Does HIV infection have an impact upon dental implant osseointegration? A systematic review

Background: A systematic review is made to determine whether human immunodeficiency virus (HIV) infection has an impact upon dental implant osseointegration. Material and Methods: A PubMed (MEDLINE) literature search was made of articles published up until 14 April 2014. The systematic review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). The quality of the studies included in the review was assessed using the Methodological Index for Nonrandomized Studies (MINORS) and levels of evidence (based on the University of Oxford's Center for Evidence Based Medicine criteria). Results: The combinations of search terms resulted in a list of 132 titles. Nine studies finally met the inclusion criteria and were selected for inclusion in the systematic review. A total of 173 dental implants were placed in 80 patients (135 implants in 56 HIV-positive subjects and 38 implants in 24 HIV-negative patients), and a single loss of dental implant osseointegration was recorded in an HIV-positive patient. Conclusions: Our results suggest that dental implant placement in HIV-positive patients does not increase the dental implant failure rate. Prophylactic antibiotic treatment, the administration of highly active antiretroviral therapy, and control of the CD4+ T lymphocyte counts appear to be the main influencing factors in this respect. Given the few studies included in our systematic review, further prospective studies involving larger sample sizes and longer durations of follow-up are required in order to confirm the results obtained

Adaptation of the Quality of Life Adolescent Cleft Questionnaire for Spanish children and adolescents with cleft lip and/or palate

Background: The Quality of Life Adolescent Cleft Questionnaire is a measure of quality of life in cleft lip/palate (CL/P) including items on pre- treatment and post- treatment status. Items, however, were originally organized in a factor structure that prevents a formal pre- treatment to post- treatment comparison. Additionally, the questionnaire was tested in older patients.Aim: We aimed to explore a factor structure that allows a comparison of pre- to post- treatment status in children and adolescents with CL/P.Design: The sample comprised 60 children and adolescents with CL/P. The scale was divided into two groups of items (24 comparing pre- treatment and post- treatment sta-tus and 26 measuring current quality of life). Two different exploratory and confirm-atory analyses were conducted (one for each group of items). Sources of criterion validity were investigated with measures of self- esteem and self- efficacy.Results: The results supported a 6- factor structure for the pre- treatment and post- treatment items. In the second group of items, 9 items were removed due to inad-equate functioning and a final 4- factor solution was obtained. The criterion validity of factors was good.Conclusion: The proposed factor solution might be more useful to detect the per-ceived satisfaction in different areas and can be used in younger patients