Liquefaction of the Enmedio Island Soil Deposits

The results of field testing and of simplified liquefaction analyses of the Enmedio Island soil deposits are presented and discussed in this paper. It is found that for this case history simple criteria for assessing liquefaction potential yield results in accord with field behavior

Observed and Predicted Liquefaction of a Sand Stratum

Field observations and preliminary studies had led to the conclusion that the sand stratum liquefied only in a limited area during the March 14, 1979 earthquake. Further field studies revealed the presence of the sand layer throughout the Enmedio Island. This fact raised questions as to whether the sand liquefied or not in the whole area. To clarify this question, a research program which included cyclic triaxial testing and numerical analyses was undertaken. The results of this study show that the sand layer did liquefy through the Island; however, due to differences in stratigraphic characteristics, superficial signs of liquefaction were developed only in a restricted zone

Early Neoproterozoic limestones from the Gwna Group, Anglesey

Limestone megaclasts up to hundreds of metres in size are present within the Gwna Group mélange, North Wales, UK. The mélange has been interpreted as part of a Peri-Gondwanan fore-arc accretionary complex although the age of deposition remains contentious, proposals ranging from Neoproterozoic to Early Ordovician. This paper uses strontium isotope chemostratigraphy to establish the age of the limestone blocks and thus provide a maximum age constraint on mélange formation. Results show that, although the carbonates are locally dolomitized, primary 87Sr/86Sr ratios can be identified and indicate deposition sometime between the late Tonian and earliest Cryogenian. This age is older than that suggested by stromatolites within the limestone and indicates that the limestone did not form as cap carbonate deposits

Photovoltaic module segmentation and thermal analysis tool from thermal images

The growing interest in the use of clean energy has led to the construction of increasingly large photovoltaic systems. Consequently, monitoring the proper functioning of these systems has become a highly relevant issue.In this paper, automatic detection, and analysis of photovoltaic modules are proposed. To perform the analysis, a module identification step, based on a digital image processing algorithm, is first carried out. This algorithm consists of image enhancement (contrast enhancement, noise reduction, etc.), followed by segmentation of the photovoltaic module. Subsequently, a statistical analysis based on the temperature values of the segmented module is performed.Besides, a graphical user interface has been designed as a potential tool that provides relevant information of the photovoltaic modules.Comment: 7 pages, 12 Figure

EJERCICIOS DE CALENTAMIENTO COMO MEDIO PROFILÁCTICO EN LESIONES DE RODILLA EN FUTBOLISTAS./EXERCISES WARMING AS AVERAGE PROPHYLACTIC KNEE INJURIES IN FOOTBALL

Un aspecto fundamental a la hora de realizar la preparación de los jugadores y la más importante de cualquier etapa en un equipo, es sin duda el calentamiento. En este artículo, el cual tiene como objetivo fundamental actualizar y concientizar sobre la importancia de realizar un buen calentamiento, el cual puede hacer la diferencia entre un óptimo rendimiento del atleta y el no lesionarse. Para ello se realiza una revisión bibliográfica de distintos documentos que tratan sobre el tema a desarrollar.Palabras claves: Ejercicios, Profilácticos, Calentamiento AbstractA key aspect when making the preparation of the players and the most important stage of any team is undoubtedly warming. This article, which has as main objective to upgrade and raise awareness about the importance of a good warm up, which can make the difference between optimal athletic performance and avoid injury. To do a literature review of various documents dealing with the topic to be developed is done. Keywords: Exercises, Prophylactic, Heatin

Proteomics in drug hypersensitivity

21 p.-4 fig.-1 tab.Drug hypersensitivity reactions result from the activation of the immune system by drugs or their metabolites. The clinical presentations of drug hypersensitivity can range from relatively mild local manifestations to severe systemic syndromes that can be life-threatening. As in other allergic reactions, the causes are multifactorial as genetic, metabolic and concomitant factors may influence the occurrence of drug hypersensitivity. Formation of drug protein adducts is considered a key step in drug adverse reactions, and in particular in the immunological recognition in drug hypersensitivity reactions. Nevertheless, non-covalent interactions of drugs with receptors in immune cells or with MHC clefts and/or exposed peptides can also play an important role. In recent years, development of proteomic approaches has allowed the identification and characterization of the protein targets for modification by drugs in vivo and in vitro, the nature of peptides exposed on MHC molecules, the changes in protein levels induced by drug treatment, and the concomitant modifications induced by danger signals, thus providing insight into context factors. Nevertheless, given the complexity and multifactorial nature of drug hypersensitivity reactions, understanding the underlying mechanisms also requires the integration of knowledge from genomic, metabolomic and clinical studies.This work has been supported by grants SAF2012-36519 and SAF2015-68590R from MINECO/FEDER and RETIC RD12/0013/0008 from ISCIII to D.P.-S., and by RETIC RD12/0013/0001 and CP15/00103 from ISCIII, and PI-0699-2011 and PI-0179-2014 from Junta de Andalucía to M.I.M.Peer reviewe

Twofold topological phase transitions induced by third-nearest-neighbor interactions in 1D chains

Strong long-range interactions up to third nearest neighbors may induce a topological phase transition in one-dimensional chains. Unlike the Su-Schrieffer-Heeger model, this transition from trivial to topological phase occurs with the emergence of a pseudospin valley structure and a twofold nontrivial topological phase. Within a tight-binding approach, these topological phases are analyzed in detail and it is shown that the low-energy excitations follow a modified Dirac equation. An experimental realization in a one-dimensional elastic chain, where it is feasible to tune directly the third-nearest-neighbor interaction strength, is proposed.Comment: 6 pages, 3 figure

Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus

<p>Abstract</p> <p>Background</p> <p>Neuroinflammation occurs after seizures and is implicated in epileptogenesis. CCR2 is a chemokine receptor for CCL2 and their interaction mediates monocyte infiltration in the neuroinflammatory cascade triggered in different brain pathologies. In this work CCR2 and CCL2 expression were examined following status epilepticus (SE) induced by pilocarpine injection.</p> <p>Methods</p> <p>SE was induced by pilocarpine injection. Control rats were injected with saline instead of pilocarpine. Five days after SE, CCR2 staining in neurons and glial cells was examined using imunohistochemical analyses. The number of CCR2 positive cells was determined using stereology probes in the hippocampus. CCL2 expression in the hippocampus was examined by molecular assay.</p> <p>Results</p> <p>Increased CCR2 was observed in the hippocampus after SE. Seizures also resulted in alterations to the cell types expressing CCR2. Increased numbers of neurons that expressed CCR2 was observed following SE. Microglial cells were more closely apposed to the CCR2-labeled cells in SE rats. In addition, rats that experienced SE exhibited CCR2-labeling in populations of hypertrophied astrocytes, especially in CA1 and dentate gyrus. These CCR2+ astroctytes were not observed in control rats. Examination of CCL2 expression showed that it was elevated in the hippocampus following SE.</p> <p>Conclusion</p> <p>The data show that CCR2 and CCL2 are up-regulated in the hippocampus after pilocarpine-induced SE. Seizures also result in changes to CCR2 receptor expression in neurons and astrocytes. These changes might be involved in detrimental neuroplasticity and neuroinflammatory changes that occur following seizures.</p