Mitigating Suicide Risk Post-Discharge from Inpatient Crisis Stabilization: Safety Planning Intervention

Abstract Purpose: The purpose of this program evaluation is to evaluate the effectiveness of a newly implemented safety planning intervention (SPI) tool, comparing patient outcomes relating to suicide attempt rates, emergency department (ED) encounter rates, and inpatient rehospitalizations rates pre and post its integration to care in a suburban behavioral health hospital. Methods: A descriptive cohort design utilizing a retrospective chart review was completed over six months, three months pre, and three months post implementation of the SPI program. A convenience sample of inpatient charts was reviewed to assess the rate of suicide attempts, ED encounters frequencies, and hospitalization rates before and after the SPI program\u27s deployment. The context, input, process, and product (CIPP) model of evaluation was utilized. Results: A sample of 100 charts met study criteria. Sixty-four percent completed the SPI tool, 36% did not. There was a statistical reduction in the mean of emergency room encounters, inpatient admissions, suicide attempts, and post SPI implementation compared to pre (p \u3c .001). Suicidal ideation, when compared to post to pre SPI reduced as well (p = .013). Depressive disorder subjects (86%, n = 55) were most likely to complete the SPI while Malingerers were least likely to do so (0%, n = 0). Implications for Practice: This program evaluation appears to reveal the SPI tool\u27s positive impact on patient outcomes. With the most substantial change visualized in actual suicide attempts, the integration of the SPI in a suburban behavioral health inpatient setting may be a life-preserving tool

Low-speed aerodynamic characteristics of a 13-percent-thick airfoil section designed for general aviation applications

Wind-tunnel tests were conducted to determine the low-speed section characteristics of a 13 percent-thick airfoil designed for general aviation applications. The results were compared with NACA 12 percent-thick sections and with the 17 percent-thick NASA airfoil. The tests were conducted ovar a Mach number range from 0.10 to 0.35. Chord Reynolds numbers varied from about 2,000,000 to 9,000,000

The virtuous entrepreneur: new ventures and human flourishing

Entrepreneurship research in recent years has expanded to include the ethical dimension of new venture creation and various normative frameworks have been applied to the entrepreneurship role. Despite this, entrepreneurship is still widely viewed as a business phenomenon which bases its claim to be a key contributor to social good on economic grounds only. In this paper, the social good against which entrepreneurship success is measured is defined in terms of a broader notion of human flourishing derived from virtue ethics theory. Virtue ethics as a moral theory emphasises positive traits of character shown by habitual action which fit those who have them to lead good lives in terms of a particular notion of professional excellence. In this paper, the writers argue, with reference to virtue ethics, that new measures of success are needed for entrepreneurship, which take into account the key professional concerns, beliefs and features of entrepreneurship. The roles and responsibilities of entrepreneurs enable them to contribute to society in ways that go beyond economic achievements, thus achieving the broad goal of entrepreneurship, human empowerment through opportune innovation, risk-taking and creativity. Having described these specific roles and responsibilities and how they inform the development of a regulative ideal which influences moral purpose and action, the paper goes on to explore the question: what traits of character constitute the entrepreneur who will be well equipped to achieve success as defined? A range of traits which might contribute to entrepreneurial success such as creativity, courage and toughness are suggested and described. The entrepreneur who has these attributes will be an excellent practitioner: one who embodies qualities of character which contribute to the achievement of the proper goals of entrepreneurship

The initiation and development of combustion under cold idling conditions using a glow plug in diesel engines

Factors determining the success or failure of combustion initiation using a glow plug have been investigated through experimental work on a single cylinder, common rail diesel engine with a geometric compression ratio of 15.5, and a quiescent combustion bomb with optical access. A glow plug was required to avoid engine misfires when bulk gas temperature at the start of injection was less than 413 C. The distance between the glow plug and the spray edge, the glow plug temperature, and the bulk gas temperature were important factors in meeting two requirements for successful ignition: a minimum local temperature of 413 C and a minimum air/fuel vapour equivalence ratio of 0.15–0.35

Liomys pictus

Liomys pictus (Thomas, 1893) Painted Spiny Pocket Mous

Prognostic modelling utilizing a high fidelity pressurized water reactor simulator

Within power generation, aging assets and an emphasis on more efficient operation of power systems and improved maintenance decision methods has led to a growing focus on asset prognostics. The main challenge facing the implementation of successful asset prognostics in power generation is the lack of available run-to-failure data. This paper proposes to overcome this issue by use of full-scope high-fidelity simulators to generate the run-to-failure data required. From this simulated failure data a similarity-based prognostic approach is developed for estimating the remaining useful life of a valve asset. Case study data is generated by initializing prebuilt industrial failure models within a 970 MW pressurized water reactor simulation. Such full-scope high-fidelity simulators are mainly operated for training purposes, allowing personnel to gain experience of standard operation as well as failures within a safe, simulated operating environment. This paper repurposes such a high-fidelity simulator to generate the type of data and affects that would be produced in the event of a fault. The fault scenario is then run multiple times to generate a library of failure events. This library of events was then split into training and test batches for building the prognostic model. Results are presented and conclusions drawn about the success of the technique and the use of high-fidelity simulators in this manner

