidents

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    This discussion provides a highlight of the legal dimensions that college presidents must consider in providing oversight for college operations. Many of these issues are driven by the behaviors of campus constituents, but several key legal issues are also the result of federal legislation and involvement in higher education

    Instantaneous Normal Mode analysis of liquid HF

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    We present an Instantaneous Normal Modes analysis of liquid HF aimed to clarify the origin of peculiar dynamical properties which are supposed to stem from the arrangement of molecules in linear hydrogen-bonded network. The present study shows that this approach is an unique tool for the understanding of the spectral features revealed in the analysis of both single molecule and collective quantities. For the system under investigation we demonstrate the relevance of hydrogen-bonding ``stretching'' and fast librational motion in the interpretation of these features.Comment: REVTeX, 7 pages, 5 eps figures included. Minor changes in the text and in a figure. Accepted for publication in Phys. Rev. Let

    Stone-Wales Transformation Paths in Fullerene C60

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    The mechanisms of formation of a metastable defect isomer of fullerene C60 due to the Stone-Wales transformation are theoretically studied. It is demonstrated that the paths of the "dynamic" Stone-Wales transformation at a high sufficient for overcoming potential barriers) temperature can differ from the two "adiabatic" transformation paths discussed in the literature. This behavior is due to the presence of a great near-flat segment of the potential-energy surface in the neighborhood of metastable states. Besides, the sequence of rupture and formation of interatomic bonds is other than that in the case of the adiabatictransformation.Comment: 10 pages, 6 figure

    Compiling a Comprehensive EVA Training Dataset for NASA Astronauts

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    Training for a spacewalk or extravehicular activity (EVA) is considered hazardous duty for NASA astronauts. This activity places astronauts at risk for decompression sickness as well as various musculoskeletal disorders from working in the spacesuit. As a result, the operational and research communities over the years have requested access to EVA training data to supplement their studies

    Instantaneous Normal Mode Analysis of Supercooled Water

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    We use the instantaneous normal mode approach to provide a description of the local curvature of the potential energy surface of a model for water. We focus on the region of the phase diagram in which the dynamics may be described by the mode-coupling theory. We find, surprisingly, that the diffusion constant depends mainly on the fraction of directions in configuration space connecting different local minima, supporting the conjecture that the dynamics are controlled by the geometric properties of configuration space. Furthermore, we find an unexpected relation between the number of basins accessed in equilibrium and the connectivity between them.Comment: 5 pages, 4 figure

    Lessons learnt, and still to learn, in first in human stem cell trials

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    Developing cellular therapies is not straightforward. This Perspective summarizes the experience of a group of academic stem cell investigators working in different clinical areas and aims to share insight into what we wished we knew before starting. These include (1) choosing the stem cell line and assessing the genome of both the starting and final product, (2) familiarity with GMP manufacturing, reagent validation, and supply chain management, (3) product delivery issues and the additional regulatory challenges, (4) the relationship between clinical trial design and preclinical studies, and (5) the market approval requirements, pathways, and partnerships needed
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