495 research outputs found

    Anthrax Bioterrorism: Lessons Learned and Future Directions

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    Erratum: Laser-Frequency Stabilization via a Quasimonolithic Mach-Zehnder Interferometer with Arms of Unequal Length and Balanced dc Readout [Phys. Rev. Applied 7, 024027 (2017)]

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    Low frequency high precision laser interferometry is subject to excess laser frequency noise coupling via arm-length differences which is commonly mitigated by locking the frequency to a stable reference system. This is crucial to achieve picometer level sensitivities in the 0.1 mHz to 1 Hz regime, where laser frequency noise is usually high and couples into the measurement phase via arm-length mismatches in the interferometers. Here we describe the results achieved by frequency stabilising an external cavity diode laser to a quasi-monolithic unequal arm-length Mach-Zehnder interferometer read out at mid-fringe via balanced detection. This stabilisation scheme has been found to be an elegant solution combining a minimal number of optical components, no additional laser modulations and relatively low frequency noise levels. The Mach-Zehnder interferometer has been designed and constructed to minimise the influence of thermal couplings and to reduce undesired stray light using the optical simulation tool IfoCAD. We achieve frequency noise levels corresponding to LISA-like (laser interferometer space antenna) displacement sensitivities below 1 pm/Hz\sqrt{\textrm{Hz}} and are able to demonstrate the LISA frequency pre-stabilisation requirement of 300 Hz/Hz\sqrt{\textrm{Hz}} down to frequencies of 100 mHz by beating the stabilised laser with an Iodine locked reference

    Towards a FPGA-controlled deep phase modulation interferometer

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    Deep phase modulation interferometry was proposed as a method to enhance homodyne interferometers to work over many fringes. In this scheme, a sinusoidal phase modulation is applied in one arm while the demodulation takes place as a post-processing step. In this contribution we report on the development to implement this scheme in a fiber coupled interferometer controlled by means of a FPGA, which includes a LEON3 soft-core processor. The latter acts as a CPU and executes a custom made application to communicate with a host PC. In contrast to usual FPGA-based designs, this implementation allows a real-time fine tuning of the parameters involved in the setup, from the control to the post-processing parameters.Comment: Proceedings of the X LISA Symposium, Gainesville, May 18-23, 201

    Design and construction of an optical test bed for LISA imaging systems and tilt-to-length coupling

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    The laser interferometer space antenna (LISA) is a future space-based interferometric gravitational-wave detector consisting of three spacecraft in a triangular configuration. The interferometric measurements of path length changes between satellites will be performed on optical benches in the satellites. Angular misalignments of the interfering beams couple into the length measurement and represent a significant noise source. Imaging systems will be used to reduce this tilt-to-length coupling. We designed and constructed an optical test bed to experimentally investigate tilt-to-length coupling. It consists of two separate structures, a minimal optical bench and a telescope simulator. The minimal optical bench comprises the science interferometer where the local laser is interfered with light from a remote spacecraft. In our experiment, a simulated version of this received beam is generated on the telescope simulator. The telescope simulator provides a tilting beam, a reference interferometer and an additional static beam as a phase reference. The tilting beam can either be a flat-top beam or a Gaussian beam. We avoid tilt-to-length coupling in the reference interferometer by using a small photo diode placed at an image of the beam rotation point. We show that the test bed is operational with an initial measurement of tilt-to-length coupling without imaging systems. Furthermore, we show the design of two different imaging systems whose performance will be investigated in future experiments

    Disease Control and Prevention

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    — i — Some thoughts about traumatic brain injury (TBI) data… …People are uneducated about traumatic brain injury. They don’t recognize it when it happens to them or their loved ones; they don’t know the extent of the public health problem…. This is my dream for people who will sustain a traumatic brain injury: ….At the time the TBI is diagnosed,…the injured person receives information about the consequences of traumatic brain injury and sources of education and support. ….All traumatic brain injuries will be counted, including mild TBIs. The Centers for Disease Control and Prevention will develop

    Self-Reported Occupational Exposure to HIV and Factors Influencing its Management Practice: A Study of Healthcare Workers in Tumbi and Dodoma Hospitals, Tanzania.

