752 research outputs found
Spin-orbital Kondo decoherence by environmental effects in capacitively coupled quantum dot devices
Strong correlation effects in a capacitively coupled double quantum-dot setup
were previously shown to provide the possibility of both entangling spin-charge
degrees of freedom and realizing efficient spin-filtering operations by static
gate-voltage manipulations. Motivated by the use of such a device for quantum
computing, we study the influence of electromagnetic noise on a general
spin-orbital Kondo model, and investigate the conditions for observing
coherent, unitary transport, crucial to warrant efficient spin manipulations.
We find a rich phase diagram, where low-energy properties sensitively depend on
the impedance of the external environment and geometric parameters of the
system. Relevant energy scales related to the Kondo temperature are also
computed in a renormalization-group treatment, allowing to assess the
robustness of the device against environmental effects.Comment: 13 pages, 13 figures. Minor modifications in V
The mRNA-bound proteome of the human malaria parasite Plasmodium falciparum.
BackgroundGene expression is controlled at multiple levels, including transcription, stability, translation, and degradation. Over the years, it has become apparent that Plasmodium falciparum exerts limited transcriptional control of gene expression, while at least part of Plasmodium's genome is controlled by post-transcriptional mechanisms. To generate insights into the mechanisms that regulate gene expression at the post-transcriptional level, we undertook complementary computational, comparative genomics, and experimental approaches to identify and characterize mRNA-binding proteins (mRBPs) in P. falciparum.ResultsClose to 1000 RNA-binding proteins are identified by hidden Markov model searches, of which mRBPs encompass a relatively large proportion of the parasite proteome as compared to other eukaryotes. Several abundant mRNA-binding domains are enriched in apicomplexan parasites, while strong depletion of mRNA-binding domains involved in RNA degradation is observed. Next, we experimentally capture 199 proteins that interact with mRNA during the blood stages, 64 of which with high confidence. These captured mRBPs show a significant overlap with the in silico identified candidate RBPs (p < 0.0001). Among the experimentally validated mRBPs are many known translational regulators active in other stages of the parasite's life cycle, such as DOZI, CITH, PfCELF2, Musashi, and PfAlba1-4. Finally, we also detect several proteins with an RNA-binding domain abundant in Apicomplexans (RAP domain) that is almost exclusively found in apicomplexan parasites.ConclusionsCollectively, our results provide the most complete comparative genomics and experimental analysis of mRBPs in P. falciparum. A better understanding of these regulatory proteins will not only give insight into the intricate parasite life cycle but may also provide targets for novel therapeutic strategies
On the slice genus of links
We define Casson-Gordon sigma-invariants for links and give a lower bound of
the slice genus of a link in terms of these invariants. We study as an example
a family of two component links of genus h and show that their slice genus is
h, whereas the Murasugi-Tristram inequality does not obstruct this link from
bounding an annulus in the 4-ball.Comment: Published by Algebraic and Geometric Topology at
http://www.maths.warwick.ac.uk/agt/AGTVol3/agt-3-30.abs.htm
Gate-tuned high frequency response of carbon nanotube Josephson junctions
Carbon nanotube (CNT) Josephson junctions in the open quantum dot limit
exhibit superconducting switching currents which can be controlled with a gate
electrode. Shapiro voltage steps can be observed under radiofrequency current
excitations, with a damping of the phase dynamics that strongly depends on the
gate voltage. These measurements are described by a standard RCSJ model showing
that the switching currents from the superconducting to the normal state are
close to the critical current of the junction. The effective dynamical
capacitance of the nanotube junction is found to be strongly gate-dependent,
suggesting a diffusive contact of the nanotube.Comment: 14 pages, 8 figure
Mean-field phase diagram of interacting e_g electrons
We investigate the magnetic phase diagram of the two-dimensional model for
e_g electrons which describes layered nickelates. One finds a generic tendency
towards magnetic order accompanied by orbital polarization. For two equivalent
orbitals with diagonal hopping such orbitally polarized phases are induced by
finite crystal field.Comment: 2 pages, 2 figure
Nonlocal correlations of the local density of states in disordered quantum Hall systems
Motivated by recent high-resolution scanning tunneling microscopy (STM)
experiments in the quantum Hall regime both on massive two-dimensional electron
gas and on graphene, we consider theoretically the disorder averaged nonlocal
correlations of the local density of states (LDoS) for electrons moving in a
smooth disordered potential in the presence of a high magnetic field. The
intersection of two quantum cyclotron rings around the two different positions
of the STM tip, correlated by the local disorder, provides peaks in the spatial
dispersion of the LDoS-LDoS correlations when the intertip distance matches the
sum of the two quantum Larmor radii. The energy dependence displays also
complex behavior: for the local LDoS-LDoS average (i.e., at coinciding tip
positions), sharp positive correlations are obtained for tip voltages near
Landau level, and weak anticorrelations otherwise.Comment: 11 pages, 8 figures ; v2: 2 references added and small extension of
conclusion, similar to published versio
Universal transport signatures in two-electron molecular quantum dots: gate-tunable Hund's rule, underscreened Kondo effect and quantum phase transitions
We review here some universal aspects of the physics of two-electron
molecular transistors in the absence of strong spin-orbit effects. Several
recent quantum dots experiments have shown that an electrostatic backgate could
be used to control the energy dispersion of magnetic levels. We discuss how the
generically asymmetric coupling of the metallic contacts to two different
molecular orbitals can indeed lead to a gate-tunable Hund's rule in the
presence of singlet and triplet states in the quantum dot. For gate voltages
such that the singlet constitutes the (non-magnetic) ground state, one
generally observes a suppression of low voltage transport, which can yet be
restored in the form of enhanced cotunneling features at finite bias. More
interestingly, when the gate voltage is controlled to obtain the triplet
configuration, spin S=1 Kondo anomalies appear at zero-bias, with non-Fermi
liquid features related to the underscreening of a spin larger than 1/2.
