Italian adaptation and psychometric properties of the prejudice against immigrants scale (PAIS): assessment of validity, reliability, and measure invariance

The aim of the current study was to adapt and validate the Prejudice Against Immigrants Scale (PAIS) in the Italian context, based on the Prejudice Against Asylum Seekers Scale by Anderson (2018). The validity, reliability, and measurement invariance across gender, age, and educational levels of the scale were assessed through three sources, which involved 306 Italian individuals (Nmen = 151, 49.3%) between 18 and 60 years old. Both exploratory and confirmatory factor analyses (CFA) confirmed the two-factor solution of the original instrument by excluding two items, which were present in the previous validation study. The first factor is classical prejudice against immigrants, which maps onto theoretical derivations of classical and old-fashioned prejudices, whereas the second factor is conditional prejudice against immigrants, which maps onto theoretical derivations of subtle and modern prejudices. Findings of the multigroup CFAs demonstrated full configural and metric invariance and partial scalar invariance of the scale across gender, age, and educational level. The analyses confirmed that PAIS has high levels of reliability and criterion and construct validity, showing findings that are comparable to those of Anderson (2018). These results suggest that PAIS presents very good psychometric properties and could be considered a valid and reliable instrument to measure prejudice against immigrants, by enabling Italian researchers to detect both covert and more subtle forms of prejudice against immigrants. Limitations and further directions are discussed

Trust and expected costs as antecedents of citizens’ motivation to participate in public policymaking

Objectives. The present study aimed at testing whether costs, trustworthiness of government, and expected voice could predict citizens' willingness to get involved in participatory governance processes. Participants and setting. Research participants were one-hundred and ninety-two volunteer students of Sapienza University of Rome, 66% female. Hypotheses. We hypothesized both main effects of trust (positive) and expected costs (negative) and an interactive effect of the two variables on citizens' willingness to participate. We also expected voice to be a mediator of such an interaction effect on willingness to participate. Statistical analyses. A 2 (costs) by 2 (trust) ANOVA was applied both to manipulation checks and to motivation to participate. Following this, we performed a bootstrap mediated moderation analysis (Hayes, 2013). Results. Motivation to participate was significantly affected by trust, in fact participants in the high trust condition, were more willing to participate (M= 3.84, SD = .91) rather than those in the low trust condition (M = 3.31, SD = .99). Also, a main effect of costs emerged, with low costs inducing higher motivation to participate (M = 3.73, SD = .92) than high costs (M = 3.41, SD = 1.03). More importantly, these effects were qualified by the predicted interaction between costs and trust: while in the high trust condition costs did not affect willingness to participate, in the low costs condition they made a significant difference. Finally, mediated moderation analysis showed that that expected voice was responsible for the impact of the trust by costs interaction on motivation to participate. Limitation. The main limitation of the study concerns generalizability of its results across populations of different ages and occupation

Coverage, Continuity and Visual Cortical Architecture

The primary visual cortex of many mammals contains a continuous representation of visual space, with a roughly repetitive aperiodic map of orientation preferences superimposed. It was recently found that orientation preference maps (OPMs) obey statistical laws which are apparently invariant among species widely separated in eutherian evolution. Here, we examine whether one of the most prominent models for the optimization of cortical maps, the elastic net (EN) model, can reproduce this common design. The EN model generates representations which optimally trade of stimulus space coverage and map continuity. While this model has been used in numerous studies, no analytical results about the precise layout of the predicted OPMs have been obtained so far. We present a mathematical approach to analytically calculate the cortical representations predicted by the EN model for the joint mapping of stimulus position and orientation. We find that in all previously studied regimes, predicted OPM layouts are perfectly periodic. An unbiased search through the EN parameter space identifies a novel regime of aperiodic OPMs with pinwheel densities lower than found in experiments. In an extreme limit, aperiodic OPMs quantitatively resembling experimental observations emerge. Stabilization of these layouts results from strong nonlocal interactions rather than from a coverage-continuity-compromise. Our results demonstrate that optimization models for stimulus representations dominated by nonlocal suppressive interactions are in principle capable of correctly predicting the common OPM design. They question that visual cortical feature representations can be explained by a coverage-continuity-compromise.Comment: 100 pages, including an Appendix, 21 + 7 figure

Coordinated optimization of visual cortical maps (II) Numerical studies

It is an attractive hypothesis that the spatial structure of visual cortical architecture can be explained by the coordinated optimization of multiple visual cortical maps representing orientation preference (OP), ocular dominance (OD), spatial frequency, or direction preference. In part (I) of this study we defined a class of analytically tractable coordinated optimization models and solved representative examples in which a spatially complex organization of the orientation preference map is induced by inter-map interactions. We found that attractor solutions near symmetry breaking threshold predict a highly ordered map layout and require a substantial OD bias for OP pinwheel stabilization. Here we examine in numerical simulations whether such models exhibit biologically more realistic spatially irregular solutions at a finite distance from threshold and when transients towards attractor states are considered. We also examine whether model behavior qualitatively changes when the spatial periodicities of the two maps are detuned and when considering more than 2 feature dimensions. Our numerical results support the view that neither minimal energy states nor intermediate transient states of our coordinated optimization models successfully explain the spatially irregular architecture of the visual cortex. We discuss several alternative scenarios and additional factors that may improve the agreement between model solutions and biological observations.Comment: 55 pages, 11 figures. arXiv admin note: substantial text overlap with arXiv:1102.335

A comparative study of qualitative and quantitative dynamic models of biological regulatory networks

Backgroun

Outcome reporting in randomised controlled trials and meta-analyses of appendicitis treatments in children: a systematic review

Background: Acute appendicitis is the most common surgical emergency in children. Despite this, there is no core outcome set (COS) described for randomised controlled trials (RCTs) in children with appendicitis and hence no consensus regarding outcome selection, definition and reporting. We aimed to identify outcomes currently reported in studies of paediatric appendicitis. / Methods: Using a defined, sensitive search strategy, we identified RCTs and systematic reviews (SRs) of treatment interventions in children with appendicitis. Included studies were all in English and investigated the effect of one or more treatment interventions in children with acute appendicitis or undergoing appendicectomy for presumed acute appendicitis. Studies were reviewed and data extracted by two reviewers. Primary (if defined) and all other outcomes were recorded and assigned to the core areas ‘Death’, ‘Pathophysiological Manifestations’, ‘Life Impact’, ‘Resource Use’ and ‘Adverse Events’, using OMERACT Filter 2.0. / Results: A total of 63 studies met the inclusion criteria reporting outcomes from 51 RCTs and nine SRs. Only 25 RCTs and four SRs defined a primary outcome. A total of 115 unique and different outcomes were identified. RCTs reported a median of nine outcomes each (range 1 to 14). The most frequently reported outcomes were wound infection (43 RCTs, nine SRs), intra-peritoneal abscess (41 RCTs, seven SRs) and length of stay (35 RCTs, six SRs) yet all three were reported in just 25 RCTs and five SRs. Common outcomes had multiple different definitions or were frequently not defined. Although outcomes were reported within all core areas, just one RCT and no SR reported outcomes for all core areas. Outcomes assigned to the ‘Death’ and ‘Life Impact’ core areas were reported least frequently (in six and 15 RCTs respectively). / Conclusions: There is a wide heterogeneity in the selection and definition of outcomes in paediatric appendicitis, and little overlap in outcomes used across studies. A paucity of studies report patient relevant outcomes within the ‘Life Impact’ core area. These factors preclude meaningful evidence synthesis, and pose challenges to designing prospective clinical trials and cohort studies. The development of a COS for paediatric appendicitis is warranted