865 research outputs found

    Difficulties Encountered in Projecting Canada’s Aboriginal Population

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    Enumerating Abelian Returns to Prefixes of Sturmian Words

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    We follow the works of Puzynina and Zamboni, and Rigo et al. on abelian returns in Sturmian words. We determine the cardinality of the set APRu\mathcal{APR}_u of abelian returns of all prefixes of a Sturmian word uu in terms of the coefficients of the continued fraction of the slope, dependingly on the intercept. We provide a simple algorithm for finding the set APRu\mathcal{APR}_u and we determine it for the characteristic Sturmian words.Comment: 19page

    Childhood sexual abuse and adult sexuality

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    Includes bibliographical references (pages [150]-164).The goals of the present study were to define and provide evidence for three types of sexual distortions—dysfunctional sexuality, sexual avoidance, and sexual ambivalence— and to identify factors associated with sexual distortions. Participants were classified into one of four groups (avoidant, dysfunctional, ambivalent, and comparison) based on their scores on measures of erotophilia and erotophobia. The dysfunctional group, relative to the comparison group, was characterized by more sexual behavior, more unrestricted sexual behavior, greater sexual preoccupation, greater dysfunctional sexual attitudes, and acceptance of casual sex. The avoidant group, relative to the comparison group, was characterized by less sexual behavior and more avoidant attitudes toward sex. The ambivalent group, relative to the comparison group, was characterized by more indiscriminant sexual contact, greater dysfunctional sexual attitudes, and more avoidant attitudes toward sex. The ambivalent group was not significantly different from the comparison group on sexual behaviors. CSA victims and nonvictims were compared on sexual distortions, as well as sexual attitudes and behaviors, sexual motivations, adult romantic attachment style, and body image. Results indicated that CSA victims, compared to nonvictims, reported more sex partners, greater sexual variety, and greater use of sex for enhancement, but were not different on sexual distortion variables. CSA characteristics were examined as predictors of sexual distortions. CSA duration, but no other CSA characteristics, significantly predicted dysfunctional sexuality. None of the CSA characteristics examined predicted sexual avoidance or sexual ambivalence. Finally, a path model in which CSA was expected to predict dysfunctional sexuality, sexual avoidance, and sexual ambivalence via motivations for sexual behavior, adult attachment style, and body image was examined. In the final model, having experienced CSA was related to greater sexual ambivalence directly and indirectly via increased use of sex for enhancement. In addition, having experienced CSA was indirectly related to less sexual avoidance via greater use of sex for enhancement. CSA was not directly or indirectly related to dysfunctional sexuality. Anxious attachment, avoidant attachment, and use of sex for coping did not mediate the relationship between CSA and sexual distortions, but were directly related to sexual distortion variables.Ph.D. (Doctor of Philosophy

    The Impacts of Dry Dynamic Cores on Asymmetric Hurricane Intensification

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    The article of record as published may be found at http://dx.doi.org/10.1175/JAS-D-16-0055.1The fundamental pathways for tropical cyclone (TC) intensification are explored by considering axisym- metric and asymmetric impulsive thermal perturbations to balanced, TC-like vortices using the dynamic cores of three different nonlinear numerical models. Attempts at reproducing the results of previous work, which used the community WRF Model, revealed a discrepancy with the impacts of purely asymmetric thermal forcing. The current study finds that thermal asymmetries can have an important, largely positive role on the vortex intensification, whereas other studies find that asymmetric impacts are negligible. Analysis of the spectral energetics of each numerical model indicates that the vortex response to asym- metric thermal perturbations is significantly damped in WRF relative to the other models. Spectral kinetic energy budgets show that this anomalous damping is primarily due to the increased removal of kinetic energy from the vertical divergence of the vertical pressure flux, which is related to the flux of inertia–gravity wave energy. The increased kinetic energy in the other two models is shown to originate around the scales of the heating and propagate upscale with time from nonlinear effects. For very large thermal amplitudes (50 K), the anomalous removal of kinetic energy due to inertia–gravity wave activity is much smaller, resulting in good agreement between models. The results of this paper indicate that the numerical treatment of small-scale processes that project strongly onto inertia–gravity wave energy can lead to significant differences in asymmetric TC intensification. Sensitivity tests with different time integration schemes suggest that diffusion entering into the implicit solution procedure is partly responsible for the anomalous damping of energy.Institute of Geophysics, Planetary Physics and Signatures (IGPPS) at Los Alamos National LaboratoryOffice of Naval Research through program element PE-0602435Institute of Geophysics, Planetary Physics and Signatures (IGPPS) at Los Alamos National LaboratoryOffice of Naval Research through program element PE-060243