Finally, the small bare singlet-triplet splitting in our device allows to
fine-tune with the gate between these two magnetic configurations, leading to
an unscreening quantum phase transition. This transition occurs between the
non-magnetic singlet phase, where a two-stage Kondo effect occurs, and the
triplet phase, where the partially compensated (underscreened) moment is akin
to a magnetically "ordered" state. These observations are put theoretically
into a consistent global picture by using new Numerical Renormalization Group
simulations, taylored to capture sharp finie-voltage cotunneling features
within the Coulomb diamonds, together with complementary out-of-equilibrium
diagrammatic calculations on the two-orbital Anderson model. This work should
shed further light on the complicated puzzle still raised by multi-orbital
extensions of the classic Kondo problem.Comment: Review article. 16 pages, 17 figures. Minor corrections and extra
references added in V
Classical percolation fingerprints in the high-temperature regime of the integer quantum Hall effect
We have performed magnetotransport experiments in the high-temperature regime
(up to 50 K) of the integer quantum Hall effect for two-dimensional electron
gases in semiconducting heterostructures. While the magnetic field dependence
of the classical Hall law presents no anomaly at high temperatures, we find a
breakdown of the Drude-Lorentz law for the longitudinal conductance beyond a
crossover magnetic field B_c ~ 1 T, which turns out to be correlated with the
onset of the integer quantum Hall effect at low temperatures. We show that the
high magnetic field regime at B > B_c can be understood in terms of classical
percolative transport in a smooth disordered potential. From the temperature
dependence of the peak longitudinal conductance, we extract scaling exponents
which are in good agreement with the theoretically expected values. We also
prove that inelastic scattering on phonons is responsible for dissipation in a
wide temperature range going from 1 to 50 K at high magnetic fields.Comment: 14 pages + 8 Figure
Influence of spin fluctuations near the Mott transition: a DMFT study
Dynamics of magnetic moments near the Mott metal-insulator transition is
investigated by a combined slave-rotor and Dynamical Mean-Field Theory solution
of the Hubbard model with additional fully-frustrated random Heisenberg
couplings. In the paramagnetic Mott state, the spinon decomposition allows to
generate a Sachdev-Ye spin liquid in place of the collection of independent
local moments that typically occurs in the absence of magnetic correlations.
Cooling down into the spin-liquid phase, the onset of deviations from pure
Curie behavior in the spin susceptibility is found to be correlated to the
temperature scale at which the Mott transition lines experience a marked
bending. We also demonstrate a weakening of the effective exchange energy upon
approaching the Mott boundary from the Heisenberg limit, due to quantum
fluctuations associated to zero and doubly occupied sites.Comment: 6 pages, 3 figures. V3 was largely expande
Magnetotransport in the Kondo model with ferromagnetic exchange interaction
We consider the transport properties in an applied magnetic field of the spin
S=1/2 Kondo model with ferromagnetic exchange coupling to electronic
reservoirs, a description relevant for the strong coupling limit of
underscreened spin S=1 Kondo impurities. Because the ferromagnetic Kondo
interaction is marginally irrelevant, perturbative methods should prove
accurate down to low energies. For the purpose of this study, we use a
combination of Majorana diagrammatic theory with Density Matrix Numerical
Renormalization Group simulations. In the standard case of antiferromagnetic
Kondo exchange, we first show that our technique recovers previously obtained
results for the T-matrix and spin relaxation at weak coupling (above the Kondo
temperature). Considering then the ferromagnetic case, we demonstrate how the
low-energy Kondo anomaly splits for arbitrary small values of the Zeeman
energy, in contrast to fully screened Kondo impurities near the strong coupling
Fermi liquid fixed point, and in agreement with recent experimental findings
for spin S=1 molecular quantum dots.Comment: 14 pages, 13 figures, minor changes in V
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