775 research outputs found

    ANALISIS PENGARUH PENYEMPITAN JALUR JALAN TERHADAP KARAKTERISTIK ARUS LALU LINTAS (STUDIKASUS : Jembatan Ayek Betung Jl. Kapten Sanap Kota Pagar Alam)

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    On several roads in the city of Pagar Alam the road narrowing occurred. In particular, on Bridges often cause problems such as congestion, queues, and delays, it is necessary to know the behavior of traffic flow characteristics such as Volume, Speed, and Density. The primary data survey on the Ayek Bridge section of Jalan Kapten Sanap, Pagar Alam City, was carried out for two Sundays and Mondays with the Manual Count method. Data analysis was based on the 1997 Indonesian Road Capacity Manual (MKJI) using Microsoft Excel software. As for the results of the study obtained the traffic volume for road type 4/2 D (before narrowing) road capacity of 5,643 pcu / hour perlajur, with a value of degree of saturation of 0,15 and service level Type A. Road type 2/2 UD (narrowing) road capacity of 2375 pcu / hour perlajur, with a value of Saturation 0.38 and Service Level Type A, 4/2 UD type road (After Refinement) road capacity of 5130 pcu / hour of service, with a value of 0.20 saturation and level Type A service. The biggest shock wave is obtained on Monday at 07.00-08.00 WIB which is -119.18 km / hour. Negative value is a backward forming shock wave, a backward shock wave occurs towards the arrival of the vehicle. The term 'retreat' means that with time, the shock wave will move backward (upstream or in the direction opposite to the traffic perger). The term 'formed' means that with time, congestion will increase upstream.&nbsp

    RANCANG BANGUN DONGKRAK HIDROLIK PESAWAT CESSNA 152 (PERAWATAN)

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    Di dalam dunia penerbangan, perawatan pesawat terbang sangatlah penting untuk seluruh jenis pesawat termasuk pesawat jenis Cessna-152. Dalam hal perawatannya sendiri dibutuhkan alat-alat yang diantaranya adalah dongkrak hidrolik. Dongkrak tersebut berguna untuk mengangkat pesawat saat perawatan pada bagian landing gear maupun saat akan melakukan pergantian ban. Dan pada pesawat Cessna-152 juga menggunakan dongkrak hidrolik main jack dan bottle jack untuk perawatannya. Bottle jack merupakan dongkrak hidrolik biasa seperti pada umumnya berguna jika ingin melakukan penggantian ban atau sekedar mengisi angin ban pesawat. Sedangkan untuk main jack diperlukan untuk melakukan perawatan yang berat seperti melakukan tes pada landing gear dan pada saat ingin melepas dan memasangnya atau bahkan melakukan perawatan overhaul. Tetapi permasalahannya adalah main jack untuk pesawat Cessna-152 ini sulit ditemukan dan harganya juga tergolong mahal. Maka dari itu penulis membuat alat Dongkrak Hidrolik Pesawat Cessna-152 untuk mempermudah dalam melakukan perawatan pesawat Cessna-152

    Interaksi Trofik Jenis Serangga Di Atas Permukaan Tanah Dan Permukaan Tanah Beberapa Pertanaman Varietas Jagung (Zea Mays Linn.)

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    The aim of the reasearch was to know the tropic interaction of insect on the soil surface and above of soil surface for many varieties of corn (Zea mays Linn.) and index diversity value of insect of corn. The research was conducted in BBI of Tanjung Slamat and Agriculture Pest Laboratory in University of Sumatera Utara, Medan from November (2013) until March (2014). The insect trapped used yellow stiky trap and pitt fall trap. The result of the research showed that insects caught each consist of 9 ordo and 33 family. The highest relative density values in PRG NK603 (application of glyphosate) variety was 16.691% and the lowest was 0.681%. The highest relative density values in PRG NK603 variety was 16.363% and the lowest was 0.578%. The highest relative density values in C7 variety was 15.499 % and the lowest was 0.577 %. The highest relative density values in DK979 variety was 15.073 % and the lowest was 0.450 %. Shanon-Weiner (H') Index diversity value of insect in PRG NK603 (application of glyphosate) variety was 2.950309 (standart), in PRG NK603 was 3.006432 (stable), in C7 variety was 3.051692 (stable), and in DK979 variety was 3.082916 (stable)

    The Role of Public and Private Insurance Expansions and Premiums for Low-Income Parents

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    Numerous states have implemented policies expanding public insurance eligibility or subsidizing private insurance for parents

    STUDY EXPERIMENTAL UNTUK ALAT PENGERING BIJI KOPI TENAGA SURYA SISTEM KONTINU

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    Sebagai salah satu bentuk energi terbarukan, energi surya merupakan salah satu sumber energi yang berpotensi untuk dimanfaatkan terutama di daerah beriklim tropis. Salah satu pemanfaatan energi surya yang paling sering digunakan yaitu pengeringan. Dalam penelitian kali ini pengeringan dilakukan secara kontinu pada kopi dengan media pelat datar bersirip sebagai absorbernya. Menggunakan sel photovoltaic sebagai sumber energi listrik untuk mengalirkan udara panas ke ruang pengering. Adapun tujuan penelitian ini adalah mengetahui efisiensi solar kolektor dan ruang pengering kopi yang diuji, bertujuan agar nantinya dapat digunakan oleh khalayak banyak. Alat ini terdiri dari dua buah kolektor yaitu satu kolektor dengan sudut kemiringan 0o dan yang satu kolektor lain dengan sudut 20o serta rumah pengeringnya. Besar efisiensi kolektor yaitu sebesar 78%. Sedangkan untuk efisiensi rumah pengering adalah sebesar 79%

    LNK (SH2B3): paradoxical effects in ovarian cancer.