    The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids

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    The ultraviolet circular dichroism (CD) spectra of commercial low-molecular-weight heparins, heparinoids and other anticoagulant preparations have been recorded between 180 and 260 nm. Principal component analysis of the spectra allowed their differentiation into a number of groups related to the means of their production reflecting the structural changes introduced by each process. The findings suggest that CD provides a complementary technique for the rapid analysis of heparin preparations

    A Look at Technology Use Across the Country: State Implementation of AT Practices for Infants and Toddlers

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    EI professionals from across the country recently participated in the Tots-n-Tech’s (TnT) Assistive Technology (AT) Program Self-Assessment. Part C Coordinators designated agency and program directors, regional coordinators, or other relevant people in their states to respond to the on-line self assessment of AT practices. The self-assessment is designed to provide a picture of how well recommended AT practices are implemented within state communities. Information from all respondents is combined to provide state-wide and regional views of how programs are doing in making AT available for infants and toddlers with disabilities or delayed development

    Does life satisfaction reduce risk of incident hypertension and stroke? Evidence from the Whitehall II cohort

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    Background: Previous studies showed life satisfaction is related to reduced risk of coronary heart disease and diabetes, but its association with other cardiometabolic endpoints including hypertension and stroke remains unexplored. This study examined life satisfaction's prospective association with incident hypertension and stroke in middle-aged adults. Methods: At baseline (1985–1988), 6225 healthy British civil servants aged 35–55 from the Whitehall II cohort completed the validated Satisfaction with Life Scale and provided information regarding sociodemographics, a range of health-related factors, and psychological distress. Incident hypertension was ascertained according to clinic-derived measures of systolic or diastolic blood pressure of ≥140/90 mmHg, respectively, or self-reports of either physician-diagnosed hypertension or hypertensive medication use. Incident stroke and transient ischemic attack (TIA) were ascertained by self-reported physician diagnosis. Follow-up assessments occurred every 2–5 years through 2017. Cox proportional hazards regression models estimated hazard ratios (HR) and 95% confidence intervals (CI) of hypertension and stroke/TIA risk separately. Results: Over a 31-year follow-up, 2703 cases of hypertension and 370 cases of stroke/TIA occurred. Life satisfaction was not related to risk of developing hypertension but was associated with 12% decreased risk of stroke/TIA after controlling for sociodemographics, health status, and health behaviors (HRper 1-SD = 0.88; 95%CI = 0.79–0.98). However, the association was attenuated after adjustment for psychological distress. Conclusions: No robust associations were found between life satisfaction and incident hypertension and stroke/TIA, respectively, after accounting for well-established risk factors and psychological distress. More research is needed to understand why associations of life satisfaction with cardiometabolic health seem to vary across endpoints

    Urologist burnout: Frequency, causes, and potential solutions to an unspoken entity

