Method of using photovoltaic cell using poly-N-vinylcarbazole complex Patent

Method of producing output voltage from photovoltaic cell using poly-N-vinyl carbazole complexed with iodin

Interpreting two-photon imaging data of lymphocyte motility

Recently, using two-photon imaging it has been found that the movement of B and T cells in lymph nodes can be described by a random walk with persistence of orientation in the range of 2 minutes. We interpret this new class of lymphocyte motility data within a theoretical model. The model considers cell movement to be composed of the movement of subunits of the cell membrane. In this way movement and deformation of the cell are correlated to each other. We find that, indeed, the lymphocyte movement in lymph nodes can best be described as a random walk with persistence of orientation. The assumption of motility induced cell elongation is consistent with the data. Within the framework of our model the two-photon data suggest that T and B cells are in a single velocity state with large stochastic width. The alternative of three different velocity states with frequent changes of their state and small stochastic width is less likely. Two velocity states can be excluded

A model for the study of ligand binding to the ribosomal RNA helix h44.

Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation. Techniques such as selective chemical modification, fluorescence labeling and mutations are cumbersome for the whole ribosome but readily applicable to model RNAs, which are readily crystallized and often give rise to higher resolution crystal structures suitable for detailed analysis of ligand-RNA interactions. Here, we have investigated the HX RNA construct which contains two adjacent ligand binding regions of helix h44 in 16S ribosomal RNA. High-resolution crystal structure analysis confirmed that the HX RNA is a faithful structural model of the ribosomal target. Solution studies showed that HX RNA carrying a fluorescent 2-aminopurine modification provides a model system that can be used to monitor ligand binding to both the ribosomal decoding site and, through an indirect effect, the hygromycin B interaction region

Cutting edge: back to "one-way" germinal centers

The present status of germinal center (GC) research is revisited using in silico simulations based on recent lymphocyte motility data in mice. The generally adopted view of several rounds of somatic hypermutations and positive selection is analyzed with special emphasis on the spatial organization of the GC reaction. We claim that the development of dark zones is not necessary for successful GC reactions to develop. We find that a recirculation of positively selected centrocytes to the dark zone is rather unlikely. Instead we propose a scenario that combines a multiple-step mutation and selection concept with a "one-way" GC in the sense of cell migration

Cherenkov Telescope Array: The next-generation ground-based gamma-ray observatory

High energy gamma-ray astronomy is a newly emerging and very successful branch of astronomy and astrophysics. Exciting results have been obtained by the current generation Cherenkov telescope systems such as H.E.S.S., MAGIC, VERITAS and CANGAROO. The H.E.S.S. survey of the galactic plane has revealed a large number of sources and addresses issues such as the question about the origin of cosmic rays. The detection of very high energy emission from extragalactic sources at large distances has provided insights in the star formation during the history of the universe and in the understanding of active galactic nuclei. The development of the very large Cherenkov telescope array system (CTA) with a sensitivity about an order of magnitude better than current instruments and significantly improved sensitivity is under intense discussion. This observatory will reveal an order of magnitude more sources and due to its higher sensitivity and angular resolution it will be able to detect new classes of objects and phenomena that have not been visible until now. A combination of different telescope types will provide the sensitivity needed in different energy ranges.Comment: 4 pages, 3 figures, to appear in the proceedings of the 30th International Cosmic Ray Conference, Merida, July 200

Static electricity of polymers reduced by treatment with iodine

Treating organic polymers with iodine improves the electrical conductivity. Diffusion enables products of desired properties to be custom formulated. This eliminates a buildup of static electricity and the need for fillers or bound metal salts

Audit on the use of radiological investigations in the management of rhinosinusitis

Objectives: The aim of this audit is to establish the cost to the Maltese health system from the use of radiological imaging in managing rhinosinusitis and to identify areas in which these costs can be minimised by following guidelines on the management of rhinosinusitis. Methods: All plain radiographs and computed tomography scans (CT) of the paranasal sinuses requested in the Mater Dei Hospital over a one year period were analysed. Data was collected regarding: the quantity of investigations ordered, age of the patients, cost and requesting department. Results: Over one year: 205 CT scans and 113 sets of plain radiographs of the paranasal sinuses were requested, costing a total of euro103,440. The majority (73%) were elective requests made by ENT consultants. Five percent of CT scans were requested for patients less than 10 years of age. Conclusion: Rhinosinusitis is diagnosed clinically, only requiring radiological investigation in more complex cases best managed by specialists in ENT. Plain radiographs have limited use in the management of rhinosinusitis. Judicious use of imaging requests whilst following clinical guidelines is required to save money and minimise patient exposure to ionising radiation.peer-reviewe