459 research outputs found

    Slow equivariant lump dynamics on the two sphere

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    The low-energy, rotationally equivariant dynamics of n CP^1 lumps on S^2 is studied within the approximation of geodesic motion in the moduli space of static solutions. The volume and curvature properties of this moduli space are computed. By lifting the geodesic flow to the completion of an n-fold cover of the moduli space, a good understanding of nearly singular lump dynamics within this approximation is obtained.Comment: 12 pages, 3 figure

    Emissions budgets for shipping in a 2°C and a 4°C global warming scenario, and implications for operational efficiency

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    To achieve the widely accepted goal of keeping global temperature rise below 2°C above pre-industrial levels, greenhouse gas emissions must reduce drastically over the coming decades. Under this premise, the assumption that the shipping industry realises the same proportionate CO2 emission reductions as all other sectors on average has strong implications. This paper begins by considering an appropriate global CO2 emissions budget associated with a temperature rise of 2°C. Next, a range of future demand scenarios for international transport shipping are presented. Meeting the demand in any of the scenarios, while remaining within the emissions budget, requires stringent increases in overall operational efficiency. Different emissions and efficiency trajectories – with efficiency expressed in terms of the Energy Efficiency Operational Indicator (EEOI) – in line with the 2°C target are analysed. The potential short and long term levers of operational efficiency are explored

    Farmer Led Regenerative Agriculture for Africa

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    Magnetic bubble refraction and quasibreathers in inhomogeneous antiferromagnets

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    The dynamics of magnetic bubble solitons in a two-dimensional isotropic antiferromagnetic spin lattice is studied, in the case where the exchange integral J(x,y) is position dependent. In the near continuum regime, this system is described by the relativistic O(3) sigma model on a spacetime with a spatially inhomogeneous metric, determined by J. The geodesic approximation is used to describe low energy soliton dynamics in this system: n-soliton motion is approximated by geodesic motion in the moduli space of static n-solitons, equipped with the L^2 metric. Explicit formulae for this metric for various natural choices of J(x,y) are obtained. From these it is shown that single soliton trajectories experience refraction, with 1/J analogous to the refractive index, and that this refraction effect allows the construction of simple bubble lenses and bubble guides. The case where J has a disk inhomogeneity (taking the value J_1 outside a disk, and J_2<J_1 inside) is considered in detail. It is argued that, for sufficiently large J_1/J_2 this type of antiferromagnet supports approximate quasibreathers: two or more coincident bubbles confined within the disk which spin internally while their shape undergoes periodic oscillations with a generically incommensurate period.Comment: Conference proceedings paper for talk given at Nonlinear Physics Theory and Experiment IV, Gallipoli, Italy, June 200

    Quantum lump dynamics on the two-sphere

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    It is well known that the low-energy classical dynamics of solitons of Bogomol'nyi type is well approximated by geodesic motion in M_n, the moduli space of static n-solitons. There is an obvious quantization of this dynamics wherein the wavefunction evolves according to the Hamiltonian H_0 equal to (half) the Laplacian on M_n. Born-Oppenheimer reduction of analogous mechanical systems suggests, however, that this simple Hamiltonian should receive corrections including k, the scalar curvature of M_n, and C, the n-soliton Casimir energy, which are usually difficult to compute, and whose effect on the energy spectrum is unknown. This paper analyzes the spectra of H_0 and two corrections to it suggested by work of Moss and Shiiki, namely H_1=H_0+k/4 and H_2=H_1+C, in the simple but nontrivial case of a single CP^1 lump moving on the two-sphere. Here M_1=TSO(3), a noncompact kaehler 6-manifold invariant under an SO(3)xSO(3) action, whose geometry is well understood. The symmetry gives rise to two conserved angular momenta, spin and isospin. A hidden isometry of M_1 is found which implies that all three energy spectra are symmetric under spin-isospin interchange. The Casimir energy is found exactly on the zero section of TSO(3), and approximated numerically on the rest of M_1. The lowest 19 eigenvalues of H_i are found for i=0,1,2, and their spin-isospin and parity compared. The curvature corrections in H_1 lead to a qualitatively unchanged low-level spectrum while the Casimir energy in H_2 leads to significant changes. The scaling behaviour of the spectra under changes in the radii of the domain and target spheres is analyzed, and it is found that the disparity between the spectra of H_1 and H_2 is reduced when the target sphere is made smaller.Comment: 35 pages, 3 figure

    CO2 abatement goals for international shipping

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    The Paris Agreement, which entered into force in 2016, sets the ambitious climate change mitigation goal of limiting the global temperature increase to below 2°C and ideally 1.5°C. This puts a severe constraint on the remaining global GHG emissions budget. While international shipping is also a contributor to anthropogenic GHG emissions, and CO2 in particular, it is not included in the Paris Agreement. This article discusses how a share of a global CO2 budget over the twenty-first century could be apportioned to international shipping, and, using a range of future trade scenarios, explores the requisite cuts to the CO2 intensity of shipping. The results demonstrate that, under a wide range of assumptions, existing short-term levers of efficiency must be urgently exploited to achieve mitigation commensurate with that required from the rest of the economy, with virtually full decarbonization of international shipping required as early as before mid-century

