521 research outputs found
Properties of active galactic star-forming regions probed by imaging spectroscopy with the Fourier transform spectrometer (FTS) onboard AKARI
We investigate the structure of the interstellar medium (ISM) and identify
the location of possible embedded excitation sources from far-infrared (FIR)
line and mid-infrared continuum emission maps. We carried out imaging
spectroscopic observations of four giant Galactic star-forming regions with the
Fourier Transform Spectrometer (FTS) onboard AKARI. We obtained [OIII] 88
micron and [CII] 158 micron line intensity maps of all the regions:
G3.270-0.101, G333.6-0.2, NGC3603, and M17. For G3.270-0.101, we obtained
high-spatial-resolution [OIII] 88 micron line-emission maps and a FIR continuum
map for the first time, which imply that [OIII] 88 micron emission identifies
the excitation sources more clearly than the radio continuum emission. In
G333.6-0.2, we found a local [OIII] 88 micron emission peak, which is
indicative of an excitation source. This is supported by the 18 micron
continuum emission, which is considered to trace the hot dust distribution. For
all regions, the [CII] 158 micron emission is distributed widely as suggested
by previous observations of star-forming regions. We conclude that [OIII] 88
micron emission traces the excitation sources more accurately than the radio
continuum emission, especially where there is a high density and/or column
density gradient. The FIR spectroscopy provides a promising means of
understanding the nature of star-forming regions.Comment: 14 pages with 15 figures, accepted for publication in Astronomy and
Astrophysic
Resolved 24.5 micron emission from massive young stellar objects
Massive young stellar objects (MYSO) are surrounded by massive dusty
envelopes. Our aim is to establish their density structure on scales of ~1000
AU, i.e. a factor 10 increase in angular resolution compared to similar studies
performed in the (sub)mm. We have obtained diffraction-limited (0.6") 24.5
micron images of 14 well-known massive star formation regions with
Subaru/COMICS. The images reveal the presence of discrete MYSO sources which
are resolved on arcsecond scales. For many sources, radiative transfer models
are capable of satisfactorily reproducing the observations. They are described
by density powerlaw distributions (n(r) ~ r^(-p)) with p = 1.0 +/-0.25. Such
distributions are shallower than those found on larger scales probed with
single-dish (sub)mm studies. Other sources have density laws that are
shallower/steeper than p = 1.0 and there is evidence that these MYSOs are
viewed near edge-on or near face-on, respectively. The images also reveal a
diffuse component tracing somewhat larger scale structures, particularly
visible in the regions S140, AFGL 2136, IRAS 20126+4104, Mon R2, and Cep A. We
thus find a flattening of the MYSO envelope density law going from ~10 000 AU
down to scales of ~1000 AU. We propose that this may be evidence of rotational
support of the envelope (abridged).Comment: 21 pages, accepted for A&
Liquid-vapor oscillations of water in hydrophobic nanopores
Water plays a key role in biological membrane transport. In ion channels and
water-conducting pores (aquaporins), one dimensional confinement in conjunction
with strong surface effects changes the physical behavior of water. In
molecular dynamics simulations of water in short (0.8 nm) hydrophobic pores the
water density in the pore fluctuates on a nanosecond time scale. In long
simulations (460 ns in total) at pore radii ranging from 0.35 nm to 1.0 nm we
quantify the kinetics of oscillations between a liquid-filled and a
vapor-filled pore. This behavior can be explained as capillary evaporation
alternating with capillary condensation, driven by pressure fluctuations in the
water outside the pore. The free energy difference between the two states
depends linearly on the radius. The free energy landscape shows how a
metastable liquid state gradually develops with increasing radius. For radii
larger than ca. 0.55 nm it becomes the globally stable state and the vapor
state vanishes. One dimensional confinement affects the dynamic behavior of the
water molecules and increases the self diffusion by a factor of two to three
compared to bulk water. Permeabilities for the narrow pores are of the same
order of magnitude as for biological water pores. Water flow is not continuous
but occurs in bursts. Our results suggest that simulations aimed at collective
phenomena such as hydrophobic effects may require simulation times longer than
50 ns. For water in confined geometries, it is not possible to extrapolate from
bulk or short time behavior to longer time scales.Comment: 20 pages, 4 figures, 3 tables; to be published in Proc. Natl. Acad.
