Moa and the multi-model architecture: a new perspective on XNF2

Advanced non-traditional application domains such as geographic information systems and digital library systems demand advanced data management support. In an effort to cope with this demand, we present the concept of a novel multi-model DBMS architecture which provides evaluation of queries on complexly structured data without sacrificing efficiency. A vital role in this architecture is played by the Moa language featuring a nested relational data model based on XNF2, in which we placed renewed interest. Furthermore, extensibility in Moa avoids optimization obstacles due to black-box treatment of ADTs. The combination of a mapping of queries on complexly structured data to an efficient physical algebra expression via a nested relational algebra, extensibility open to optimization, and the consequently better integration of domain-specific algorithms, makes that the Moa system can efficiently and effectively handle complex queries from non-traditional application domains

Cognitive and Neurobiological Degeneration of the Mental Lexicon in Primary Progressive Aphasia

The ease with which we use the thousands of words in our vocabulary stands in stark contrast to our difficulty establishing how they are organized in our mind and brain. The breakdown of language due to cortical atrophy in primary progressive aphasia (PPA) creates conditions to study this organization at a cognitive and neurobiological level in that the three variants of this disease, namely non-fluent, logopenic, and semantic PPA, each bear their own signature of language-specific decline and cortical atrophy. As the impaired regions in each variant are linked to different lexical and semantic attributes of words, lexical decision performance of individuals with the distinct variants can reveal the conceptual and neural architecture of the lexicon through an anatomical-behavioral relationship. This dissertation investigated which lexical and semantic factors influence the structural degeneration of word processing in individuals with each variant of PPA through three studies that focused on the role of general semantic knowledge, psycholinguistic variables, and sensory-perceptual features, respectively. In Study 1, 41 individuals with PPA (13 non-fluent, 14 logopenic, and 14 semantic) as well as healthy controls (N = 25) performed a lexical decision task that consisted of 355 real words, carefully controlled on a broad range of psycholinguistic and semantic variables, and 175 pseudowords matched with the real words on the psycholinguistic variables. Two additional non-verbal semantic tasks (Pyramids and Palm Trees test and Over-regular Object Test) were administered to assess semantic ability and its relation with lexical decision performance. Results showed that—contrary to diagnostic expectations for the PPA variants—all three groups of individuals with PPA scored below the performance of matched control participants. The lexical-decision performance across all individuals with PPA correlated with semantic ability, but this correlation was not significant when separately analyzed per diagnosis. These findings suggest that semantic ability plays an active role in word recognition, but is not essential to lexical-semantic processing. In Study 2, the performance of the same participants was analyzed on a selected subset of the 355 words to examine the differential influence of the psycholinguistic factors lexical frequency, age of acquisition, and neighborhood density on lexical-semantic processing across the three diagnostic groups. The results demonstrated that lexical frequency has the largest influence on lexical-semantic processing, but that independent of that, age of acquisition and neighborhood density also play a role. The effect of these two variables becomes more salient dependent on the variant of PPA, accordant to the patterns of atrophy. That is, individuals with non-fluent and logopenic PPA experienced a neighborhood density effect consistent with atrophy in the inferior frontal and temporoparietal cortices, associated with lexical analysis and word form processing. By contrast, individuals with semantic PPA experienced an age of acquisition effect consistent with atrophy in the anterior temporal lobe which has been associated with semantic processing in previous literature. These findings suggest that the degeneration of lexical-semantic processing is affected by lexical factors—which relate to language-specific brain regions—in line with a hierarchical mental lexicon structure, such that a selective deficit at one of the levels of the mental lexicon results in distinctively expressed effects among psycholinguistic variables. Study 3 employed voxel-based morphometry (VBM) to identify the association between cortical volume—measured through T1-weighted magnetic resonance images (MRI)—and lexical decision performance related to sensory-perceptual features in 37 of the individuals with PPA and 17 of the controls on a second subset of the 355 words. Results showed that at both behavioral and neurobiological levels, semantic sensory-perceptual features of words (a strong association with, e.g., sound or action) influence lexical decision performance across all three groups with PPA. The results highlight the roles of the right hemisphere, the cerebellum, and the anterior temporal lobe in processing various sensory-perceptual features of concepts. The anterior temporal lobe has been proposed to be a semantic hub which processes various sensory-perceptual features (‘spokes’) into a conceptual representation in the hub-and-spoke model. The current results confirm this hub-role of the anterior temporal lobe, as well as the link of the ‘spokes’ to sensory-perceptual brain regions, as proposed by the hypothesis of embodied cognition. Most importantly, the results suggest that the intensity of semantic processing in the anterior temporal lobe is regulated by the degree of association with sensory-perceptual information. The current research presents novel evidence that lexical-semantic processing is influenced by a combination of lexical and semantic factors at both conceptual and neurobiological levels, which can become impaired in different ways in individuals with PPA based on a set of anatomical-behavioral relationships. In particular, this dissertation broke new ground in demonstrating that the intensity of semantic processing in the anterior temporal lobe depends on the degree of sensory-perceptual information of concepts, supporting both the hub-and-spoke model and the hypothesis of embodied cognition. As well, this dissertation established the independent effects of lexical frequency from age of acquisition and neighborhood density and their roles in lexical-semantic decline in PPA, supporting the theory of hierarchical distinctions between lexemes and their conceptual representations in the mental lexicon