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    LNK (SH2B3) is an adaptor protein studied extensively in normal and malignant hematopoietic cells. In these cells, it downregulates activated tyrosine kinases at the cell surface resulting in an antiproliferative effect. To date, no studies have examined activities of LNK in solid tumors. In this study, we found by in silico analysis and staining tissue arrays that the levels of LNK expression were elevated in high-grade ovarian cancer. To test the functional importance of this observation, LNK was either overexpressed or silenced in several ovarian cancer cell lines. Remarkably, overexpression of LNK rendered the cells resistant to death induced by either serum starvation or nutrient deprivation, and generated larger tumors using a murine xenograft model. In contrast, silencing of LNK decreased ovarian cancer cell growth in vitro and in vivo. Western blot studies indicated that overexpression of LNK upregulated and extended the transduction of the mitogenic signal, whereas silencing of LNK produced the opposite effects. Furthermore, forced expression of LNK reduced cell size, inhibited cell migration and markedly enhanced cell adhesion. Liquid chromatography-mass spectroscopy identified 14-3-3 as one of the LNK-binding partners. Our results suggest that in contrast to the findings in hematologic malignancies, the adaptor protein LNK acts as a positive signal transduction modulator in ovarian cancers

    Increasing Eco-Efficiency Awareness for Ship Loading Process Using Virtual Reality and Gamification

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    The world is striving for a sustainable future as United Nations proposed the 17 Sustainable Development Goals to reduce the environmental impact and increase societal wellbeing by 2030. In this endeavor, eco-efficiency is considered as one of the key concept to facilitate the successful transition to the sustainable development with the focus to reduce the ecological impact of industry through efficiency improvements. The shipping industry is largely involved in this challenge with a target set by International Maritime Organization to cut emissions from individual ships by 40% from 2008 levels by 2030. The ship loading process is believed to have great impact to the overall eco-efficiency as it is not only a time consuming process but also determines the fuel consumption of the transportation. In this study, we aim to incorporate virtual reality (VR) technology and gamification theories to raise the eco-efficiency awareness in the shipping loading process. A VR application for ship loading process was developed using a real world case in the Baltic sea region. Eco-efficiency concept is introduced in different levels based on the gamification theories. Maritime professionals tested the VR application and provided their feedback. The results are positive that combining VR and gamification can be useful to train operators with eco-efficiency in ship loading operations. It also shows a huge potential to support the shipping industry in this transition towards a more sustainable future. A VR application for ship loading process was developed using a real world case in the Baltic sea region. Eco-efficiency concept is introduced in different levels based on the gamification theories. Maritime professionals tested the VR application and provided their feedback. The results are positive that combining VR and gamification can be useful to train operators with eco-efficiency in ship loading operations. It also shows a huge potential to support the shipping industry in this transition towards a more sustainable future. A VR application for ship loading process was developed using a real world case in the Baltic sea region. Eco-efficiency concept is introduced in different levels based on the gamification theories. Maritime professionals tested the VR application and provided their feedback. The results are positive that combining VR and gamification can be useful to train operators with eco-efficiency in ship loading operations. It also shows a huge potential to support the shipping industry in this transition towards a more sustainable future. The results are positive that combining VR and gamification can be useful to train operators with eco-efficiency in ship loading operations. It also shows a huge potential to support the shipping industry in this transition towards a more sustainable future. The results are positive that combining VR and gamification can be useful to train operators with eco-efficiency in ship loading operations. It also shows a huge potential to support the shipping industry in this transition towards a more sustainable future

    Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

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    Ciliopathies are human disorders caused by dysfunction of primary cilia, ubiquitous organelles involved in transduction of environmental signals such as light sensation in photoreceptors. Concentration of signal detection proteins such as opsins in the ciliary membrane is achieved by RabGTPase-regulated polarized vesicle trafficking and by a selective barrier at the ciliary base, the transition zone (TZ). Dysfunction of the TZ protein CC2D2A causes Joubert/Meckel syndromes in humans and loss of ciliary protein localization in animal models, including opsins in retinal photoreceptors. The link between the TZ and upstream vesicle trafficking has been little explored to date. Moreover, the role of the small GTPase Rab8 in opsin-carrier vesicle (OCV) trafficking has been recently questioned in a mouse model. Using correlative light and electron microscopy and live imaging in zebrafish photoreceptors, we provide the first live characterization of Rab8-mediated trafficking in photoreceptors in vivo. Our results support a possibly redundant role for both Rab8a/b paralogs in OCV trafficking, based on co-localization of Rab8 and opsins in vesicular structures, and joint movement of Rab8-tagged particles with opsin. We further investigate the role of the TZ protein Cc2d2a in Rab8-mediated trafficking using cc2d2a zebrafish mutants and identify a requirement for Cc2d2a in the latest step of OCV trafficking, namely vesicle fusion. Progressive accumulation of opsin-containing vesicles in the apical portion of photoreceptors lacking Cc2d2a is caused by disorganization of the vesicle fusion machinery at the periciliary membrane with mislocalization and loss of the t-SNAREs SNAP25 and Syntaxin3 and of the exocyst component Exoc4. We further observe secondary defects on upstream Rab8-trafficking with cytoplasmic accumulation of Rab8. Taken together, our results support participation of Rab8 in OCV trafficking and identify a novel role for the TZ protein Cc2d2a in fusion of incoming ciliary-directed vesicles, through organization of the vesicle fusion machinery at the periciliary membrane
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