Study of Semi-Span Model Testing Techniques

An investigation has been conducted in the NASA Langley 14- by 22-Foot Subsonic Tunnel in order to further the development of semi-span testing capabilities. A twin engine, energy efficient transport (EET) model with a four-element wing in a takeoff configuration was used for this investigation. Initially a full span configuration was tested and force and moment data, wing and fuselage surface pressure data, and fuselage boundary layer measurements were obtained as a baseline data set. The semi-span configurations were then mounted on the wind tunnel floor, and the effects of fuselage standoff height and shape as well as the effects of the tunnel floor boundary layer height were investigated. The effectiveness of tangential blowing at the standoff/floor juncture as an active boundary-layer control technique was also studied. Results indicate that the semi-span configuration was more sensitive to variations in standoff height than to variations in floor boundary layer height. A standoff height equivalent to 30 percent of the fuselage radius resulted in better correlation with full span data than no standoff or the larger standoff configurations investigated. Undercut standoff leading edges or the use of tangential blowing in the standoff/ floor juncture improved correlation of semi-span data with full span data in the region of maximum lift coefficient

Characterization of the C. elegans erlin homologue

<p>Abstract</p> <p>Background</p> <p>Erlins are highly conserved proteins associated with lipid rafts within the endoplasmic reticulum (ER). Biochemical studies in mammalian cell lines have shown that erlins are required for ER associated protein degradation (ERAD) of activated inositol-1,4,5-trisphosphate receptors (IP3Rs), implying that erlin proteins might negatively regulate IP3R signalling. In humans, loss of erlin function appears to cause progressive intellectual disability, motor dysfunction and joint contractures. However, it is unknown if defects in IP3R ERAD are the underlying cause of this disease phenotype, whether ERAD of activated IP3Rs is the only function of erlin proteins, and what role ERAD plays in regulating IP3R-dependent processes in the context of an intact animal or embryo. In this study, we characterize the erlin homologue of the nematode <it>Caenorhabditis elegans </it>and examine erlin function <it>in vivo</it>. We specifically set out to test whether <it>C. elegans </it>erlin modulates IP3R-dependent processes, such as egg laying, embryonic development and defecation rates. We also explore the possibility that erlin might play a more general role in the ERAD pathway of <it>C. elegans</it>.</p> <p>Results</p> <p>We first show that the <it>C. elegans </it>erlin homologue, ERL-1, is highly similar to mammalian erlins with respect to amino acid sequence, domain structure, biochemical properties and subcellular location. ERL-1 is present throughout the <it>C. elegans </it>embryo; in adult worms, ERL-1 appears restricted to the germline. The expression pattern of ERL-1 thus only partially overlaps with that of ITR-1, eliminating the possibility of ERL-1 being a ubiquitous and necessary regulator of ITR-1. We show that loss of ERL-1 does not affect overall phenotype, or alter brood size, embryonic development or defecation cycle length in either wild type or sensitized <it>itr-1 </it>mutant animals. Moreover we show that ERL-1 deficient worms respond normally to ER stress conditions, suggesting that ERL-1 is not an essential component of the general ERAD pathway.</p> <p>Conclusions</p> <p>Although loss of erlin function apparently causes a strong phenotype in humans, no such effect is seen in <it>C. elegans</it>. <it>C. elegans </it>erlin does not appear to be a ubiquitous major modulator of IP3 receptor activity nor does erlin appear to play a major role in ERAD.</p

A narrative analysis of poetry written from the words of people given a diagnosis of dementia

This study is underpinned by social constructionist epistemology, which points to the socially constructed character of our worlds, in that we co-create and are co-created by (including experience and identity) our social realities. Through narrative analysis of some poems from the words of people given a diagnosis of dementia, this study engaged in the process of meaning-making in relation to Self-construct and the wider social world. Some narratives evidenced speakers’ lack of agency over their experiences, not because of the ‘dementia’ but due to treatment and care contexts. Some narratives provided instances in which others positioned speakers into identity constructions contradictory to their life-long Self-constructs. Other narratives demonstrated that, through acknowledging and supporting ‘personhood’, speakers retained a sense of well-being and purpose in their social worlds. It is hoped that focusing on the words of individuals given dementia diagnoses, away from predominant bio-medical discourses, may facilitate professionals’ continuous reflection and person-centred practice