512 research outputs found

    Revitalization of former industrial space versus sustainable development – the ‘Phoenix dortmund’ project (Ruhr area, Germany)

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    В сборнике материалов конференции отражены научно-методические и прикладные результаты научных исследований, анализа, оценки, регулирования, картографического и ГИС-обеспечения современных структурных и региональных сдвигов в мировом хозяйстве, социально-экономической модернизации стран и регионов СНГ в условиях глобализации, инновационных факторов социально-экономического развития регионов Беларуси, демографического развития и социально-демографических рисков стран, современных региональных проблем развития туризма, природно-ресурсного потенциала стран и регионов, геоэкологических аспектов стратегии устойчивого развития. Адресуется преподавателям, научным работникам, студентам и аспирантам вузов, сотрудникам органов управления

    PHP187 Pharmacovigilance and the Case Study of VIOXX

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    A Catalogue of Solar X-ray Plasma Ejections observed by the Soft X-ray Telescope onboard YOHKOH

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    A catalogue of X-ray Plasma Ejections (XPEs) observed by the Soft X-ray Telescope onboard the YOHKOH satellite has been recently developed in the Astronomical Institute of the University of Wroc{\l}aw. The catalogue contains records of 368 events observed in years 1991-2001 including movies and crossreferences to associated events like flares and Coronal Mass Ejections (CMEs). 163 XPEs from 368 in the catalogue were not reported until now. A new classification scheme of XPEs is proposed in which morphology, kinematics, and recurrence are considered. The relation between individual subclasses of XPEs and the associated events was investigated. The results confirm that XPEs are strongly inhomogeneous, responding to different processes that occur in the solar corona. A subclass of erupting loop-like XPEs is a promising candidate to be a high-temperature precursor of CMEs.Comment: 70 pages, 25 figures, 7 tables, accepted by The Astrophysical Journal Supplement Serie

    The application of whole-body vibration in physiotherapy – A narrative review

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    Whole-body vibration (WBV) training is a very popular kind of practice in sport, fitness and physiotherapy. This work reviews the current knowledge regarding the use and effectiveness of WBV in the physiotherapy. The discrepancies between different authors’ results are probably due to divergence in WBV training protocols. The paperwork clearly showed that despite its ultimate effects, exercises on a vibration platform are safe, feasible, and well tolerated by patients with different disorders. This narrative review should help physiotherapists verify therapy programs regarding patients’ exposure to WBV

    Embryonic and adult isoforms of XLAP2 form microdomains associated with chromatin and the nuclear envelope

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    Laminin-associated polypeptide 2 (LAP2) proteins are alternatively spliced products of a single gene; they belong to the LEM domain family and, in mammals, locate to the nuclear envelope (NE) and nuclear lamina. Isoforms lacking the transmembrane domain also locate to the nucleoplasm. We used new specific antibodies against the N-terminal domain of Xenopus LAP2 to perform immunoprecipitation, identification and localization studies during Xenopus development. By immunoprecipitation and mass spectrometry (LC/MS/MS), we identified the embryonic isoform XLAP2γ, which was downregulated during development similarly to XLAP2ω. Embryonic isoforms XLAP2ω and XLAP2γ were located in close association with chromatin up to the blastula stage. Later in development, both embryonic isoforms and the adult isoform XLAP2β were localized in a similar way at the NE. All isoforms colocalized with lamin B2/B3 during development, whereas XLAP2β was colocalized with lamin B2 and apparently with the F/G repeat nucleoporins throughout the cell cycle in adult tissues and culture cells. XLAP2β was localized in clusters on chromatin, both at the NE and inside the nucleus. Embryonic isoforms were also localized in clusters at the NE of oocytes. Our results suggest that XLAP2 isoforms participate in the maintenance and anchoring of chromatin domains to the NE and in the formation of lamin B microdomains

    Evolution of foreland basin fluvial systems in the mid-Cretaceous of Utah, USA (upper Cedar Mountain and Naturita formations)

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    ACKNOWLEDGEMENTS This work was funded by the SAFARI group. We are deeply grateful to Joe Phillips, Sean Kelly, James Mullins, Ryan King and Jostein Myking Kjærefjord for help in the field. We would also like to thank Associate Editor, Christopher Fielding, for handling the review of this paper. Additionally we thank reviewers Benjamin Cardenas and Brian Currie for their comments and suggested revisions which have greatly enhanced this paper. Open Access via the Jisc Wiley AgreementPeer reviewedPublisher PD
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