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    Blood borne infectious agents such as hepatitis B virus (HBV), hepatitis C virus (HCV) and human immune deficiency virus (HIV) constitute a major occupational hazard for healthcare workers (HCWs). To some degree it is inevitable that HCWs sustain injuries from sharp objects such as needles, scalpels and splintered bone during execution of their duties. However, in Tanzania, there is little or no information on factors that influence the practice of managing occupational exposure to HIV by HCWs. This study was conducted to determine the prevalence of self-reported occupational exposure to HIV among HCWs and explore factors that influence the practice of managing occupational exposure to HIV by HCWs in Tanzania. Self-administered questionnaire was designed to gather information of healthcare workers' occupational exposures in the past 12 months and circumstances in which these injuries occurred. Practice of managing occupational exposure was assessed by the following questions: Nearly half of the HCWs had experienced at least one occupational injury in the past 12 months. Though most of the occupational exposures to HIV were experienced by female nurses, non-medical hospital staff received PEP more frequently than nurses and doctors. Doctors and nurses frequently encountered occupational injuries in surgery room and labor room respectively. HCWs with knowledge on the possibility of HIV transmission and those who knew whom to contact in event of occupational exposure to HIV were less likely to have poor practice of managing occupational exposure. Needle stick injuries and splashes are common among HCWs at Tumbi and Dodoma hospitals. Knowledge of the risk of HIV transmission due to occupational exposure and knowing whom to contact in event of exposure predicted practice of managing the exposure. Thus provision of health education on occupational exposure may strengthen healthcare workers' practices to manage occupational exposure

    Readout for intersatellite laser interferometry: Measuring low frequency phase fluctuations of HF signals with microradian precision

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    Precision phase readout of optical beat note signals is one of the core techniques required for intersatellite laser interferometry. Future space based gravitational wave detectors like eLISA require such a readout over a wide range of MHz frequencies, due to orbit induced Doppler shifts, with a precision in the order of μrad/Hz\mu \textrm{rad}/\sqrt{\textrm{Hz}} at frequencies between 0.1mHz0.1\,\textrm{mHz} and 1Hz1\,\textrm{Hz}. In this paper, we present phase readout systems, so-called phasemeters, that are able to achieve such precisions and we discuss various means that have been employed to reduce noise in the analogue circuit domain and during digitisation. We also discuss the influence of some non-linear noise sources in the analogue domain of such phasemeters. And finally, we present the performance that was achieved during testing of the elegant breadboard model of the LISA phasemeter, that was developed in the scope of an ESA technology development activity.Comment: submitted to Review of Scientific Instruments on April 30th 201

    Experimental Demonstration of Reduced Tilt-to-length Coupling by Using Imaging Systems in Precision Interferometers

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    Angular misalignment of one of the interfering beams in laser interferometers can couple into the interferometric length measurement and is called tilt-to-length (TTL) coupling in the following. In the noise budget of the planned space-based gravitational-wave detector evolved Laser Interferometer Space Antenna (eLISA) [1, 2] TTL coupling is the second largest noise source after shot noise [3

    Optical suppression of tilt-to-length coupling in the LISA long-arm interferometer

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    The arm length and the isolation in space enable the Laser Interferometer Space Antenna (LISA) to probe for signals unattainable on the ground, opening a window to the subhertz gravitational-wave universe. The coupling of unavoidable angular spacecraft jitter into the longitudinal displacement measurement, an effect known as tilt-to-length (TTL) coupling, is critical for realizing the required sensitivity of picometer / √ Hz . An ultrastable interferometer test bed has been developed in order to investigate this issue and validate mitigation strategies in a setup representative of LISA and in this paper it is operated in the long-arm interferometer configuration. The test bed is fitted with a flat-top beam generator to simulate the beam received by a LISA spacecraft. We demonstrate a reduction of TTL coupling between this flat-top beam and a Gaussian reference beam via the introduction of two- and four-lens imaging systems. TTL coupling factors below ± 25 μ m / rad for beam tilts within ± 300 μ rad are obtained by careful optimization of the system. Moreover, we show that the additional TTL coupling due to lateral-alignment errors of elements of the imaging system can be compensated by introducing lateral shifts of the detector and vice versa. These findings help validate the suitability of this noise-reduction technique for the LISA long-arm interferometer
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