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    Physician burnout has been linked to decreased job performance, increased medical errors, interpersonal conflicts, and depression. Recent multispecialty studies suggest that urologists have higher rates (up to 63.6%) of burnout compared to physicians in other specialties; however, these reports were limited by low sample sizes.1 We aimed to evaluate the prevalence of urologist burnout, verify risk factors, and recommend preventative measures and solutions for colleagues at risk or suffering from burnout. Urologist burnout is a true entity that transcends level of training and nationality. Its roots appear to be deep-seated in our tireless efforts to strive for excellence in care for our patients, our growing academic and research pursuits, and surmounting administrative responsibilities; these virtues, which are regarded as the foundations of our career successes, are often obtained at the expense of personal health and wellbeing, as well as family sacrifice. Various other medical societies have become increasingly vocal about the issue of physician burnout and have actively initiated successful strategies to minimize its impact on their members. As an organization with a strong national presence, the Canadian Urological Association (CUA) should promote tools to prevent and interventions to assist those at risk for and suffering from burnout. Increased awareness in the general medical community has led to strategies and tools that can help prevent, identify, or assist physicians in their recovery from burnout. The CUA should develop and facilitate access to information and offer comprehensive support for urologists struggling with burnout

    Heparin Isomeric Oligosaccharide Separation Using Volatile Salt Strong Anion Exchange Chromatography

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    The complexity of heparin and heparan sulfate saccharides makes their purification, including many isomeric structures, very challenging and is a bottleneck for structure–activity studies. High-resolution separations have been achieved by strong anion exchange (SAX) chromatography on Propac PA1 and cetyltrimethylammonium (CTA)-C18 silica columns; however, these entail subsequent desalting methodologies and consequent sample losses and are incompatible with orthogonal chromatography methodologies and, in particular, mass spectrometry. Here, we present the CTA-SAX purification of heparin oligosaccharides using volatile salt (VS) buffer. In VSCTA-SAX, the use of ammonium bicarbonate buffer for elution improves resolution through both weaker dissociation and conformational coordination of the ammonium across the sulfate groups. Using ion mobility mass spectrometry, we demonstrate that isomeric structures have different structural conformations, which makes chromatographic separation achievable. Resolution of such structures is improved compared to standard SAX methods, and in addition, VSCTA-SAX provides an orthogonal method to isolate saccharides with higher purity. Because ammonium bicarbonate is used, the samples can be evaporated rather than desalted, preventing substantial sample loss and allowing more effective subsequent analysis by electrospray mass spectrometry. We conclude that VSCTA-SAX is a powerful new tool that helps address the difficult challenge of heparin/heparan sulfate saccharide separation and will enhance structure–activity studies

    Wind Retrieval Algorithms for the IWRAP and HIWRAP Airborne Doppler Radars with Applications to Hurricanes

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    Algorithms for the retrieval of atmospheric winds in precipitating systems from downward-pointing, conically-scanning airborne Doppler radars are presented. The focus in the paper is on two radars: the Imaging Wind and Rain Airborne Profiler(IWRAP) and the High-altitude IWRAP (HIWRAP). The IWRAP is a dual-frequency (Cand Ku band), multi-beam (incidence angles of 30 50) system that flies on the NOAAWP-3D aircraft at altitudes of 2-4 km. The HIWRAP is a dual-frequency (Ku and Kaband), dual-beam (incidence angles of 30 and 40) system that flies on the NASA Global Hawk aircraft at altitudes of 18-20 km. Retrievals of the three Cartesian wind components over the entire radar sampling volume are described, which can be determined using either a traditional least squares or variational solution procedure. The random errors in the retrievals are evaluated using both an error propagation analysis and a numerical simulation of a hurricane. These analyses show that the vertical and along-track wind errors have strong across-track dependence with values of 0.25 m s-1 at nadir to 2.0 m s-1 and 1.0 m s-1 at the swath edges, respectively. The across-track wind errors also have across-track structure and are on average, 3.0 3.5 m s-1 or 10 of the hurricane wind speed. For typical rotated figure four flight patterns through hurricanes, the zonal and meridional wind speed errors are 2 3 m s-1.Examples of measured data retrievals from IWRAP during an eyewall replacement cycle in Hurricane Isabel (2003) and from HIWRAP during the development of Tropical Storm Matthew (2010) are shown
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