Contracts for Cross-Organizational Workflow Management

Nowadays, many organizations form dynamic partnerships to deal effectively with market requirements. As companies use automated workflow systems to control their processes, a way of linking workflow processes in different organizations is useful in turning the co-operating companies into a seamless operating virtual enterprise. The CrossFlow Esprit project aims at developing information technology for advanced process support in dynamic virtual organizations with contract based service trading. Contracts are necessary for flexible service outsourcing. This report presents contracts as a way of finding suitable partners, connect WFMSs of different kinds, control outsourced workflow, and share an abstraction of the workflow specification between the partners. The contract defines the data, process, and conditions relevant to the co-operation and the outsourced workflow on an abstract level. This information can be fed through an interface to the WFMSs on both sides of the outsourcing in order to automate fully the co-operation between the partners

Levels of Abstractness in Semantic Noun and Verb Processing:The Role of Sensory‑Perceptual and Sensory‑Motor Information

Effects of concreteness and grammatical class on lexical-semantic processing are well-documented, but the role of sensory-perceptual and sensory-motor features of concepts in underlying mechanisms producing these effects is relatively unknown. We hypothesized that processing dissimilarities in accuracy and response time performance in nouns versus verbs, concrete versus abstract words, and their interaction can be explained by differences in semantic weight—the combined amount of sensory-perceptual and sensory-motor information to conceptual representations—across those grammatical and semantic categories. We assessed performance on concrete and abstract subcategories of nouns and verbs with a semantic similarity judgment task. Results showed that when main effects of concreteness and grammatical class were analyzed in more detail, the grammatical-class effect, in which nouns are processed more accurately and quicker than verbs, was only present for concrete words, not for their abstract counterparts. Moreover, the concreteness effect, measured at different levels of abstract words, was present for both nouns and verbs, but it was less pronounced for verbs. The results do not support the grammatical-class hypothesis, in which nouns and verbs are separately organized, and instead provide evidence in favor of a unitary semantic space, in which lexical-semantic processing is influenced by the beneficial effect of sensory-perceptual and sensory-motor information of concepts

Short communication:Supplementation of fructo-oligosaccharides does not improve insulin sensitivity in heavy veal calves fed different sources of carbohydrates

Heavy veal calves (4–6 mo old) often develop problems with insulin sensitivity. This could lead to metabolic disorders and impaired animal growth performance. Studies in various animal species have shown that the supplementation of short-chain fructo-oligosaccharides (scFOS) can improve insulin sensitivity. We therefore studied the effects of scFOS supplementation on insulin sensitivity in heavy veal calves. Forty male Holstein-Friesian calves (BW = 190 ± 2.9 kg; age = 162 ± 1.4 d at the start of the trial) were fed either a control milk replacer (MR) diet or a diet in which one-third of the lactose was replaced by glucose, fructose, or glycerol for 10 wk prior to the start of the trial. At the start of the trial, calves were subjected to a frequently sampled intravenous glucose tolerance test to assess whole-body insulin sensitivity (muscle and hepatic insulin sensitivity). Calves within each dietary treatment group were ranked based on their insulin sensitivity value. Half of the calves received scFOS (12 mg/kg of BW) with the MR for 6 wk (supplementation was equally distributed over the insulin sensitivity range). Subsequently, a second frequently sampled intravenous glucose tolerance test was conducted to assess the effect of scFOS. In addition, fasting plasma levels of glucose, insulin, triglycerides, and cholesterol were determined to calculate the quantitative insulin sensitivity check index and triglyceride:high-density lipoprotein cholesterol ratio (fasting indicators of insulin sensitivity). Whole-body insulin sensitivity was low at the start of the trial and remained low in all groups [1.0 ± 0.1 and 0.8 ± 0.1 (mU/L)−1 · min−1 on average, respectively]. Supplementation of scFOS did not improve insulin sensitivity in any of the treatment groups. The quantitative insulin sensitivity check index and the triglyceride:high-density lipoprotein cholesterol ratio also did not differ between scFOS and non-scFOS calves and averaged 0.326 ± 0.003 and 0.088 ± 0.004, respectively, at the end of the trial. We conclude that scFOS supplementation does not improve insulin sensitivity in heavy veal calves regardless of the carbohydrate composition of the MR. This is in contrast to other animals (e.g., dogs and horses), where scFOS supplementation did improve insulin sensitivity. The absence of an effect of scFOS might be related to the dosage or to metabolic differences between ruminants and nonruminants. Increasing evidence indicates that dietary interventions in veal calves have little or no effect on insulin sensitivity, possibly because of low levels of insulin sensitivity

