Inestabilidad patelofemoral en niños con Síndrome de Down

La inestabilidad patelofemoral en el síndrome de Down se presenta en el contexto de hiperlaxitud e inmadurez esquelética suponiendo un reto en el tratamiento. Nuestro objetivo es valorar el resultado clínico-funcional de la cirugía de partes blandas, en estos pacientes hiperlaxos e inmaduros esqueléticamente. Hemos revisado retrospectivamente a los pacientes con síndrome de Down e inmadurez esquelética intervenidos por inestabilidad patelofemoral con seguimiento hasta el cierre fisario. Seis pacientes (9 rodillas) con media de edad de 12,4 años fueron incluidos. El grado de inestabilidad patelofemoral prequirúrgica (clasificación de Dugdale) mostró 1 (11,1%) caso grado 2; 2 (22,2%) casos grado 3 y 6 (66,6%) casos grado 4. El grado de función patelar (según Insall) al alcanzar la madurez esquelética fue malo en un caso (recidiva de la luxación), bueno en 2 y excelente en 6. En definitiva, los procedimientos sobre partes blandas pueden ser suficientes en pacientes con síndrome de Down.Patelofemoral instability in Down syndrome´s patients appears in hiperlaxity and open physis context. Our aim is to make a retrospective clinical-functional assessment of the soft tissue procedure treatment of patellofemoral instability in patients with Down Syndrome skeletally immature (open physeal), following them until the physeal closure. We have included six patients (9 knees) with a mean age of 12.4 years old. Patellar instability (Dugdale´s classification) distribution was 1 (11.1%) cases degree ll; 2 (22.2%) cases degree lll and 6 (66.6%) cases degree IV. Patellar function assessed by Insall score at follow up was excellent in 6 of the cases, good in 2 cases and bad in one case (recurrent dislocation). In summary, a proximal soft tissues procedure in Down syndrome patients could be enough for patellar instability treatment

Inferior lateral genicular artery injury during anterior cruciate ligament reconstruction surgery

We report a case of inferior lateral genicular artery (ILG) injury during anterior cruciate ligament (ACL) reconstruction surgery with lateral partial meniscectomy. This is a rare arthroscopy complication. A review of the literature has been made with the aim to define the anatomy of ILG across the lateral articular line and the risk of lesion during knee arthroscopy. We propose embolization as a good treatment option for this type of injurie

Strengthening Synergies: How Action to Achieve Post-2020 Global Biodiversity Conservation Targets Can Contribute to Mitigating Climate Change

The essential contribution of nature to addressing climate change provides an opportunity to strengthen the links between the United Nations Framework Convention on Climate Change and the Convention on Biological Diversity. As we move towards the next Conferences of the Parties of both Conventions, there is a need to assess explicitly the role of nature in helping to meet the goals of these agreements efficiently and effectively. This series of reports aims to shed light on this topic by assessing the potential contribution that achieving biodiversity conservation targets can make to climate change mitigation. By doing so, it aims to provide both context and mandate for discussions under both Conventions on the role of nature-based solutions in climate change mitigation and links to biodiversity conservation action

How are Firms’ Wages and Prices Linked: Survey Evidence in Europe

This paper presents new evidence on the patterns of price and wage adjustment in European firms and on the extent of nominal rigidities. It uses a unique dataset collected through a firm-level survey conducted in a broad range of countries and covering various sectors. Several conclusions are drawn from this evidence. Firms adjust wages less frequently than prices: the former tend to remain unchanged for about 15 months on average, the latter for around 10 months. The degree of price rigidity varies substantially across sectors and depends strongly on economic features, such as the intensity of competition, the exposure to foreign markets and the share of labour costs in total cost. Instead, country specificities, mostly related to the labour market institutional setting, are more relevant in characterising the pattern of wage adjustment. The latter exhibits also a substantial degree of time-dependence, as firms tend to concentrate wage changes in a specific month, mostly January in the majority of countries. Wage and price changes feed into each other at the micro level� and there is a relationship between wage and price rigidity.