Sci. US
Interpenetrated polymer networks of Poly(β-cyclodextrin) and Polyvinylpyrrolidone with synergistic and selective sorption capacities
Interpenetrating polymer network (IPN) hydrogels were synthesised using β-cyclodextrin (β-CD) and N-vynil-2-pyrrolidone (NVP) crosslinked with epichlorohydrin and divinylbenzene, respectively, and prepared by four different procedures: simultaneous, sequential, hybrid and a novel one named hybrid-sequential.
The IPNs prepared have been characterised by infrared spectroscopy and thermal analysis. The equilibrium swelling in water and the sorption of model substances into the IPNs have also been studied. The model sorbates (1-naphthol, 2-acetylnaphthalene and tannic acid) were selected according to the affinities towards each one of the two constituent polymers.
Our studies reveal that these IPNs can be applied for the sorption of substances that can interact with the network by two mechanisms, i.e. inclusion within cyclodextrin cavities and/or via specific interactions with the functional groups present. Besides, due to the complementary character of their constituent polymers, these networks could also serve to retain two substances of different nature such as cetirizine and pseudoephedrine
Ectopic cardiovascular fat in middle-aged men: effects of race/ethnicity, overall and central adiposity. The ERA JUMP study.
Background/objectivesHigher volumes of ectopic cardiovascular fat (ECF) are associated with greater risk of coronary heart disease (CHD). Identifying factors that are associated with ECF volumes may lead to new preventive efforts to reduce risk of CHD. Significant racial/ethnic differences exist for overall and central adiposity measures, which are known to be associated with ECF volumes. Whether racial/ethnic differences also exist for ECF volumes and their associations with these adiposity measures remain unclear.Subjects/methodsBody mass index (BMI), computerized tomography-measured ECF volumes (epicardial, pericardial and their summation) and visceral adipose tissue (VAT) were examined in a community-based sample of 1199 middle-aged men (24.2% Caucasians, 7.0% African-Americans, 23.6% Japanese-Americans, 22.0% Japanese, 23.2% Koreans).ResultsSignificant racial/ethnic differences existed in ECF volumes and their relationships with BMI and VAT. ECF volumes were the highest among Japanese-Americans and the lowest among African-Americans. The associations of BMI and VAT with ECF differed by racial/ethnic groups. Compared with Caucasians, for each 1-unit increase in BMI, African-Americans had lower, whereas Koreans had higher increases in ECF volumes (P-values<0.05 for both). Meanwhile, compared with Caucasians, for each 1-unit increase in log-transformed VAT, African-Americans, Japanese-Americans and Japanese had similar increases, whereas Koreans had a lower increase in ECF volumes (P-value<0.05).ConclusionsRacial/ethnic groups differed in their propensity to accumulate ECF at increasing level of overall and central adiposity. Future studies should evaluate whether reducing central adiposity or overall weight will decrease ECF volumes more in certain racial/ethnic groups. Evaluating these questions might help in designing race-specific prevention strategy of CHD risk associated with higher ECF
Ex Situ Machine Perfusion of Human Donor Livers via the Surgically Reopened Umbilical Vein:A Proof of Concept
Background. Machine perfusion of donor livers is typically performed via the portal vein main stem. Instead, cannulation of a reopened umbilical vein could allow machine perfusion during organ procurement and subsequent implantation in the recipient without interruption of the portal venous circulation. We aimed to assess the feasibility of portal venous machine perfusion via the umbilical vein. Methods. During back table inspection of 5 human livers declined for transplantation, the umbilical vein was surgically reopened, dilated, and cannulated. Hypothermic and normothermic oxygenated machine perfusion (NMP) were performed using the umbilical vein for portal inflow. Three livers were perfused with hypothermic machine perfusion, 1 full liver graft underwent NMP for 4 hours, and 1 left lateral split procedure was performed under continuous NMP with portal perfusion via the umbilical vein. Results. In all livers, access to the portal venous system via the umbilical vein was successfully achieved with good portal flows and macroscopically homogeneous perfusion. The full liver graft that underwent NMP via the umbilical vein for 4 hours showed good lactate clearance, normalized pH, and achieved good bile production with pH >7.55. During the split procedure under continuous NMP via the umbilical vein, the left lateral segment and extended right lobe remained equally perfused, as demonstrated by Doppler ultrasound. Conclusions. Machine perfusion with portal perfusion via the umbilical vein is feasible. Portal venous flows were similar to those obtained after cannulation of the portal vein main stem. This technique enables continuous oxygenated perfusion of liver grafts during procurement, splitting, and implantation
- …