Temperatuur en luchtsnelheid op dierniveau

De ideale voeler van de klimaatregelapparatuur is het varken zelf. Liggedrag, kleur van de huid, beharing, hoesten et cetera zijn allemaal belangrijke indicatoren van klimaat. Maar... het zijn wel subjectieve waarnemingen

Moa and the Multi-model architecture: a new perspective on XNF 2

Advanced non-traditional application domains such as geographic information systems and digital library systems demand advanced data management support. In an effort to cope with this demand, we present the concept of a novel multi-model DBMS architecture which provides evaluation of queries on complexly structured data without sacrificing efficiency. A vital role in this architecture is played by the Moa language featuring a nested relational data model based on XNF2 , in which we placed renewed interest. Furthermore, extensibility in Moa avoids optimization obstacles due to black-box treatment of ADTs. The combination of a mapping of queries on complexly structured data to an efficient physical algebra expression via a nested relational algebra, extensibility open to optimization, and the consequently better integration of domain-specific algorithms, makes that the Moa system can efficiently handle complex queries from non-traditional application domains

Effect of restrained versus free drying on hygro-expansion of hardwood and softwood fibers and paper handsheet

Earlier works in literature on the hygro-expansion of paper state that the larger hygro-expansivity of freely compared to restrained dried handsheets is due to structural differences between the fibers inside the handsheet. To unravel this hypothesis, first, the hygro-expansion of freely and restrained dried, hardwood and softwood handsheets has been characterized. Subsequently, the transient full-field hygro-expansion (longitudinal, transverse, and shear strain) of fibers extracted from these handsheets was measured using global digital height correlation, from which the micro-fibril angle was deduced. The hygro-expansivity of each individual fiber was tested before and after a wetting period, during which the fiber's moisture content is maximized, to analyze if a restrained dried fiber can "transform" into a freely dried fiber. It was found that the longitudinal hygro-expansion of the freely dried fibers is significantly larger than the restrained dried fibers, consistent with the sheet-scale differences. The difference in micro-fibril angle between the freely and restrained dried fibers is a possible explanation for this difference, but merely for the hardwood fibers, which are able to "transform" to freely dried fibers after being soaked in water. In contrast, this "transformation" does not happen in softwood fibers, even after full immersion in water for a day. Various mechanisms have been studied to explain the observations on freely and restrained dried hardwood and softwood, fiber and handsheets including analysis of the fibers' lumen and cross-sectional shape. The presented results and discussion deepens the understanding of the differences between freely and restrained dried handsheets.Comment: 43 pages, 15 figures, 2 table

Patterns to Enable Mass-Customized Business Process Monitoring

Mass-customization challenges the one-size-fits-all assumption of mass production, allowing customers to specify the options that best fit their requirements when choosing a product or a service. In business process management, to achieve mass-customization, providers offer to their customers the opportunity to customize the way in which a process will be enacted. We focus on monitoring as a specific customization aspect. We propose a multidimensional classification of modeling patterns for customized monitoring infrastructures. Patterns enable the provider to offer a set of customizable options to customers and design a monitoring infrastructure that fits the preferences specified by customers on such options. An example in the online advertising industry demonstrates how our framework can improve the services currently offered by providers