Rapid discrimination and classification of edible insect powders using ATR-FTIR spectroscopy combined with multivariate analysis

Insects are being proposed as an alternative way to ensure world''s food and feed security. Methods to determine edible insect powder''s origin and species will be needed for quality control purposes. Infrared spectroscopy has been extensively used in rapid chemical fingerprinting of food products. The present research explores a new approach to discriminate and classify commercial edible insect powders using attenuated total reflectance mid-infrared spectroscopy combined with multivariate analysis. Infrared spectra of seven commercial edible insect powders from different species (Tenebrio molitor, Alphitobius diaperinus, Gryllodes sigillatus, Acheta domesticus and Locusta migratoria) and origins (the Netherlands and New Zealand) were collected to build up soft independent modelling of class analogy (SIMCA) models. SIMCA models clearly discriminated insects by their species and origin linking their differences to lipids and chitin. SIMCA models performance was tested using five spectra of each class not used to build up the training set. 100% correct predictions were obtained for all the samples analysed with the exception of one sample of Alphitobius diaperinus. Infrared spectroscopy coupled to multivariate analysis provided a powerful method for the assurance of insect powder''s authenticity

A global map of terrestrial habitat types

We provide a global, spatially explicit characterization of 47 terrestrial habitat types, as defined in the International Union for Conservation of Nature (IUCN) habitat classification scheme, which is widely used in ecological analyses, including for quantifying species’ Area of Habitat. We produced this novel habitat map for the year 2015 by creating a global decision tree that intersects the best currently available global data on land cover, climate and land use. We independently validated the map using occurrence data for 828 species of vertebrates (35152 point plus 8181 polygonal occurrences) and 6026 sampling sites. Across datasets and mapped classes we found on average a balanced accuracy of 0.77 (+ ¯ 0.14 SD) at Level 1 and 0.71 (+ ¯ 0.15 SD) at Level 2, while noting potential issues of using occurrence records for validation. The maps broaden our understanding of habitats globally, assist in constructing area of habitat refinements and are relevant for broad-scale ecological studies and future IUCN Red List assessments. Periodic updates are planned as better or more recent data becomes available

Application of hand-held near-infrared and Raman spectrometers in surface treatment authentication of cork stoppers

The aim of this paper was to evaluate the potential of using near-infrared (NIR) spectroscopy and multivariate analysis as a rapid tool to non-destructively determine the presence of surface treatments applied to cork stoppers. Density and dimensions of 6 closure varieties were characterized and the extraction force was measured on those produced for still wines. Cork stoppers were also analyzed using hand-held NIR and Raman spectrometers. Soft independent modelling of class analogy (SIMCA) models showed significant differences among treated and untreated samples, linked to components of the coating agents applied (silicone and paraffin). SIMCA model''s classification performance was tested and high sensitivity (93.33 %) and specificity (100 %) values were obtained. Partial least squares regression (PLSR) model accurately predicted the extraction forces measured with low standard error of prediction (SEP = 4.0 daN). Our results are promising for the future application of this technology in cork industry, reducing time and economic losses. © 2021 The Author(s

Rethinking Transnational Activism through Regional Perspectives: Reflections, Literatures and Cases

Copyright \ua9 The Author(s), 2024. Published by Cambridge University Press on behalf of the Royal Historical Society. This collectively authored article argues for a regional turn in the historical study of transnational activism. By considering not only pan-regional movements but also examples of borderland contexts, transregional connections and diasporic understandings of \u27region\u27, our discussion identifies fresh possibilities for investigating the evolution and functioning of transnational activism. Based on a Royal Historical Society-funded workshop held at and supported by Northumbria University, the article brings together insights from diverse locations and arenas of contestation. The first part considers literatures on three macro-regional settings - South Asia, Western Europe and Latin America - to illustrate the importance of distinctive regional contexts and constructs in shaping transnational activism and its goals. The second part turns to case studies of transnational activism in and beyond Eastern Europe, West Africa, the Caribbean and East Asia. In doing so, it explores very different notions of the regional to identify how transnational activism has both shaped and been shaped by these ideas. Taken together, the two parts highlight the role of regional identities and projects in challenging inequalities and external domination. Our analysis and examples indicate the possibilities of a regionally rooted approach for writing histories of transnational activism

Nonreferral of Possible Soft Tissue Sarcomas in Adults: A Dangerous Omission in Policy

Introduction. The aim of this study is to compare outcomes in three groups of STS patients treated in our specialist centre: patients referred immediately after an inadequate initial treatment, patients referred after a local recurrence, and patients referred directly, prior to any treatment. Patients and methods. We reviewed all our nonmetastatic extremity-STS patients with a minimum follow-up of 2 years. We compared three patient groups: those referred directly to our centre (group A), those referred after an inadequate initial excision (group B), and patients with local recurrence (group C). Results. The study included 174 patients. Disease-free survival was 73%, 76%, and 28% in groups A, B, and C, respectively (P < .001). Depth, size, and histologic grade influenced the outcome in groups A and B, but not in C. Conclusion. Initial wide surgical treatment is the main factor that determines local control, being even more important than the known intrinsic prognostic factors of tumour size, depth, and histologic grade. The influence on outcome of initial wide local excision (WLE), which is made possible by referral to a specialist centre, is paramount