Recent H-alpha results on pulsar B2224+65's bow-shock nebula, the "Guitar"

We used the 4 m Discovery Channel Telescope (DCT) at Lowell observatory in 2014 to observe the Guitar Nebula, an Hα bow-shock nebula around the high-velocity radio pulsar B2224+65. Since the nebula`s discovery in 1992, the structure of the bow-shock has undergone significant dynamical changes. We have observed the limb structure, targeting the "body" and "neck" of the guitar. Comparing the DCT observations to 1995 observations with the Palomar 200-inch Hale telescope, we found changes in both spatial structure and surface brightness in the tip, head, and body of the nebula

Higher education students’ media usage: A longitudinal analysis

Responding to the lack of longitudinal analyses on media usage in higher education, this study explores the changes of higher education students’ access to and use of technology for learning in 2012, 2015 and 2018. Using an online questionnaire, a total of 5,572 German higher education students participated. Via descriptive and inferential analysis, the data show a clear trend towards using flexible, location-independent devices, accompanied by a rapid increase in the use of instant messaging. This is in line with an increasing demand for digital and flexible learning opportunities such as web-based training and lectures as podcasts or vodcasts, which is not met by higher education institutions. On that basis, improvements in development and application of these digital tools seem crucial for German higher education institutions and should be considered by educational technologists and decision makers. Of particular relevance against the background of the COVID-19 pandemic that started in Spring 2020, this longitudinal analysis provides a framework for the ongoing development and implementation of digital media in teaching and learning at higher education institutions

Higher education students’ media usage: A longitudinal analysis

Responding to the lack of longitudinal analyses on media usage in higher education, this study explores the changes of higher education students’ access to and use of technology for learning in 2012, 2015 and 2018. Using an online questionnaire, a total of 5,572 German higher education students participated. Via descriptive and inferential analysis, the data show a clear trend towards using flexible, location-independent devices, accompanied by a rapid increase in the use of instant messaging. This is in line with an increasing demand for digital and flexible learning opportunities such as web-based training and lectures as podcasts or vodcasts, which is not met by higher education institutions. On that basis, improvements in development and application of these digital tools seem crucial for German higher education institutions and should be considered by educational technologists and decision makers. Of particular relevance against the background of the COVID-19 pandemic that started in Spring 2020, this longitudinal analysis provides a framework for the ongoing development and implementation of digital media in teaching and learning at higher education institutions

Improving livelihoods, training para-ecologists, enthralling children: Earning trust for effective community- based biodiversity conservation in Andasibe, eastern Madagascar

The rainforests of eastern Madagascar are shrinking due to population growth, poverty-driven land degradation and widespread ignorance of ecological dynamics. This has resulted in large-scale transformation and fragmentation of these forests, threatening their unique biodiversity. Many of these problems are also manifest in and around the village of Andasibe. Based on the example of Association Mitsinjo, and drawing from more than a decade of experience of community-based natural resource management in Andasibe, we highlight the challenges and successes of a community-run conservation organization that builds trust through a holistic approach resting on five building blocks: (i) management transfer of natural resources to the local community, (ii) community-based nature tourism, (iii) training of para-scientists, (iv) rainforest restoration and improving local livelihoods, and (v) environmental education. This has resulted in the creation and legal protection of two community-run reserves, Analamazaotra and Torotorofotsy, accompanied by ecological monitoring programs. We illustrate how handing over responsibilities to local communities can be a promising approach to conserving natural resources and biodiversity in Madagascar and elsewhere. La superficie des forêts tropicales de l’est de Madagascar diminue avec la croissance démographique, la dégradation des terres par effet de la pauvreté, ainsi que par l'ignorance générale des interrelations écologiques. Tout cela a abouti à une transformation profonde et étendue ainsi qu’à la fragmentation de ces forêts qui menacent leur biodiversité. Ces problèmes globaux sont pour la plupart rencontrés à la périphérie du village d'Andasibe. Ici, l’exemple de l'Association Mitsinjo est présenté avec plus d’une décennie d’expérience en gestion communautaire des ressources naturelles à Andasibe. Sont ainsi exposés les défis et les succès d'une organisation de conservation gérée par la communauté qui gagne la confiance à travers une approche posée sur cinq piliers]: (i) le transfert de gestion des ressources naturelles à la communauté locale, (ii) l’écotourisme à base communautaire, (iii) la formation de para-scientifiques, (iv) la restauration de la forêt tropicale humide en augmentant les moyens de subsistance des gens vivant sur la périphérie, et (v) l’éducation environnementale. Les actions entreprises ont abouti à la création et la protection efficace de deux réserves gérées par la communauté, accompagnées de programmes de surveillance écologique. Grâce à la responsabilisation des collectivités locales dans la protection de la biodiversité, elles montrent une fierté des actions entreprises qui est un indice prometteur pour la conservation des ressources naturelles et de la biodiversité à Madagascar et ailleurs

Long-Term Isoflurane Therapy for Refractory Bronchospasm Associated with Herpes Simplex Pneumonia in a Heart Transplant Patient

