27 research outputs found

    Effects of pectin liquid on gastroesophageal reflux disease in children with cerebral palsy

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>The use of thickeners is a standard therapy for decreasing episodes of regurgitation or vomiting in infants. However, it remains to be investigated whether thickener is effective for vomiting and/or chronic respiratory symptoms in children with cerebral palsy.</p> <p>Methods</p> <p>We enrolled 18 neurologically impaired children caused by cerebral palsy, with gastroesophageal reflux disease. In the first part of this study (pH monitoring), subjects were randomly allocated to two groups: fed with a high-pectin diet [enteral formula: pectin liquid = 2:1 (v/v)], or a low-pectin diet [enteral formula: pectin liquid = 3:1 (v/v)]. Two-channel esophageal pH monitoring was performed over 48 h. In the second part (clinical trial), subjects were fed a high- or low-pectin diet and non-pectin diet for 4 weeks in a crossover manner. Nurses recorded the feeding volume, number of episodes of vomiting, volume of gastric residue, episodes of cough and wheeze, frequency of using oxygen for dyspnea, and the day when the child could return to school. Cough and wheeze were recorded as a cough-score.</p> <p>Results</p> <p>The median value for the % time pH < 4 at the lower and upper esophagus was significantly decreased with a high-pectin diet [9.2% (6.2–22.6) vs. 5.0% (3.1–13.1); P < 0.01, 3.8% (2.9–11.2) vs. 1.6% (0.9–8.9); P < 0.01 (interquartile range), non-pectin and high-pectin, respectively]. The number of reflux episodes per day and duration of longest reflux were decreased significantly with a high-pectin, but not with a low-pectin diet. The median number of episodes of vomiting decreased significantly with a high-pectin diet [2.5/week (1.0–5.0) vs. 1.0 (1.0–1.5), P < 0.05]. The median cough-score was significantly decreased by both concentrations of pectin [8.5/week (1.0–11.5) vs. 2.0/week (0.0–3.0), fed with a high-pectin diet; 7.0/week (1.0–14.5) vs. 1.0/w (0.0–5.0), fed with a low-pectin diet, P < 0.05].</p> <p>Conclusion</p> <p>Pectin liquid partially decreased gastroesophageal reflux as measured by eshophageal pH monitoring, and might improve vomiting and respiratory symptoms in children with cerebral palsy.</p> <p>Trial registration</p> <p>ISRCTN19787793</p

    Multizenter Studien zur Präeklampsie

    No full text

    Small-scale spatio-temporal characteristics of accumulation rates in western Dronning Maud Land, Antarctica

    No full text
    Spatio-temporal variations of the recently determined accumulation rate are investigated using ground-penetrating radar (GPR) measurements and firn-core studies. The study area is located on Ritscherflya in western Dronning Maud Land, Antarctica, at an elevation range 1400-1560 m. Accumulation rates are derived from internal reflection horizons (IRHs), tracked with GPR, which are connected to a dated firn core. GPR-derived internal layer depths show small relief along a 22 km profile on an ice flowline. Average accumulation rates are about 190 kg m&#8722;2 a&#8722;1 (1980-2005) with spatial variability (1&#963;) of 5% along the GPR profile. The interannual variability obtained from four dated firn cores is one order of magnitude higher, showing 1&#963; standard deviations around 30%. Mean temporal variations of GPR-derived accumulation rates are of the same magnitude or even higher than spatial variations. Temporal differences between 1980-90 and 1990-2005, obtained from two dated IRHs along the GPR profile, indicate temporally non-stationary processes, linked to spatial variations. Comparison with similarly obtained accumulation data from another coastal area in central Dronning Maud Land confirms this observation. Our results contribute to understanding spatio-temporal variations of the accumulation processes, necessary for the validation of satellite data (e.g. altimetry studies and gravity missions such as Gravity Recovery and Climate Experiment (GRACE))

    Child Welfare Workers Who Experience the Death of a Child Client

    No full text
    Annually, almost 2,000 children die from maltreatment; 30%–40% are known to child welfare agencies. Critics attribute these deaths to young, inexperienced, untrained workers. This study used a multi-state sample of 123 child welfare workers who had experienced a fatality to address: 1) the characteristics of workers, 2) how workers approached the case, and 3) the fallout after the fatality. Workers were in their late 30s, were well educated, and had several years of experience. They felt confident in handling the case leading up to the fatality, felt supported by coworkers, and did not use formal support. Implications for administrators are discussed
    corecore