444 research outputs found

    Testing Optimization of Molecular Oncology Assays

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    Disordered Carbon nanotube alloys in the Effect Medium Super Cell Approximation

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    We investigate a disordered single-walled carbon nanotube (SWCNT) in an effective medium super cell approximation (EMSCA). First type of disorder that we consider is the presence of vacancies. Our results show that the vacancies induce some bound states on their neighbor host sites, leading to the creation of a band around the Fermi energy in the SWCNT average density of states.Second type of disorder considered is a substitutional BcbNcnC1cbcnB_{cb}N_{cn}C_{1-cb-cn} alloy due to it's applications in hetrojunctions. We found that for a fixed boron (nitrogen) concentration, by increasing the nitrogen (boron) concentration the averaged semiconducting gap, EgE_{g}, decreases and at a critical concentration it disappears. A consequence of our results for nano electronic devices is that by changing the boron(nitrogen) concentration, one can make a semiconductor SWCNT with a pre-determined energy gap.Comment: 4 page

    Diagnostic errors in echocardiography: Review of five interesting pediatric cases

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    Echocardiography is considered the primary diagnostic tool for congenital heart diseases. The pediatric echocardiography diagnostic errors, consisting of false positive or discrepant diagnoses, picked up within a 2.5-year period in our pediatric echocardiography laboratory are presented herein. In this case report, the factors contributing to the diagnostic errors are categorized as cognitive such as misidentification/misinterpretation of findings and distraction by other diagnoses; procedural or conditional such as incomplete examination of anatomy/physiology and poor imaging conditions; and finally communicational or informational such as lacking or misleading patient's history and incorrect requisition. The quality of diagnostic pediatric echocardiography can be improved if the operator has sufficient knowledge about the normal growth and development of children, different types of congenital heart defects, and principles of ultrasound physics

    Ferromagnetic semiconductor single wall carbon nanotube

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    Possibility of a ferromagnetic semiconductor single wall carbon nanotube (SWCNT), where ferromagnetism is due to coupling between doped magnetic impurity on a zigzag SWCNT and electrons spin, is investigate. We found, in the weak impurity-spin couplings, at low impurity concentrations the spin up electrons density of states remain semiconductor while the spin down electrons density of states shows a metallic behavior. By increasing impurity concentrations the semiconducting gap of spin up electrons in the density of states is closed, hence a semiconductor to metallic phase transition is take place. In contrast, for the case of strong coupling, spin up electrons density of states remain semiconductor and spin down electron has metallic behavior. Also by increasing impurity spin magnitude, the semiconducting gap of spin up electrons is increased.Comment: 10 pages and 9 figure

    The effect of thyroxine on percentage of hatching (Hypophthalmichthys molitrix)

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    Studies showed that Thyroxine can play an important role on fish growth, osmoregulation system, and other physiological activities. Since the direct effect of thyroxine on growth and metamorphose of bony fish larvae has not been yet approved, therefore, present study were carried out in Shahid Ansary propagation and cultivation farm in order to find out the way of effect of this hormone on the survirval rate and early growth stage of silver carp (Hypophthalmichthys molitrix) fertiled eggs that were bathed in thyroxin with concentrations of 0.1, 0.5 and 1.0 ppm (each one, replicates) for 6 hours. Then they were transfered into large incubators (zoog) with running water. After hatching all larvae were placed in mentioned thyroxin concentration bath for another 6 hours before being transfered into large incubators. Larvae stayed inzoogs until the yolk-sac was absorbed. Finally, live silver carp larvae were counted in separated plates. Results of present study indicated that the ra tio of hatched eggs in 0.5 ppm of thyroxin concentration was higher than other treatment

    Petrogenesis of the Lalezar granitoid intrusions (Kerman Province – Iran)

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    The Lalezar granitoids crop out within volcanic successions of the Urumieh-Dokhtar Magmatic Assemblage (UDMA). These granitoids have a range from gabbro-diorites to granites in composition. The mineral compositions of the most felsic rocks are characterized by the abundances of Na-plagioclase, quartz, alkali feldspar, biotite and hornblende. In the gabbro-diorite rocks, plagioclase (Ca-rich), hornblende, biotite and clinopyroxene are the most common minerals. Major element geochemical data show that the Lalezar granitoids are mostly metaluminous, although the most felsic members (granites) attain slightly peraluminous compositions and that they have features typical of high-K calc-alkaline rocks. In primitive mantle-normalized trace element spider diagrams, the analysed samples display strong enrichment in LILE compared to HFSE, accompanied by negative anomalies of Nb,Ta and Ti. REE chondrite-normalized plots show moderate LREE enrichment with slight to strong negative Eu anomalies. Rb–Sr geochronological data, mainly dependent on the Sr isotopic composition of biotite, was obtained in two samples and it points to 15-16 Ma. As a probable, age for the emplacement of the studied intrusives. Initial 87Sr/86Sr ratios and ƐNdi values range from 0.70495 to 0.70565 from +3.1 to +1.5 respectively, which fit into a supra-subduction mantle wedge source for the parental melts and indicates that, in general, crustal contribution for magma diversification was not relevant. Geochemical and isotopic evidence reveal that the Lalezar intrusions are cogenetic I-type granitoids which were generated in a continental arc setting, in agreement with models previously presented in the UDMA