A 47-year-old man with a history of heart transplant was admitted after severe traumatic brain injury and seizures. During mechanical ventilation, the patient developed bronchospasm that severely compromised respiratory function that led to cardiac arrest. After resuscitation, application of isoflurane through the Anaesthetic Conserving Device (AnaConDa) in the ICU successfully treated bronchospasm, provided adequate sedation, and enabled appropriate ventilation and diagnostic bronchoscopy. A subsequent bronchoalveolar lavage revealed a high amount of Herpes simplex DNA. Herpes simplex pneumonia was diagnosed and treated with acyclovir. Isoflurane treatment was applied for twelve days total without side effects on renal and cerebral function. The patient recovered quickly after the termination of sedation. At discharge, he was fully awake without focal neurological deficiency and his long-term outcome was excellent. This case demonstrates that isoflurane is a treatment option in life-threatening cases of bronchospasm and a safe option for long-term sedation

Toponyms for centers of endemism in Madagascar

A biogeographical model was proposed in 2006 to explain the centers of endemism and the importance of riparian forest of some watersheds as refuges or dispersal corridors during paleoclimatic oscillations. Here, we consider these geographical features highlighting their biological and socio-cultural importance. We explain the etymology or eponymy of the major rivers of the retreat - dispersal watersheds, i.e., the drainage basins of Bemarivo, Antainambalana, Mangoro, Manampatrana, Mananara South, Mandrare, Onilahy, Mangoky, Tsiribihina, Betsiboka, Maevarano, Sambirano, and Mahavavy North. We propose a toponymy for each of the 15 centers of endemism and highlight their peculiarities. We named the centers of endemism of Vohimarina, Masoala, Analanjirofo, Tanala, Manombo, Anosy, Ranopiso, Karimbola, Mikea, Menabe, Melaky, Sofia, Ampasindava, Ankify, and Ankarana. We illustrate each center of endemism with a flagship species and report on its natural and cultural histories, and conservation.RÉSUMÉUn modèle biogéographique a été proposé en 2006 pour expliquer les centres d’endémisme de la biodiversité et l’importance des ripisylves de certains bassins versants en tant que refuges ou couloirs de dispersion au cours des oscillations paléoclimatiques. Ici, nous considérons ces dispositifs géographiques en soulignant leur importance biologique et socio-culturelle. Dans un premier temps, nous expliquons la toponymie ou l’éponymie des grands fleuves des bassins refuges et de dispersion, à savoir les bassins de la Bemarivo, de l’Antainambalana, du Mangoro, de la Manampatrana, de la Mananara du Sud, du Mandrare, de l’Onilahy, du Mangoky, de la Tsiribihina, de la Betsiboka, de la Maevarano, du Sambirano et de la Mahavavy du Nord. Puis nous proposons une toponymie pour chacun des 17 centres et sous-centres d’endémisme en justifiant leurs particularités. Nous retenons ainsi les centres d’endémisme de Vohimarina, de l’Atsinanana (dont Masoala et Analanjirofo), Tanala, de Manombo, de l’Anosy, d’Ala maika (dont Ranopiso, Karimbola et Mikea), du Menabe, du Melaky, de la Sofia, d’Ampasindava, d’Ankify et de l’Ankarana. Nous illustrons chacun des centres d’endémisme avec une espèce symbolique et rapportons des aspects de son histoire naturelle et culturelle ainsi que de sa conservation

Gram-negative and -positive bacteria differentiation in blood culture samples by headspace volatile compound analysis

BACKGROUND: Identification of microorganisms in positive blood cultures still relies on standard techniques such as Gram staining followed by culturing with definite microorganism identification. Alternatively, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry or the analysis of headspace volatile compound (VC) composition produced by cultures can help to differentiate between microorganisms under experimental conditions. This study assessed the efficacy of volatile compound based microorganism differentiation into Gram-negatives and -positives in unselected positive blood culture samples from patients. METHODS: Headspace gas samples of positive blood culture samples were transferred to sterilized, sealed, and evacuated 20 ml glass vials and stored at −30 °C until batch analysis. Headspace gas VC content analysis was carried out via an auto sampler connected to an ion–molecule reaction mass spectrometer (IMR-MS). Measurements covered a mass range from 16 to 135 u including CO(2), H(2), N(2), and O(2). Prediction rules for microorganism identification based on VC composition were derived using a training data set and evaluated using a validation data set within a random split validation procedure. RESULTS: One-hundred-fifty-two aerobic samples growing 27 Gram-negatives, 106 Gram-positives, and 19 fungi and 130 anaerobic samples growing 37 Gram-negatives, 91 Gram-positives, and two fungi were analysed. In anaerobic samples, ten discriminators were identified by the random forest method allowing for bacteria differentiation into Gram-negative and -positive (error rate: 16.7 % in validation data set). For aerobic samples the error rate was not better than random. CONCLUSIONS: In anaerobic blood culture samples of patients IMR-MS based headspace VC composition analysis facilitates bacteria differentiation into Gram-negative and -positive. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40709-016-0040-0) contains supplementary material, which is available to authorized users