Discordance in the minimal inhibitory concentrations of ertapenem for Enterobacter cloacae: Vitek 2 system versus Etest and agar dilution methods

Our objective was to compare the ertapenem minimal inhibitory concentrations (MICs) for Enterobacter cloacae isolates categorized intermediate or resistant to ertapenem when measured with the Vitek 2 system, with the MICs for these isolates when measured by two methods performed in agar medium: the Etest and agar plate dilution method (APDM). Overall, 50 E. cloacae isolates were included in the study. The mean MIC of ertapenem was 2.92±1.77μg/ml according to the Vitek 2 system, 0.94±0.84μg/ml according to the Etest strips, and 0.93±0.62μg/ml according to the APDM. Furthermore, the MICs determined by the Vitek 2 system were higher than the MICs determined by the two other methods for 96% of strains. Lastly, according to the Etest strips and APDM, 42% of E. cloacae were susceptible to ertapenem. No carbapenemase was identified by the screening method used. Using the Vitek 2 system to determine ertapenem MICs for E. cloacae can have potential consequences in terms of additional carbapenemase-detecting tests and antimicrobial therapy. It would be interesting to determine if the Vitek 2 system is more effective for the detection of carbapenemase producers with low-level carbapenem resistance than the two methods performed in agar medium

A qualitative study into the perceived barriers of accessing healthcare among a vulnerable population involved with a community centre in Romania

(1) Interview guide for family members, and (2) Interview guide for staff members. (DOCX 103 kb

Some Integral Geometry Tools to Estimate the Complexity of 3D Scenes

: Many problems in computer graphics deal with complex 3D scenes where visibility, proximity, collision detection queries have to be answered. Due to the complexity of these queries and the one of the models they are applied to, data structures most often based on hierarchical decompositions have been proposed to solve them. As a result of these involved algorithms/data structures, most of the analysis have been carried out in the worst case and fail to report good average case performances in a vast majority of cases. The goal of this work is therefore to investigate geometric probability tools to characterize average case properties of standard scenes such as architectural scenes, natural models, etc under some standard visibility and proximity requests. In the first part we recall some fundamentals of integral geometry and discuss the classical assumption of measures invariant under the group of motions in the context of non uniform models. In the second one we present simple genera..

InstantDB: Enforcing Timely Degradation of Sensitive Data

Abstract- People cannot prevent personal information from being collected by various actors. Several security measures are implemented on servers to minimize the possibility of a privacy violation. Unfortunately, even the most well defended servers are subject to attacks and however much one trusts a hosting organism/company, such trust does not last forever. We propose a simple and practical degradation model where sensitive data undergoes a progressive and irreversible degradation from an accurate state at collection time, to intermediate but still informative fuzzy states, to complete disappearance. We introduce the data degradation model and identify related technical challenges and open issues. I