    Intranasal administration of endometrial mesenchymal stem cells as a suitable approach for Parkinson�s disease therapy

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    This study aimed to investigate the therapeutic effects of intranasal administration of human endometrium-derived stem cells (HEDSCs) in the mouse model of Parkinson�s disease (PD). Thirty days after intrastriatal injection of 6-OHDA, HEDSCs were administrated intranasally in three doses (104, 5 � 104 and 105 cells µl�1). During 120 days after stem cell administration, behavioral tests were examined. Then the mice were sacrificed and the fresh section of the substantia nigra pars compacta (SNpc) was used for detection of HEDSCs-GFP labeled by fluorescence microscopy method. In addition, immunohistochemistry was used to assay GFP, human neural Nestin, and tyrosine hydroxylase (TH) markers in the fixed brain tissue at the SNpc. Our data revealed that behavioral parameters were significantly improved after cell therapy. Fluorescence microscopy assay in fresh tissue and GFP analysis in fixed tissue were showed that the HEDSCs-GFP labeled migrated to SNpc. The data from immunohistochemistry revealed that the Nestin as a differential neuronal biomarker was expressed in SNpc. Also, TH as a dopaminergic neuron marker significantly increased after HEDSCs therapy in an optimized dose 5 � 104 cells µl�1. Our results suggest that intranasal administration of HEDSCs improve the PD symptoms in the mouse model of PD dose-dependent manner as a noninvasive method. © 2019, Springer Nature B.V

    Effect of foot reflexology on anxiety and agitation in patients under mechanical ventilation after open heart surgery: A randomized clinical trial study

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    زمینه و هدف: رویکردهای غیر دارویی از جمله ماساژ بازتابی پا به علت کاهش عوارض و هزینه ها در کانون توجه محققین در جامعه بیماران مختلف قرار گرفته است. این مطالعه با هدف بررسی تأثیر ماساژ بازتابی پا بر اضطراب و بیقراری بیماران تحت تهویه مکانیکی پس از جراحی قلب باز انجام شد. روش بررسی: این مطالعه کارآزمایی بالینی کنترل شده، سه گروهی و دو سو کور با طراحی اندازه گیری مکرر در دو بیمارستان وابسته به دانشگاه علوم پزشکی بقیه الله (عج) تهران، از بهمن1392 تا اردیبهشت 1393 انجام شد. 96 بیمار کاندید جراحی قلب باز به روش نمونه گیری در دسترس انتخاب و به صورت تخصیص تصادفی در سه گروه آزمون (ماساژ بازتابی پا 34 نفر)، درمان نما (تماس سطحی پاشنه پا 30 نفر) و کنترل (مراقبت های معمول 32 نفر) قرار گرفتند. در گروه آزمون، ماساژ بازتابی پا به مدت20 دقیقه بر روی نقاط بازتاب قلب و ریه، انجام شد. میزان اضطراب و بیقراری بر اساس مقیاس سنجش اضطراب (FAS) و مقیاس سنجش بیقراری ریچموند (RSAS) در 6 مرحله زمانی ثبت شد. یافته ها: داده های آماری 92 بیمار (31 نفر گروه آزمون، 30 نفر گروه درمان نما و 31 نفر گروه کنترل) جمع آوری گردید. در مقایسه روند تغییرات سطح اضطراب و بیقراری، آزمون درون گروهی فریدمن نشان داد، بین میانگین سطح اضطراب و بیقراری در گروه ها در مراحل زمانی مختلف تفاوت معنی دار آماری وجود دارد. همچنین آزمون کروسکال والیس نشان داد میزان اضطراب و بیقراری بین سه گروه در مراحل مختلف زمانی تفاوت معنی دار آماری با یکدیگر ندارند. نتیجه گیری: ماساژ بازتابی پا در نقاط بازتابی مربوط به قلب و ریه تغییر معنی داری در کاهش اضطراب و بیقراری بیماران پس از جراحی ایجاد نکرد
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