    El territoi d'Emporion i les seves dades paleoambientals

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    Se aportan nuevos datos que provienen de un sondeo efectuado en las marismas del Arnpurdån (Girona). En resumen, la época ibérica se caracteriza por un aprovechamiento sostenibie de los recursos naturales y ia romana por potenciar mås ei cultivo de/ oiivo que el de los cereales; ia triada cereai/oiivo/viña es mås típica de los períodos medievales y posteriores. Predomina en ia zona un paisaje de ralos aicornocaies y encinares mixtos, con pocos pinos, determinado por un clima mediterråneo templado con escasas precipitaciones.New data are presented frorn a core takan frorn the wetiands of the Emporda (Girona). in summary, the iberian period is characterised by sustainable use of natural resources, whiie the Roman period shows more intensive cuitivation of olives than of cereals; the triad cereal/ olive/ vine is typicai of the medieval and iater periods. The predorninant landscape NI the area supported cork oak and other mixed species, with few pines, typical of a temperate Mediterranean ciirnate with iittle precipitation

    SLAP Is a Negative Regulator of FcΔRI Receptor-Mediated Signaling and Allergic Response

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    Binding of antigen to IgE-high affinity FcΔRI complexes on mast cells and basophils results in the release of preformed mediators such as histamine and de novo synthesis of cytokines causing allergic reactions. Src-like adapter protein (SLAP) functions co-operatively with c-Cbl to negatively regulate signaling downstream of the T cell receptor, B cell receptor, and receptor tyrosine kinases (RTK). Here, we investigated the role of SLAP in FcΔRI-mediated mast cell signaling, using bone marrow derived mast cells (BMMCs) from SLAP knock out (SLAP KO) mice. Mature SLAP-KO BMMCs displayed significantly enhanced antigen induced degranulation and synthesis of IL-6, TNFα, and MCP-1 compared to wild type (WT) BMMCs. In addition, SLAP KO mice displayed an enhanced passive cutaneous anaphylaxis response. In agreement with a negative regulatory role, SLAP KO BMMCs showed enhanced FcΔRI-mediated signaling to downstream effector kinases, Syk, Erk, and Akt. Recombinant GST-SLAP protein binds to the FcΔRIÎČ chain and to the Cbl-b in mast cell lysates, suggesting a role in FcΔRI down regulation. In addition, the ubiquitination of FcΔRIÎł chain and antigen mediated down regulation of FcΔRI is impaired in SLAP KO BMMCs compared to the wild type. In line with these findings, stimulation of peripheral blood human basophils with FcΔRIα antibody, or a clinically relevant allergen, resulted in increased SLAP expression. Together, these results indicate that SLAP is a dynamic regulator of IgE-FcΔRI signaling, limiting allergic responses

    Kinetics of plasma cell‐free DNA and creatine kinase in a canine model of tissue injury

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    Background: Cell‐free DNA (cfDNA) comprises short, double‐stranded circulating DNA sequences released from damaged cells. In people, cfDNA concentrations correlate well with disease severity and tissue damage. No reports are available regarding cfDNA kinetics in dogs. Objectives/Hypothesis: Cell‐free DNA will have a short biological half‐life and would be able to stratify mild, moderate, and severe tissue injury. Our study aims were to determine the kinetics and biological half‐life of cfDNA and to contrast them with those of creatine kinase (CK). Animals: Three groups of 10 dogs undergoing open ovariohysterectomy, surgery for cranial cruciate ligament rupture (CCLR), or hemilaminectomy. Methods: Plasma for cfDNA and CK analysis was collected at admission, at induction of anesthesia, postsurgery (time 0) and at 6, 12, 24, 36, 48, 60, and 72 hours after surgery. Results: The biological half‐life of plasma cfDNA and CK were 5.64 hours (95% confidence interval [CI 95], 4.36–7.98 hours) and 28.7 hours (CI95, 25.3–33.3 hours), respectively. In the hemilaminectomy group, cfDNA concentrations differed significantly from admission at 6–12 hours after surgery. Creatine kinase activity differed among the surgical groups and reached a peak 6 hours after surgery. In the ovariohysterectomy and CCLR groups, plasma CK activity 72 hours after surgery did not differ from admission activity of the ovariohysterectomy group. In contrast, in the hemilaminectomy group, plasma CK activity after 72 hours did not return to the ovariohysterectomy group admission activity. Conclusions and Clinical Importance: Plasma CK activity has a longer biological half‐life than previously thought. In contrast to plasma CK activity, cfDNA has a short half‐life and could be a useful marker for peracute severe tissue injury
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